Synthesis of Disulfates of Unconjugated and Conjugated Bile Acids(Analytical,Chemical)
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概要
- 論文の詳細を見る
The disulfates of unconjugated, and glycine- and taurine-conjugated bile acids have been synthesized. Cholic acid derivatives appropriately protected were sulfated with sulfur trioxide-triethylamine complex in pyridine in the, usual manner. Subsequent hydrolysis and/or sodium borohydride reduction provided the desired disulfates of cholates in satisfactory, yields. Dihydroxy-lated bile acid disulfates were also prepared. The nuclear magnetic resonance spectral data for bile acid disulfates and related compounds are tabulated.
- 公益社団法人日本薬学会の論文
- 1987-11-25
著者
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後藤 順一
Pharmaceutical Institute Tohoku University
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南原 利夫
東北大学医学部薬学科
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南原 利夫
Pharmaceutical Institute Tohoku University
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佐野 善寿
Pharmaceutical Institute Tohoku University
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千海 俊幸
東北大学薬学部
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千海 俊幸
Pharmaceutical Institute, Tohoku University
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