Inhibitory Effects of Shouseiryu-to on Two-Stage Carcinogenesis. II.Anti-tumor-promoting Activities of Lignans from Asiasarum heterotropoides var. mandshuricum
スポンサーリンク
概要
- 論文の詳細を見る
Two lignans, asarinin (6) and xanthoxylol (7), were isolated from the radix of Asiasarum heterotropoides var. mandshuricum, which consist of a kampo prescription, Shouseiryu-to, as inhibitors of Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA). These lignans also exhibited remarkable inhibitory effects on a two-stage carcinogenesis test of mouse skin and pulmonary tumors. Furthermore, it was confirmed that these hydrophobic lignans dissolved in the water decoction of Shouseiryu-to, and these lignans might be among the active consituents of this kampo prescription in terms of its anti-tumor-promoting activity.
- 公益社団法人日本薬学会の論文
- 1997-07-15
著者
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Kim Tae-hoon
Faculty Of Pharmaceutical Sciences Okayama University
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Yasuda Ichiro
First Department Of Internal Medicine Gifu University Hospital
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Yasuda I
Gifu Univ. School Of Medicine Gifu Jpn
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KONOSHIMA Takao
Kyoto Pharmaceutical University
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TOKUDA Harukuni
Kyoto Prefectural University of Medicine
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TAKASAKI Midori
Kyoto Pharmaceutical University
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Machiguchi Takahisa
Faculty Of Science Saitama University
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Yasuda Ichiro
岐阜大学 医学系研究科第一内科
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Tokuda Harukuni
Dep. Of Complementary And Alternative Medicine Clinical R&d Graduate School Of Medical Sci. Kana
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Tokuda H
Department Of Biochemistry Kyoto Prefectural University Of Medicine
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Tokuda Harukuni
Department Of Microbiology Faculty Of Medicine Kyoto University
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Tokuda Harukuni
Department Of Biochemistry Kyoto Prefectural University Of Medicine
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Tokuda Harukuni
Dept. Of Biochemistry Kyoto Prefectural University Of Medicine
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Konoshima T
Kyoto Pharmaceutical University
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Konoshima Takao
Faculty Of Pharmacy Chiba Institute Of Science
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Yasuda I
First Department Of Internal Medicine Gifu University School Of Medicine
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YASUDA Ichiro
Tokyo Metropolitan Research Laboratory of Public Health
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HAMANO Tomoko
Tokyo Metropolitan Research Laboratory of Public Health
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米谷 民雄
Division Of Foods National Institute Of Health Sciences
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Konoshima T
Pharmaceutical Sciences Okayama University Graduate School Of Medicine Dentistry And Pharmaceutical
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Konoshima T
Pharmaceutical Sciences Okayama University Graduate School Of Medicine Dentistry And Pharmaceutical
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Konoshima Takao
Pharmaceutical Sciences Okayama University Graduate School Of Medicine Dentistry And Pharmaceutical
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HAMANO Tomoko
Tokyo Metropolitan Industrial Technology Research Institute
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