Anti-carcinogenic Activity of Taraxacum Plant. I

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概要

• 論文の詳細を見る

• An extract of the roots of Taraxacum japonicum (Compositae) exhibited strong anti-tumor-promoting activities on the two-stage carcinogenesis of mouse skin tumor induced by dimethylbenz[a]anthracene (DMBA) as an initiator and 12-O-tetradecanoylphorbol-13-acetate (TPA) as a promoter, as well as on that induced by DMBA and fumonisin B1. Further, the extract exhibited anti-tumor-initiating activity on the two-stage carcinogenesis of mouse skin tumor induced by (±)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexenamide (NOR-1) as an initiator and TPA as a promoter. These results suggested that an extract of the roots of the Taraxacum plant could be a valuable chemopreventive agent against chemical carcinogenesis.

• 公益社団法人日本薬学会の論文
• 1999-06-15

著者

• 上田 博之

  昭和薬大

• Kim Tae-hoon

  Faculty Of Pharmaceutical Sciences Okayama University

• MASUDA Kazuo

  Showa Pharmaceutical University

• Arai Y

  Showa Pharmaceutical University

• 荒井 洋子

  富士レビオ(株)医薬研究所

• Arai Yoko

  Showa College Of Pharmaceutical Sciences

• Masuda K

  Showa Pharmaceutical Univ.

• Masuda Kazuo

  Showa College Of Pharmaceutical Sciences

• SHIOJIMA Kenji

  Showa Pharmaceutical University

• AGETA Hiroyuki

  Showa Pharmaceutical University

• Masuda K

  Showa Pharmaceutical University

• KONOSHIMA Takao

  Kyoto Pharmaceutical University

• TOKUDA Harukuni

  Kyoto Prefectural University of Medicine

• TAKASAKI Midori

  Kyoto Pharmaceutical University

• Takagi Miyuki

  Faculty Of Pharmacy Chiba Institute Of Science

• Machiguchi Takahisa

  Faculty Of Science Saitama University

• Tokuda Harukuni

  Dep. Of Complementary And Alternative Medicine Clinical R&d Graduate School Of Medical Sci. Kana

• Konoshima T

  Kyoto Pharmaceutical University

• Konoshima Takao

  Faculty Of Pharmacy Chiba Institute Of Science

• 塩島 憲治

  Showa Pharmaceutical University

• Masuda K

  Shionogi Research Laboratories Shionogi & Co. Ltd.

• Shiojima Kenji

  Ntt Photonics Laboratories

• Shiojima Kenji

  Showa College Of Pharmaceutical Sciences

• Ageta Hiroyuki

  Showa College Of Pharmaceutical Sciences

• 上田 博之

  Showa Coll. Pharmaceutical Sci. Tokyo Jpn

• 米谷 民雄

  Division Of Foods National Institute Of Health Sciences

• Konoshima T

  Pharmaceutical Sciences Okayama University Graduate School Of Medicine Dentistry And Pharmaceutical

• Konoshima T

  Pharmaceutical Sciences Okayama University Graduate School Of Medicine Dentistry And Pharmaceutical

• Konoshima Takao

  Pharmaceutical Sciences Okayama University Graduate School Of Medicine Dentistry And Pharmaceutical

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