Changes in Ingestive Behavior Induced by Intracranial Injection of Spermine
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概要
- 論文の詳細を見る
Effect of intracranial injection of spermine on feeding and drinking behavior was studied in rats. A significant and long-term suppression of feeding and drinking behavior appeared when 30 nmol/hemisphere of spermine was bilaterally injected into the lateral hypothalamic area, substantia nigra or ventral noradrenergic bundle. Micro-injected spermine into the medial amygdaloid nucleus produced a weak and short-time but significant suppression of ingestive behavior. On the other hand, a significant increase in feeding and drinking behavior was observed when spermine was injected into the ventromedial hypothalamic nucleus. These results suggest that spermine inhibits neuronal activity of all the brain regions studied here.
- 公益社団法人日本薬学会の論文
著者
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KOHNO Hiroyuki
Department of Oncologic Pathology, Kanazawa Medical University
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SAKURADA Tsukasa
Department of Biochemistry, Daiichi College of Pharmaceutical Sciences
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KISARA Kensuke
Department of Pharmacology, Tohoku College of Pharmacy
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Sakurada Tsukasa
Department Of Biochemistry Daiichi College Of Pharmaceutical Sciences
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Sakurada Tsukasa
Department Of Radiopharmacy:department Of Pharmacology Tohoku College Of Pharmacy
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Sakurada Tsukasa
東北薬科大学
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Kisara Kensuke
Department Of Radiopharmacy:department Of Pharmacology Tohoku College Of Pharmacy
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Kisara Kensuke
東北薬科大学
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Sakurada T
Daiichi Coll. Pharmaceutical Sci. Fukuoka
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Sato Takumi
東北薬科大学 薬理
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Kisara Kensuke
Center For Laboratory Animal Science And Department Of Pharmacology Tohoku College Of Pharmacy
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Kohno Hiroyuki
Department Of Radiopharmacy:department Of Pharmacology Tohoku College Of Pharmacy
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Kohno Hiroyuki
Department Of Chemistry Faculty Of Science Science University Of Tokyo
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Kisara Kensuke
Department Of Pharmacology Tohoku College Of Pharmacy
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KISARA Kensuke
Department of Chemical Pharmacology Tohoku College of Pharmacy
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KOHNO Hiroyuki
Department of Chemical Pharmacology, Tohoku College of Pharmacy
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