Involvement of Transglutaminase in the Receptor-Mediated Endocytosis of Mouse Peritoneal Macrophages
スポンサーリンク
概要
- 論文の詳細を見る
We investigated the effect of extracellular Ca^<2+> on the uptake of immunoglobulin G (IgG)-coated normal sheep red blood cells (SRBC) by the mouse peritoneal macrophages. The uptake of SRBC was dose dependently enhanced by Ca^<2+> concentration. We also investigated the effect of ryanodine on the uptake of SRBC. Ryanodine showed approximately 15% inhibition of the uptake. The activity of transglutaminase (TGase) in the cytosolic fraction of macrophages was enhanced as the Ca^<2+> concentration increased. The uptake of SRBC decreased by the addition of histamine, a TGase inhibitor. These results suggest that TGase is involved in the receptor-mediated endocytosis system of mouse peritoneal macrophages.
- 公益社団法人日本薬学会の論文
- 2000-12-01
著者
-
KOHNO Hiroyuki
Department of Oncologic Pathology, Kanazawa Medical University
-
Kohno Hiroyuki
Department Of Radiopharmacy Tohoku Pharmaceutical University
-
OHKUBO Yasuhito
Department of Radiopharmacology, Tohoku Pharmaceutical University
-
ABE Shinya
Department of Radiopharmacy, Tohoku Pharmaceutical University
-
Ohkubo Yasuhito
Department Of Radiopharmacology Tohoku Pharmaceutical University
-
Abe Shinya
Department Of Radiopharmacy Tohoku Pharmaceutical University
-
Kohno Hiroyuki
Department Of Chemistry Faculty Of Science Science University Of Tokyo
-
Yamashita Kei
Department Of Radiopharmacy Tohoku Pharmaceutical University
-
Abe Shinya
Department Of Cardiology Tobu Chiiki Hospital Tokyo Metropolitan Health And Medical Treatment Corpor
-
KOHNO Hiroyuki
Department of Chemical Pharmacology, Tohoku College of Pharmacy
関連論文
- Lack of Enhancing Effect of Lauric Acid on the Development of Aberrant Crypt Foci in Male ICR Mice Treated with Azoxymethane and Dextran Sodium Sulfate
- The Modified High-Density Survival Assay is the Useful Tool to Predict the Effectiveness of Fractionated Radiation Exposure
- A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate
- Inhibitory effects of troglitazone, a peroxisome proliferator-activated receptor γ ligand, in rat tongue carcinogenesis initiated with 4-nitroquinoline 1-oxide
- Mechanistic Insights of Carcinogenesis and Anti-carcinogenesis by Dietary Compounds
- Preventive Effects of Powdered Broccoli Sprout on Azoxymethane-induced Rat Colonic Aberrant Crypt Foci
- The Modified High-Density Survival Assay is the Useful Tool to Predict the Effectiveness of Fractionated Radiation Exposure
- Effect of Phospholipids Containing Docosahexaenoic Acid on Differentiation and Growth of HL-60 Human Promyelocytic Leukemia Cells
- Sequential observations on the occurrence of preneoplastic and neoplastic lesions in mouse colon treated with azoxymethane and dextran sodium sulfate
- Lack of modifying effects of 4-tert-octylphenol and benzyl butyl phthalate on 3, 2'-dimethyl-4-aminobiphenyl-induced prostate carcinogenesis in rats
- Synergistic Effects of Highly Unsaturated Fatty Acid-containing Phosphatidyl-ethanolamine of Differentiation of Human Leukemia HL-60 Cells by Dibutyryl Cyclic Adenosine Monophosphate
- Apoptosis-Inducing Effect of Fucoxanthin on Human Leukemia Cell Line HL-60
- Chemopreventive Effect of Bovine Lactoferrin on 4-Nitroquinoline 1-Oxide-induced Tongue Carcinogenesis in Male F344 Rats
- Relationship between Liver Injury and Transglutaminase Activities in Guinea Pigs and Rats(Pharmacology)
- Pomegranate seed oil rich in conjugated linolenic acid suppresses chemically induced colon carcinogenesis in rats
- Dietary Conjugated Linolenic Acid Inhibits Azoxymethane-induced Colonic Aberrant Crypt Foci in Rats
- Potent inhibitory effect of trans9, trans11 isomer of conjugated linoleic acid on the growth of human colon cancer cells
- Troglitazone, a Ligand for Peroxisome Proliferator-activated Receptor γ, Inhibits Chemically-induced Aberrant Crypt Foci in Rats
- Indications and Operative Techniques for Combined Aortoesophageal Resection
- Design, Synthesis And Characterization of DNA Binding Peptides
- The Effect of Blood Decrease on ^Ga Uptake by the Liver in Partially Hepatectomized Rats(Biopharmacy)
- Prevention of Colonic Preneoplastic Lesions by the β-Cryptoxanthin and Hesperidin Rich Powder Prepared from Citrus Unshiu Marc. Juice in Male F344 Rats
- Changes in Ingestive Behavior Induced by Intracranial Injection of Spermine
- Clock Skew Evaluation Considering Manufacturing Variability in Mesh-Style Clock Distribution
- Mechanism of Inhibition of Small Intestinal Motility by Restraint Stress Differs from That with Norepinephrine Treatment in Rats
- Activation of μ-Opioid Pathway Is Associated with the Canceling Effect of Footshock Stimulus on the Restraint Stress-Induced Inhibition of Small Intestinal Motility in Rats
