Enzyme Histo-cytochemical Studies in Human Adrenocortical Adenomas [II] Cushing's Syndrome
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概要
- 論文の詳細を見る
Enzyme histo-cytochemical staining was performed for 3β-hydroxysteroid dehydrogenase, alkaline phosphatase and acid phosphatase in the compact and clear cells of the adrenocortical adenomas associated with Cushing's syndrome (Cushing's adenomas). In the compact cells, enzymatic activities of 3β-hydroxysteroid dehydrogenase and alkaline phosphatase were stronger than those in the clear cells. Electron microscopic localization of alkaline phosphatase was mostly present on well developed microvilli, while, acid phosphatase was observed in lysosomes near the well developed smooth endoplasmic reticula. On the other hand, in the clear cells, cytochemical localization of alkaline phosphatase was mainly present on the intercellular plasma membrane, while acid phosphatase was mostly observed near the lipid droplets. Based on these data, functional aspects of the compact and clear cells in Cushing's adenomas are discussed.
- 東海大学の論文
著者
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Osamura Yoshiyuki
Department of Pathology Tokai University School of Medicine
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NOMOTO Yasuo
Department of Internal Medicine, School of Medicine, Tokai University
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SAKAI Hideto
Department of Internal Medicine, School of Medicine, Tokai University
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Sakai H
Division Of Nephrology And Metabolism Department Of Internal Medicine
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Watanabe Keiichi
Department Of Internal Medicine School Of Medicine Tokai University
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Nomoto Yasuo
Department Of Intermal Medicine School Of Medicine Tokai University
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Sakai Hideto
Department Of Intermal Medicine School Of Medicine Tokai University
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Nomoto Yasuo
Division Of Nephrology And Metabolism Department Of Internal Medicine Tokai University School Of Med
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Nomoto Yasuo
Division Of Nephrology Department Of Internal Medicine School Of Medicine Tokai University
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MURAKOSHI Masanori
Departments of Pathology, School of Medicine, Tokai University
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Murakoshi M
(present Address)products Strategy Dcpartment Pharma Business Strategy Division Teikoku Hormone Mfg.
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Murakoshi Masanori
Department Of Pathology School Of Medicine Tokai University
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Sakai Hideto
Division Of Nephrology And Metabolism Department Of Internal Medicine School Of Medicine Tokai Unive
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Osamura Yoshiyuki
Department Of Internal Medicine Tokai University School Of Medicine
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Watanabe Keiichi
Department Of Applied Biological Science Faculty Of Agriculture Saga University
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Sakai Hideto
Department Of Health Care Policy And Management Graduate School Of Comprehensive Sciences University Of Tsukuba
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