A Possible Mechanism for the Exchange of Transferrin- ^<67>Ga Complex to Heparan Sulfate- ^<67>Ga Complex
スポンサーリンク
概要
- 論文の詳細を見る
We attempted to identify the exchange mechanism of transferrin- ^<67>Ga complex to heparan sulfate- ^<67>Ga complex. The effect of phosphate on the binding ability of ^<67>Ga to transferrin and heparan sulfate was studied by the dialysis method. The phosphate inhibited the binding ability of ^<67>Ga to transferrin, while the phosphate enhanced the ^<67>Ga binding ability to heparan sulfate. The results suggest that the phosphate is involved in the translocation of ^<67>Ga from the transferrin to the heparan sulfate.
- 公益社団法人日本薬学会の論文
- 2002-09-01
著者
-
Ohkubo Yasuhito
Department Of Radiopharmacology Tohoku Pharmaceutical University
-
Ohkubo Yasuhito
Department Of Radiopharmacy Tohoku Pharmaceutical University
-
Abe Shinya
Department Of Radiopharmacy Tohoku Pharmaceutical University
-
Abe Shinya
Department Of Cardiology Tobu Chiiki Hospital Tokyo Metropolitan Health And Medical Treatment Corpor
-
SHIMIZU Yositaka
Department of Radiopharmacy, Tohoku Pharmaceutical University
-
OHTSUKI Junko
Department of Radiopharmacy, Tohoku Pharmaceutical University
-
Ohtsuki Junko
Department Of Radiopharmacy Tohoku Pharmaceutical University
-
Shimizu Yoshitaka
Department of Radiopharmacy, Tohoku Pharmaceutical University
関連論文
- The Modified High-Density Survival Assay is the Useful Tool to Predict the Effectiveness of Fractionated Radiation Exposure
- Relationship between Liver Injury and Transglutaminase Activities in Guinea Pigs and Rats(Pharmacology)
- Design, Synthesis And Characterization of DNA Binding Peptides
- The Effect of Blood Decrease on ^Ga Uptake by the Liver in Partially Hepatectomized Rats(Biopharmacy)
- Clock Skew Evaluation Considering Manufacturing Variability in Mesh-Style Clock Distribution
- Mechanism of Inhibition of Small Intestinal Motility by Restraint Stress Differs from That with Norepinephrine Treatment in Rats
- Activation of μ-Opioid Pathway Is Associated with the Canceling Effect of Footshock Stimulus on the Restraint Stress-Induced Inhibition of Small Intestinal Motility in Rats
- β_3-Adrenoceptor Is Involved in the Inhibition of Small Intestinal Motility Due to Restraint Stress in Rats
- Evaluation of the Effects of Restraint and Footshock Stress on Small Intestinal Motility by an Improved Method Using a Radionuclide, ^51Cr, in the Rat
- Possible Neural Mechanisms Involved in Footshock Stress-Induced Enhancement of Exploratory Behavior in Mice
- Clinically relevant radioresistant cells efficiently repair DNA double-strand breaks induced by X-rays
- Gene Expression Profiles in Mouse Liver Cells after Exposure to Different Types of Radiation
- Transferrin Is Not Involved in the Entry of^Ga into Hepatocytes from Regenerating Liver of Partially Hepatectomized Rats
- The Uptake Mechanism of Gallium-67 into Hepatocytes Treated with Carbon Tetrachloride(Biochemistry)
- The Involvement of Transferrin in the Uptake of Iron-59 by Hepatocytes of Carbon Tetrachloride-Damaged Rats(Pharmacology)
- The Involvement of Polyamines as Substrates of Transglutaminase in Zonal Different Hepatocyte Proliferation after Partial Hepatectomy(Biochemistry/Molecular Biology)
- Uptake of Gallium-67 by the Hepatocytes during Liver Regeneration in Carbon Tetrachloride-Treated Mice(Biochemistry/Molecular Biology)
- Zonal Differences in DNA Synthesis and in Transglutaminase Activity between Perivenous versus Periportal Regions of Regenerating Rat Liver(Biochemistry/Molecular Biology)
- Oxidative Stress Induced Lipocalin 2 Gene Expression : Addressing its Expression under the Harmful Conditions
- Involvement of Transglutaminase in the Receptor-Mediated Endocytosis of Mouse Peritoneal Macrophages
- Case of multiple cutaneous granular cell tumors
- DNA damage-induced apoptosis and genetic background of the host: Hostspecific signaling enhancers of apoptosis
- Spermine Modulates Calcium Flux through the Rat Erythrocyte Membrane
- Comparative Glucoregulatory Responses of Mice to Restraint and Footshock Stress Stimuli
- Small Solid Pseudopapillary Tumor of the Pancreas in a 32-Year-Old Man : Report of a Case
- Free ^Ga enters into the hepatocytes of carbon tetrachloride-treated rats
- Development of an Experimental System for Evaluation of Stress Effect on Ethyl Alcohol Metabolism Using Radiorespirometric Analysis in Rat (Pharmacology)
- Zonal differences in gallium-67 uptakes between perivenous versus periportal regions of rat liver following carbon tetrachloride treatment
- PJ-499 Lateral E/Ea is the Most Reliable Predictor of Left Ventricular Filling Pressure in Patients with Old Myocardial Infarction(Echo/Doppler(16)(I),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Detection of liver metastases secondary to pancreatic cancer: Utility of combined helical computed tomography during arterial portography with biphasic computed tomography-assisted hepatic arteriography
- Antimicrobial-susceptible patterns of Staphylococcus aureus isolated from surgical infections : a new approach
- The Entering of Indium-111 and Iron-59 into the Hepatocytes from Partially Hepatectomized Rats Differ from That of Gallium-67(Biochemistry/Molecular Biology)
- Effect of Restraint and Footshock Stress and Norepinephrine Treatment on Gastric Emptying in Rats
- Adenocarcinoma of the Minor Duodenal Papilla : Report of a Case
- Statistical Timing Analysis Considering Clock Jitter and Skew due to Power Supply Noise and Process Variation
- Estimation of mandibular growth using biological markers of bone metabolism in urine
- A Possible Mechanism for the Exchange of Transferrin- ^Ga Complex to Heparan Sulfate- ^Ga Complex
- Development of an Experimental System for Evaluation of the Effect of Stress on Intestinal Motility Using a Radionuclide, ^Cr, in the Rat
- Experimental and Thermodynamic Studies of the Fe–Si Binary System
- Experimental and Thermodynamic Studies of the Fe-Si Binary System