Enzyme Histocytochemical Studies in Human Adrenocortical Adenomas : [I] Primary aldosteronism
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概要
- 論文の詳細を見る
Enzyme histocytochemical staining including alkaline phosphatase, acid phosphatase, 3βhydroxysteroid dehydrogenase and 11βhydroxysteroid dehydrogenase was studied in human adrenocortical adenomas associated with primary aldosteronism. Histochemically, these enzyme activities were weaker in clear cell type adenomas than in the normal human adrenal cortex. While compact cell type adenomas showed stronger enzyme activities than the clear cell type adenomas. Electron microscopic localization of alkaline phosphatase was mainly observed in plasma membrane at the intercellular sites. Occasionally, this enzyme activity was also observed in the mitochondrial outer membrane, mainly in compact cells. The significance of these enzymes in the adenoma cells is discussed.
- 東海大学の論文
著者
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Osamura Yoshiyuki
Department of Pathology Tokai University School of Medicine
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NOMOTO Yasuo
Department of Internal Medicine, School of Medicine, Tokai University
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SAKAI Hideto
Department of Internal Medicine, School of Medicine, Tokai University
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Sakai H
Division Of Nephrology And Metabolism Department Of Internal Medicine
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Watanabe Keiichi
Department Of Internal Medicine School Of Medicine Tokai University
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Nomoto Yasuo
Department Of Intermal Medicine School Of Medicine Tokai University
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Sakai Hideto
Department Of Intermal Medicine School Of Medicine Tokai University
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KAWAKAMI TAKESHI
Department of Internal Medicine, Tone Chuo Hospital
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Nomoto Yasuo
Division Of Nephrology And Metabolism Department Of Internal Medicine Tokai University School Of Med
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Nomoto Yasuo
Division Of Nephrology Department Of Internal Medicine School Of Medicine Tokai University
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MURAKOSHI Masanori
Departments of Pathology, School of Medicine, Tokai University
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IZUMI Shinichi
Divisions of Cell Biology Research laboratory, School of Medicine, Tokai University
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Kawakami Takeshi
Department Of Diagnostic Pathology School Of Medicine Tokai University
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Murakoshi M
(present Address)products Strategy Dcpartment Pharma Business Strategy Division Teikoku Hormone Mfg.
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Izumi Shinichi
Dept. Of Cell Biology Research Laboratory Tokai Univ.
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Murakoshi Masanori
Department Of Pathology School Of Medicine Tokai University
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Osamura Yoshiyuki
Department Of Pathodiagnostics Course Of Basic Clinical Science Tokai University School Of Medicine
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Sakai Hideto
Division Of Nephrology And Metabolism Department Of Internal Medicine School Of Medicine Tokai Unive
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Osamura Yoshiyuki
Department Of Internal Medicine Tokai University School Of Medicine
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Watanabe Keiichi
Department Of Applied Biological Science Faculty Of Agriculture Saga University
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Sakai Hideto
Department Of Health Care Policy And Management Graduate School Of Comprehensive Sciences University Of Tsukuba
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