CHARACTERISTIC IMMUNOCYTOCHEMICAL LOCALIZATION OF GLUTATHIONE-PEROXIDASE (GSH-PO) IN RAT TESTICULAR INTERSTITIAL MACROPHAGES
スポンサーリンク
概要
- 論文の詳細を見る
An immunohisto-cytochemical localization of glutathione-peroxidase (GSH-PO) in rat testicular interstitial macrophages was studied on 1) normal untreated rats 2) 2 weeks after hypophysectomy 3) and with gonadotropin administration for 1 week after hypophysectomy, in order to clarify the role of GSH-PO. In group 1, an immunohisto-cytochemical localization of GSH-PO was observed in cytosol as a characteristic lysosome-like structure. In group 2, immunohistochemically, the number of GSH-PO positive macrophages decreased as compared with that of the group 1. However, in group 3, immunohistochemically, the number of GSH-PO positive macrophages increased as compared with that of group 2. An intracellular lysosome-like GSH-PO also increased as compared with that of the other groups. These findings suggest that a very close relationship lies between immuno-cytochemical localization of GSH-PO in the testicular interstitial macrophages and testosterone production in the testicular Leydig cells. The possible role of GSH-PO in the testicular interstitial macrophage is discussed.
- 日本組織細胞化学会の論文
著者
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Osamura Yoshiyuki
Department of Pathology Tokai University School of Medicine
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YOSHIMURA Shinichi
Department of Neurosurgery, Graduate School of Medicine, Gifu University
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Osamura R
Department Of Pathology School Of Medicine Tokai University
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Watanabe Keiichi
Department Of Internal Medicine School Of Medicine Tokai University
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MURAKOSHI Masanori
Departments of Pathology, School of Medicine, Tokai University
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Osamura Yoshiyuki
Department Of Pathology Tokai University School Of Of Medicine
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Yoshimura Shinichi
Departments Of Cell Biology Tokai University School Of Medicine
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Yoshimura S
Department Of Molecular Life Science (cell Biology Division) Tokai University School Of Medicine
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Murakoshi M
(present Address)products Strategy Dcpartment Pharma Business Strategy Division Teikoku Hormone Mfg.
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Murakoshi Masanori
Department Of Pathology School Of Medicine Tokai University
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Osamura Yoshiyuki
Department Of Surgery Tokai University School Of Medicine
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Yoshimura Shinichi
Department Of Molecular Life Science Tokai University School Of Medicine
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Osamura Yoshiyuki
Department Of Pathodiagnostics Course Of Basic Clinical Science Tokai University School Of Medicine
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Osamura Yoshiyuki
Department Of Internal Medicine Tokai University School Of Medicine
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Yoshimura Shinichi
Department Of Molecular Life Science (cell Biology) Tokai University School Of Medicine
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Watanabe Keiichi
Department Of Applied Biological Science Faculty Of Agriculture Saga University
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Yoshimura Shinichi
Department of Molecular Life science (Cell Biology Division), Tokai University School of Medicine
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