Continuous Production of an Antibiotic Polypeptide (Nisin) by Lactococcus lactis Using a Bioreactor Coupled to a Microfiltration Module
スポンサーリンク
概要
- 論文の詳細を見る
The continuous production of nisin, an antibiotic polypeptide, by Lactococcus lactis in a bioreactor system coupled to a microfiltration module is described. Nishin productivity with respect to both cultivation time (ND) and the quantity of glucose consumed (ND/S_f) in continuous production was enhanced by maintaining a low concentration of lactic acid in the broth. A maximum ND of 7.80×10^4U・l^<-1>・h^<-1> and ND/S_f of 5.20×10^3U・g<-1>・h<-1> were obtained when the glucose concentration in the feed medium was 15 g/l. These values represent about 4.1- and 4.5-fold increases, respectively, over those obtained in batch culture.
- 社団法人日本生物工学会の論文
- 1994-06-25
著者
-
Taniguchi Masayuki
Department of Materials Science and Technology, Niigata University
-
FUJII Michihiro
Department of Chemical Engineering, Faculty of Engineering, Niigata University
-
Taniguchi M
Fac. Engineering Niigata Jpn
-
Taniguchi M
Department Of Material Science And Technology Faculty Of Engineering
-
Taiyouji Mayumi
Gaduate School Of Science And Technology Niigata University:food Research Center Niigata Agricultura
-
Taniguchi Masayuki
Department Of Materials Science And Technology Niigata University
-
Hoshino Kazuhiro
Department Of Materials Systems Engineering And Life Science Toyama University
-
Tanaka Mitsuo
Department Of Food Science And Technology Faculty Of Agriculture Kyoto University
-
HOSHINO KAZUHIRO
(Present address)Department of Chemical and Biochemical Engineering, Faculty of Engineering, Toyama
-
URASAKI HIROYUKI
Department of Chemistry and Chemical Engineering, Faculty of Engineering, Niigata University
-
Fujii Michihiro
Department Of Chemistry And Chemical Engineering Niigata University
-
Fujii Michihiro
Department Of Chemical Engineering Faclty Of Engineering Niigata University
-
Taniguchi Masayuki
Department Of Cardiology Jikei University School Of Medicine Daisan Hospital
-
Hoshino Kazuhiro
Section Of Functional Molecule Production Systems Field Of Nano And Functional Material Sciences Gra
-
Urasaki Hiroyuki
Department Of Chemistry And Chemical Engineering Faculty Of Engineering Niigata University
-
Takahashi Masafumi
Department of Materials Science and Technology, Niigata University
関連論文
- Growth-inhibition of hiochi bacteria in namazake (raw sake) by bacteriocins from lactic acid bacteria(BREWING AND FOOD TECHNOLOGY)
- Evaluation of Fungal Pretreatments for Enzymatic Saccharification of Rice Straw
- Effect of steam explosion pretreatment on treatment with Pleurotus ostreatus for the enzymatic hydrolysis of rice straw(ENVIRONMENTAL BIOTECHNOLOGY)
- Effects of Spironolactone During an Angiotensin II Receptor Blocker Treatment on the Left Ventricular Mass Reduction in Hypertensive Patients With Concentric Left Ventricular Hypertrophy
- Additive Effects of Spironolactone to Angiotensin II Receptor Blocker Monotherapy on Aldosterone Breakthrough in Patients with Essential Hypertension
- Effects of Bradykinin on Cardiovascular Remodeling in Renovascular Hypertensive Rats
- Production of Bifidogenic Growth Stimulator by Co-cultivation of Propionibacterium shermanii and Lactobacillus Strain Using Lactose as a Carbon Source
- Production of Extracellular Bifidogenic Growth Stimulator(BGS) from Propionibacterium shermanii Using a Bioreactor System with a Microfiltration Module and an On-line Controller for Lactic Acid Concentration(BIOCHEMICAL ENGINEERING)
- Production of Extracellular Bifidogenic Growth Stimulator by Anaerobic and Aerobic Cultivations of Several Propionibacterial Strains(BIOCHEMICAL ENGINEERING)
- OJ-052 Holter Parameters for Optimal Ventricular Rate Control in Patients with Chronic Atrial Fibrillation(OJ09,ECG/Body Surface Potential Mapping/Holter (A),Oral Presentation (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Socie
- Chronobiological Analysis by Ambulatory Blood Pressure Monitoring of the Hyperbaric and Hypobaric Indexes for Evaluation of the Antihypertensive Effect of Long-Acting Nifedipine
- Continuous Culture of RPMI 8226 Human Cells
- Saccharification of Cellulose by Combined Hydrolysis with Acid and Enzyme : Studies on the Re-utilization of Cellulosic Resources (IV).
