Enzyme Histochemical and Ultrastructural Approach in Orotic Acid-induced Fatty Liver and Their Recovery Process in Wistar Rats
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概要
- 論文の詳細を見る
Fatty liver was induced in Wistar rats by orotic acid and the recovery process was studied by enzyme histochemical staining for non specific esterase, lipase and by ultrastructural investigation. Enzyme histochemically, these enzyme activities were markedly decreased in orotic acid-induced fatty liver. However, during the recovery process after the end of orotic acid administration, these enzyme activities clearly appeared. Under these conditions, no significant ultrastructural alterations could be detected. Based on our data, pathogenesis of orotic acid-induced fatty liver was discussed.
- 東海大学の論文
著者
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Watanabe Keiichi
Department Of Internal Medicine School Of Medicine Tokai University
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Murakoshi M
(present Address)products Strategy Dcpartment Pharma Business Strategy Division Teikoku Hormone Mfg.
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Murakoshi Masanori
Safety Res. Dept. Teikoku Hormone Mfg Co. Ltd.
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Suemizu Hiroshi
Department Of Pathology Tokai University School Of Medicine
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Watanabe Keiichi
Department Of Applied Biological Science Faculty Of Agriculture Saga University
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