Enhanced Absorption of Phenobarbital from Suppositories Containing Amino Acid and Choline Salts of Phenobarbital(Pharmaceutical,Chemical)
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概要
- 論文の詳細を見る
Dissolution ana permeation patterns of phenobarbital (PB) from basic amino acid and choline salts of PB indicated that drug dissolution from the salts was faster than that of PB itself. Release of the drug from Vosco H15 suppositories containing the salts was faster than that from the suppository containing PB itself. After rectal administration of suppositories containing the salts to rabbits, the blood levels were significantly (p <0.05) higher than those following administration of the suppository containing PB itself during a period from 30min to 2h.
- 公益社団法人日本薬学会の論文
- 1987-11-25
著者
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中野 眞汎
Department Of Pharmacy Kumamoto University Hospital
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岩奥 玲子
熊本大学医学部附属病院薬剤部
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岩奥 玲子
Department of Pharmaceutical Services, Kumamoto University Hospital
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中野 眞汎
Department of Clinical Pharmaceutics, Graduate School of Pharmaceutical Sciences, University of Shizuoka
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