- Cellulase Productivity of Eupenicillium javanicum : Studies on the Re-utilization of Cellulosic Resources (V).
- Production of Superoxide Dismutase from Streptococcus lactis Using a Bioreactor with a Microfiltration Module(Microbiology & Fermentation Industry)
- Rapid Production of Pediococcus halophilus Salt-Tolerant Cells by a Cultivation Method Employing Gradual Increases in NaCl Concentration Using a Fermentor with a Microfiltration Module
- Development of Immobilized Metal Ion Affinity Gel : Adsorption and Desorption Properties of Metal Ions Onto and From Chelating Sepharose Fast Flow Gel
- Dissociation Equilibrium in Chelating Sepharose Fast Flow Gel
- -43-CLINICAL CHARACTERISTICS OF ACUTE MYOCARDIAL INFARCTION IN PATIENTS WITH DIABETES MELLITUS : WITH RESPECT TO THE INCIDENCE OF POWER FAILURE
- Continuous Lactic Acid Production from Raw Starch in a Fermentation System Using a Reversibly Soluble-autoprecipitating Amylase and Immobilized Cells of Lactobacillus casei(Microbiology & Fermentation Industry)
- FE-P8 Establishment of optimal conditions for extracting protein fractions inhibiting arg-gingipain from polished rice(Section IX Food Engineering)
- FE-P6 Growth-inhibitory activity of antimicrobial peptides from rice against oral pathogenic bacteria and clarification of their action mechanism(Section IX Food Engineering)
- OE-195 Effect of Beta-Blocker on Sarcoplasmic Reticulum Ca Handling and Contractility in Ca-Force-Frequency Relationship in Perfused Rat Heart(Cardiac Function, Basic/Clinical 1 (M) : OE24)(Oral Presentation (English))
- The Effect of Angiotensin Receptor Antagonist and Aldosterone Receptor Antagonist against Cardiac Hypertrophy in Renovascular Hypertensive Rat
- Treatment of Nonylphenol with Laccase in a Rotating Reactor(ENVIRONMENTAL BIOTECHNOLOGY)
- Enzymatic Oxidative Polymerization of 4-Chloroguaiacol by Laccase
- Treatment of Model Soils Contaminated with Phenolic Endocrine-Disrupting Chemicals with Laccase from Trametes sp.in a Rotating Reactor
- Evaluation of Pretreatment with Pleurotus ostreatus for Enzymatic Hydrolysis of Rice Straw(ENVIRONMENTAL BIOTECHNOLOGY)
- Production of L-Lactic Acid by Simultaneous Saccharification and Fermentation Using Unsterilized Defatted Rice Bran as a Carbon Source and Nutrient Components
- Production of a Mixture of Antimicrobial Organic Acids from Lactose by Co-Culture of Bifidobacterium longum and Propionibacterium freudenreichii
- Formation of Inclusion Complexes between Cyclodextrins and Aromatic Compounds under pressurized Carbon Dioxide
- Purification of Recombinant α-Amylase with Immuno-Affinity Chromatography Using Monoclonal Antibody
- Effective Utilization of Horseradish and Wasabi by Treatment with Supercritical Carbon Dioxide
- Synthesis of Aspartame Precursors by Enzymatic Reaction in Supercritical Carbon Dioxide(Food & Nutrition)
- Brewing of Sake from Rice and Rice-Koji Defatted by Supercritical Carbon Dioxide Treatment
- Removal of Organic Solvent from Antibiotics with Supercritical Carbon Dioxide
- Effect of Treatment with Supercritical Carbon Dioxide on Enzymatic Activity(Food & Nutrition)
- Sterilization of Microorganisms with Supercritical Carbon Dioxide(Food & Nutrition)
- Impaired Ca^ Handling in Perfused Hypertrophic Hearts from Dahl Salt-Sensitive Rats
- Effect of taurine on intracellular Ca handling and contractility (Ca-force-frequency relationship) in perfused rat hearts
- Contribution of inducible Nitric Oxide Synthase to Cardiac Function and Reperfusion Arrhythmias in Isolated Perfused Rat Heart
- Inhibition by KB-R7943 of the Reverse Mode of the Na^+/Ca^ Exchanger Reduces Ca^ Overload in Ischemic-Reperfused Rat Hearts
- Production of Bacteriocin by Staphylococcus sp. NPSI 38 in Koji Extract Medium with Rice Protein Hydrolyzate and Its Growth-inhibitory Activity against Hiochi-bacteria
- Desorption Properties of Preadsorbed Metal lons from Sodium Polyacrylate Gel
