Studies on the Granulation Process of Granules for Tableting with a High Speed Mixer. I. Physical Properties of Granules for Tableting
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概要
- 論文の詳細を見る
Several kinds of theophylline granules were prepared by monitoring the power consumption of a high speed mixer while compressing them into tablets. The physical properties of the granules and their tablets were evaluated in order to investigate the optimal physical properties and granulation conditions for tableting. As a result, the granule consisting of a mixture of small agglomerates and bulk powder of similar sizes demonstrated the most favorable physical properties for tableting. Its granulation end point was at the end above first small peak of the power consumption curve.
- 社団法人日本薬学会の論文
- 1994-04-15
著者
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湯浅 宏
東京薬科大学
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金谷 芳雄
東京薬科大学
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湯浅 宏
東京薬科大学 薬学部製剤設計学教室
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湯浅 宏
Tokyo College of Pharmacy
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金谷 芳雄
Tokyo College of Pharmacy
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白石 達郎
Hoechst Japan Co., Ltd.,
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近藤 修二
Hoechst Japan Co., Ltd.,
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近藤 修二
Hoechst Japan Co. Ltd.
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Kanaya Yoshio
Laboratory Of Medical & Pharmaceutical Technology School Of Pharmacy Tokyo University Of Pharmac
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Kanaya Yoshio
Tokyo College Of Pharmacy
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Shiraishi Takayuki
Laboratoiy Of Health Chemistry Faculty Of Pharmaceutical Science Niigata University Of Pharmacy And
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Kondo S
Kyoritsu Coll. Pharmacy Tokyo Jpn
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白石 達郎
Hoechst Japan Co. Ltd.
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