β_3-Adrenoceptor Is Involved in the Inhibition of Small Intestinal Motility Due to Restraint Stress in Rats

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概要

• 論文の詳細を見る

• We have reported that acute restraint stress inhibits small intestinal motility in rats. In order to clarify this inhibitory mechanism, we examined the effects of α- and β-adrenergic antagonists on the inhibition of small intestinal motility induced by restraint stress. This inhibition underwent recovery by propranolol(β_1/β_2-antagonist)or SR59230A(β_3-antagonist), but not by atenolol(β_1-antagonist), ICI-118, 551(β_2-antagonist), prazosin(α_1-antagonist)or yohimbine(α_2-antagonist). These results suggest that β_3-adrenoceptors play an important role in the inhibition of small intestinal motility caused by restraint stress.(

• 公益社団法人日本薬学会の論文
• 2001-09-01

著者

• KOHNO Hiroyuki

  Department of Oncologic Pathology, Kanazawa Medical University

• Kohno Hiroyuki

  東北薬科大学 放射薬品

• OHKUBO Yasuhito

  Department of Radiopharmacology, Tohoku Pharmaceutical University

• Kohno H

  Department Of Radiopharmacy Tohoku Pharmaceutical University

• SAWAMURA Kuniko

  Department of Radiopharmacy, Tohoku Pharmaceutical University

• OHUCHI Yukie

  Department of Radiopharmacy, Tohoku Pharmaceutical University

• TSUKADA Fumitaka

  Department of Radiopharmacy, Tohoku Pharmaceutical University

• SUGAWARA Mika

  Department of Radiopharmacy, Tohoku Pharmaceutical University

• Ohuchi Yukie

  Department Of Radiopharmacy Tohoku Pharmaceutical University

• Sugarawa Mika

  Department Of Radiopharmacy Tohoku Pharmaceutical University

• Sawamura Kuniko

  Department Of Radiopharmacy Tohoku Pharmaceutical University

• Ohkubo Yasuhito

  Department Of Radiopharmacology Tohoku Pharmaceutical University

• Tsukada Fumitake

  Department Of Radiopharmacy Tohoku Pharmaceutical University

• Tsukada Fumitake

  Department Of Radiophunnacy Tohoku Pharmaceutical University

• Kohno Hiroyuki

  Department Of Chemistry Faculty Of Science Science University Of Tokyo

• 大窪 芳子

  Department Of Radiopharmacy Tohoku Pharmaceutical University

• 大窪 芳子

  熊本大学 薬

• KOHNO Hiroyuki

  Department of Chemical Pharmacology, Tohoku College of Pharmacy

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