- Adsorption Properties of Metal Ions onto Sodium Polyacrylate Gel
- Preparation of a Novel Thermo-Responsive Polymer and Its Use as a Carrier for Immobilization of Thermolysin
- ADSORPTION PROPERTIES OF TRIVALENT METAL IONS ONTO HYDROLYZED POLYACRYLAMIDE GEL
- Repeated Utilization of β-Glucosidase Immobilized on a Reversibly Soluble-Insoluble Polymer for Hydrolysis of Phloridzin as a Model Reaction Producing a Water-Insoluble Product
- EFFECT OF HYDROGEN ION ON SOLVENT EXTRACTION OF COPPER(II)COMPLEX WITH BATHOCUPROINE
- Continuous Production of an Antibiotic Polypeptide (Nisin) by Lactococcus lactis Using a Bioreactor Coupled to a Microfiltration Module
- Hydrolysis of Starchy Materials by Repeated Use of an Amylase Immobilized on a Novel Thermo-Responsive Polymer
- PRODUCTION OF ETHANOL FROM RECLAIMED PAPER USING A COMBINATION OF A REVERSIBLY SOLUBLE- AUTOPRECIPITATING CELLULASE AND FLOCCULATING YEAST CELLS
- DISSOCIATION EQUILIBRIUM IN HYDROLYZED POLYACRYLAMIDE GEL ACCOMPANIED BY SWELLING AND SHRINKING
- PROPERTIES OF AMYLASE IMMOBILIZED ON A NEW REVERSIBLY SOLUBLE-INSOLUBLE POLYMER AND ITS APPLICATION TO REPEATED HYDROLYSIS OF SOLUBLE STARCH
- Continuous Ethanol Production from Raw Starch Using a Reversibly Soluble-Autoprecipitating Amylase and Flocculating Yeast Cells
- Two Cases of Transiently TSBAb-Positive Hypothyroidism Induced by Interferon-Alpha Therapy for Chronic Hepatitis C
- -0937- THE EFFECT OF HYPOXIA ON Na^+/Ca^+ EXCHANGE IN ISOLATED PERFUSED RAT HEART(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY)
- A POSSIBLE ROLE OF ATP SENSITIVE POTASSIUM CHANNEL ON CARDIAC FUNCTION DURING ISCHEMIA AND REPERFUSION IN ISOLATED PERFUSED RAT HEART
- EFFECT OF PILSICAINIDE HCL, A CLASS I c ANTI-ARRHYTHMIC AGENT, ON INTRACELLULAR Na^+, pH AND REPERFUSION ARRHYTHMIAS.
- PJ-651 Initial and Long-Term Outcomes of Sirolimus-Eluting Stents for Hemodialysis Patients(Coronary revascularization, PCI(23)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Evaluation of Fungal Pretreatments for Enzymatic Saccharification of Rice Straw
- ISCHEMIC PR. E. CONDITIONING ATTENUATES THE INCREASE IN [H^+]i, [Ca^]i, AND [Na^+]i DURING PROLONGED ISCHEMIA IN ISOLATED RAT HEARTS.
- Formation of Biodegradable Polyesters Membranes via Thermally Induced Phase Separation
- Preparation of Defatted Mustard by Extraction with Supercritical Carbon Dioxide(Food & Nutrition)
- Production of L-lactic acid by simultaneous saccharification and fermentation using unsterilized defatted rice bran as a carbon source and nutrient components
- Ethanol Production from a Mixture of Glucose and Xylose by a Novel Co-Culture System with Two Fermentors and Two Microfiltration Modules
- Ethanol Production from a Mixture of Glucose and Xylose by Co-Culture of Pichia stipitis and a Respiratory-Deficient Mutant of Saccharomyces cerevisiae
- Purification of Staphylococcal Protein A by Affinity Precipitation Using a Reversibly Soluble-Insoluble Polymer with Human IgG as a Ligand
- EFFECTS OF HIGH-AND LOW-DENSITY LIPOPROTEINS ON HEMODYNAMICS IN ISOLATED PERFUSED RAT HEART
- Acid Base Changes in Ischemic Myocardium and Intervention with Hypothermia or Bicarbonate : SYMPOSIUM ON PATHOPHYSIOLOGY IN THE EARLY STAGE OF ACUTE MYOCARDIAL INFARCTION AND ITS TREATMENT : 51th Annual Scientific Session of the Japanese Circulation Socie
- Repeated Batch Conversion of Raw Starch to Ethanol Using Amylase Immobilized on a Reversible Soluble-autoprecipitating Carrier and Flocculating Yeast Cells(Microbiology & Fermentation Industry)
- The structures of eicosapentaenoic acid (EPA) derivatives formed during accelerated stability testing of EPA ethylester
- Functional and Metabolic Properties in Hearts from Aged Spontaneously Hypertensive Rats : SYMPOSIUM ON LONG-TERM MYOCARDIAL CHANGES IN HEART DISEASES : 49th Annual Scientific Session of the Japanese Circulation Society
- ALTERATIONS IN Ca^ TRANSIENTS AND INTRA CELLULAR pH DURING ISCHEMIC CONTRACTILE FAILURE IN THE INTACT RAT HEARTS.
