Nature of Mechanoradical Formation of Substituted Celluloses as Studied by Electron Spin Resonance

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概要

• 論文の詳細を見る

• Mechanically induced free radical (mechanoradical) formation of several substituted celluloses such as carboxylmethyl cellulose, chitin, and chitosan was studied based on electron-spin resonance (ESR) in comparison with those of plasma-induced radicals. Room temperature ESR spectra had multicomponent spectra and were different in pattern from each other. The mechanoradical concentration gradually decreased after reaching the maximum value in each substituted polysaccharide, accompanied by a decrease in molecular weight in the course of vibratory milling. One of the most intriguing facts is that the component radicals are all glucose-based radicals as in the case of plasma irradiation, although it is known that mechanoradicals are formed by 1,4-glucosidic bond cleavage of polysaccharides.

• 公益社団法人日本薬学会の論文
• 2004-03-01

著者

• 葛谷 昌之

  Matsuyama Univ. Ehime Jpn

• Kondo S

  Hoechst Japan Co. Ltd.

• 近藤 修二

  Hoechst Japan Co. Ltd.

• Kondo Shigemi

  Nissui Pharmaceutical Co. Ltd.

• KONDO Shin-ichi

  Laboratory of Pharmaceutical Physical Chemistry, Gifu Pharmaceutical University

• SASAI Yasushi

  Laboratory of Pharmaceutical Physical Chemistry, Gifu Pharmaceutical University

• 笹井 泰志

  岐阜薬科大学

• KUZUYA Masayuki

  Laboratory of Pharmaceutical Physical Chemistry, Gifit Pharmaceutical University

• YAMAUCHI Yukinori

  Laboratory of Pharmaceutical Physical Chemistry, Gifu Pharmaceutical University

• Yamauchi Yuji

  Exploratory Medicinal Sciences Pgrd Nagoya Laboratories Pfizer Pharmaceuticals Inc.

• Kondo S

  Ntt Photonics Laboratories

• Kondo S

  Kyoritsu Coll. Pharmacy Tokyo Jpn

• Kondo Shin-ichi

  Dep. Of Pharmaceutical Physical Chemistry Gifu Pharmaceutical Univ.

• Kuzuya Masayuki

  Laboratory Of Pharmaceutical Physical Chemistry Gifu Pharmaceutical University

• Yamauchi Y

  Osaka Univ. Osaka Jpn

• Sasai Yasushi

  Gifu Pharmaceutical Univ. Gifu Jpn

• 近藤 伸一

  岐阜薬科大学

• Kondo Shin-ichi

  Laboratory of Pharmaceutical Physical Chemistry, Department of Drug Delivery Technology and Science, Gifu Pharmaceutical University

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