- β_3-Adrenoceptor Is Involved in the Inhibition of Small Intestinal Motility Due to Restraint Stress in Rats
- Evaluation of the Effects of Restraint and Footshock Stress on Small Intestinal Motility by an Improved Method Using a Radionuclide, ^51Cr, in the Rat
- Possible Neural Mechanisms Involved in Footshock Stress-Induced Enhancement of Exploratory Behavior in Mice
- Clinically relevant radioresistant cells efficiently repair DNA double-strand breaks induced by X-rays
- Gene Expression Profiles in Mouse Liver Cells after Exposure to Different Types of Radiation
- Chemopreventive Effects of Nobiletin against Genotoxicity Induced by 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in the Lung of gpt delta Transgenic Mice
- Transferrin Is Not Involved in the Entry of^Ga into Hepatocytes from Regenerating Liver of Partially Hepatectomized Rats
- The Uptake Mechanism of Gallium-67 into Hepatocytes Treated with Carbon Tetrachloride(Biochemistry)
- The Involvement of Transferrin in the Uptake of Iron-59 by Hepatocytes of Carbon Tetrachloride-Damaged Rats(Pharmacology)
- The Involvement of Polyamines as Substrates of Transglutaminase in Zonal Different Hepatocyte Proliferation after Partial Hepatectomy(Biochemistry/Molecular Biology)
- Uptake of Gallium-67 by the Hepatocytes during Liver Regeneration in Carbon Tetrachloride-Treated Mice(Biochemistry/Molecular Biology)
- Zonal Differences in DNA Synthesis and in Transglutaminase Activity between Perivenous versus Periportal Regions of Regenerating Rat Liver(Biochemistry/Molecular Biology)
- Oxidative Stress Induced Lipocalin 2 Gene Expression : Addressing its Expression under the Harmful Conditions
- Involvement of Transglutaminase in the Receptor-Mediated Endocytosis of Mouse Peritoneal Macrophages
- Case of multiple cutaneous granular cell tumors
- DNA damage-induced apoptosis and genetic background of the host: Hostspecific signaling enhancers of apoptosis
- Differentiation-and Apoptosis-inducing Activities of Phospholipids Containing Docosahexaenoic Acid for Mouse Myeloid Leukemia M1 Cells
- Current Techniques of Hyperthermic Isolated Limb Perfusion for Malignant Melanoma
- Thermal and Optical Properties of Regioregular Polythiophene Derivatives Containing Mesogenic Group in the Side Chain
- Spermine Modulates Calcium Flux through the Rat Erythrocyte Membrane
- Comparative Glucoregulatory Responses of Mice to Restraint and Footshock Stress Stimuli
- Small Solid Pseudopapillary Tumor of the Pancreas in a 32-Year-Old Man : Report of a Case
- Free ^Ga enters into the hepatocytes of carbon tetrachloride-treated rats
- Development of an Experimental System for Evaluation of Stress Effect on Ethyl Alcohol Metabolism Using Radiorespirometric Analysis in Rat (Pharmacology)
- Zonal differences in gallium-67 uptakes between perivenous versus periportal regions of rat liver following carbon tetrachloride treatment
- PJ-499 Lateral E/Ea is the Most Reliable Predictor of Left Ventricular Filling Pressure in Patients with Old Myocardial Infarction(Echo/Doppler(16)(I),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- EFFECTS OF INTRACEREBROVENTRICULAR ADMINISTRATI OF ALIPHATIC DIAMINES ON INGESTIVE BEHAVIOR IN THE RAT
- Detection of liver metastases secondary to pancreatic cancer: Utility of combined helical computed tomography during arterial portography with biphasic computed tomography-assisted hepatic arteriography
- Antimicrobial-susceptible patterns of Staphylococcus aureus isolated from surgical infections : a new approach
- PHARMACOLOGICAL ACTIONS OF INTRACEREBRALLY ADMINISTERED POLYAMINES IN MICE
- The Entering of Indium-111 and Iron-59 into the Hepatocytes from Partially Hepatectomized Rats Differ from That of Gallium-67(Biochemistry/Molecular Biology)
- Effect of Restraint and Footshock Stress and Norepinephrine Treatment on Gastric Emptying in Rats
- Adenocarcinoma of the Minor Duodenal Papilla : Report of a Case
- Statistical Timing Analysis Considering Clock Jitter and Skew due to Power Supply Noise and Process Variation
- Estimation of mandibular growth using biological markers of bone metabolism in urine
- CHANGES IN INGESTIVE BEHAVIOR, SERUM GLUCOSE AND FREE FATTY ACIDS CONCENTRATIONS IN RATS FOLLOWING INTRACEREBROVENTRICULAR INJECTION OF SPERMINE
- A Possible Mechanism for the Exchange of Transferrin- ^Ga Complex to Heparan Sulfate- ^Ga Complex
- Development of an Experimental System for Evaluation of the Effect of Stress on Intestinal Motility Using a Radionuclide, ^Cr, in the Rat
- Experimental and Thermodynamic Studies of the Fe–Si Binary System
- Experimental and Thermodynamic Studies of the Fe-Si Binary System