- Possible roles of Na^+/H^+and CI^-/HCO^-_3 exchangers in the development of Ischemia-reperfusion induced arrhythmias
- EFFECT OF ISCHEMIA ON MYOCARDIAL LIPOPROTEIN LIPASE ACTIVITY IN ISOLATED, PERFUSED RAT HEART : Cardiac Metabolism (I) : IV : 48 Annual Scientific Meeting, Japanese Circulation Society
- Poly(L-Lactic Acid) Microfiltration Membrane Formation via Thermally Induced Phase Separation with Drying
- MYOCARDIAL PROTECTIVE EFFECTS OF INTRINSIC STORAGE IN DIABETIC HEART
- Magnetization Curves for a Two-Dimensional Antiferromagnet: Cu (HCOO)_2・2(NH_2)_2CO・2H_2O
- Perindopril Reberses Myocyte Remodeling in the Hypertensive Heart
- 0156 ROLES OF Na^+/Ca^ EXCHANGER DURING ISCHEMIC PRECONDITIONING.
- Purification and Properties of Cellulases from Eupencillium javanicum : Studies on the Re-utilization of Cellulosic Resources(VII)
- Effect of Culture Conditions on Cellulase Production by Pellicularia filamentosa : Studies on the Re-utilization of Cellulosic Resources (IV).
- Some Factors Affecting Cellulose Degradation with Pellicularia filamentosa Cellulases : Studies on the Re-utilization of Cellulosic Resources (II)
- Production of Vitamin B_ by Methanol-utilizing Bacteria, Pseudomonas AM-1 and Microcyclus eburneus
- Purification and Properties of Cellulases from Pellicularia filamentosa : Studies on the Re-utilization of Cellulosic Resources(I)
- P399 CA^ -DEPENDENT FLUORESCENCE TRANSIENTS AND CONTRACTILITY DURING LOW-FLOW ISCHEMIA AND REPERFUSION IN RAT HEARTS CONTAINING FURA-2
- Relationship between Cake Structure and Membrane Pore Size in Crossflow Filtration of Microbial Cell Suspension Containing Fine Particles
- Kefiran Production by Lactobacillus kefiranofaciens under the Culture Conditions Established by Mimicking the Existence and Activities of Yeast in Kefir Grains
- Purification of Staphylococcal Protein A by Affinity Precipitation : Dissociation of Protein A from the Adsorbent with Chemical Reagents
- Poly(L-lactic acid) Microfiltration Membrane Formation via Thermally Induced Phase Separation with Drying
- Sterilization of Plasma Powder by Treatment with Supercritical Carbon Dioxide(Food & Nutrition)
- Depth Filtration of Cell Suspensions of Agglomerated Streptobacteria by Biodegradable Membranes
- Evaluation of positive interaction for cell growth between Bifidobacterium adolescentis and Propionibacterium freudenreichii using a co-cultivation system with two microfiltration modules(BIOCHEMICAL ENGINEERING)
- Kefiran Production by Lactobacillus kefiranofaciens under the Culture Conditions Established by Mimicking the Existence and Activities of Yeast in Kefir Grains
- Solvent extraction of plant pigments from leaf protein concentrate.
- Effect of Puff Cooking on Structure and Chemical Properties of Several Lignocellulosic Agrowastes
- Repeated simultaneous saccharification and fermentation of raw starch by a combination of a reversibly soluble-insoluble amylase and yeast cells.
- Two-stage membrane separation with carrier gas for ethanol-water mixtures using silicone rubber and polyimide hollow fibers.
- Repeated hydrolysis of raw starch using amylase immobilized on a reversibly soluble-insoluble carrier.