Effects of Spironolactone During an Angiotensin II Receptor Blocker Treatment on the Left Ventricular Mass Reduction in Hypertensive Patients With Concentric Left Ventricular Hypertrophy

スポンサーリンク

概要

• 論文の詳細を見る

• Background Angiotensin II receptor blockers (ARB) are now commonly used to treat hypertension because of their beneficial effects on cardiovascular remodeling. However, ARE treatment can not inhibit the left ventricular (LV) remodeling sufficiently, which may be related with aldosterone secretion. To inhibit the action of aldosterone during ARB treatment, the additional effects of an aldosterone blocker and spironolactone (SPRL) on LV hypertrophy in patients with essential hypertension was studied. Methods and Results The patients with essential hypertension were randomly divided into 2 groups; 1 group was treated with an ARB, candesartan (8mg/day), for 1 year (ARB group) and other group was treated with the ARB for the first 6 months and with the ARB plus SPRL (25mg/day) for the next 6 months (combination group). Seventy patients who underwent echocardiography every 6 months were analyzed and were also classified into 4 subgroups of LV geometric pattern according to the LV mass index (LVMI) and the relative wall thickness (RWT). The ARB treatment and the addition of SPRL significantly reduced the blood pressure, however, both treatments did not affect the LV geometry in both groups. The ARB treatment in the subgroups of concentric LV remodeling (RWT ≥0.45 and LVMI <125) and concentric LV hypertrophy (RWT ≥0.45 and LVMI ≥125) significantly reduced RWT. However, ARB treatment in all subgroups did not affect LVMI. The addition of SPRL only in the concentric LV hypertrophy subgroup significantly reduced the LVMI, despite similar changes in blood pressure. Conclusions These results indicated that the addition of SPRL treatment during the ARB treatment and conventional treatments is clinically useful to reduce the LVMI in hypertensive patients with concentric LV hypertrophy; however, does not improve the eccentric LV hypertrophy.

• 社団法人日本循環器学会の論文
• 2006-07-20

著者

• Mochizuki Seibu

  Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine

• Shimazu Yoshihisa

  Jikei University School Of Medicine

• KAWAI Makoto

  Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine

• SEKI Shingo

  Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine

• TANIGUCHI Ikuo

  Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine

• DATE Taro

  Division of Cardiology, Department of Internal Medicine, Jikei University School of Medicine

• Yoshida Satoru

  Division of Cardiology, The Jikei University School of Medicine

• 河上 牧夫

  Department Of Pathology The Jikei University School Of Medicine

• 小西 真人

  東京医科大学細胞生理学講座

• 小西 眞人

  東京医科大学細胞生理学

• 小西 真人

  東京医科大学生理第一

• 小西 真人

  東京医科大学第一生理

• Date Taro

  Division Of Cardiology Jikei University School Of Medicine And Genzyme Corporation

• Konishi M

  Department Of Physiology (i) Tokyo Medical University

• Konishi Masato

  東京慈恵会医科大学 生理学第二

• Date Taro

  Division Of Cardiology Department Of Internal Medicine The Jikei University School Of Medicine

• Taniguchi Masayuki

  Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine

• Shimizu Mitsuyuki

  Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine

• Kawai Makoto

  東京慈恵会医科大学 循環器内科

• Kawai Makoto

  Division Of Cardiology Department Of Internal Medicine The Jikei University School Of Medicine

• Date Taro

  Division Of Cardiology Department Of Internal Medicine Jikei University School Of Medicine

• Taniguchi M

  Fac. Engineering Niigata Jpn

• Taniguchi Masayuki

  Division Of Cardiology Department Of Internal Medicine The Jikei University School Of Medicine

• Taniguchi Masayuki

  Department Of Food Science And Technology Faculty Of Agriculture Kyoto University

• Taniguchi Masayuki

  Department Of Medicine The Jikei University School Of Medicine Aoto Hospital

• Mochizuki S

  Division Of Cardiology Jikei University School Of Medicine

• Mochizuki Seibu

  Division Of Cardiology Department Of Internal Medicine Jikei Univerisity School Of Medicine

• Yamashita Shogo

  Department Of Cardiology Jikei University School Of Medicine

• Taniguchi Masayuki

  Gaduate School Of Science And Technology Niigata University:food Research Center Niigata Agricultura

• Shimizu Mitsuyuki

  Division Of Cardiology Department Of Internal Medicine Jikei University School Of Medicine

• Yoshida Satoru

  Division Of Cardiology Department Of Internal Medicine The Jikei University School Of Medicine

• Seki Shengo

  Division Of Cardiology Department Of Internal Medicine The Jikei University School Of Medicine

• Seki Shingo

  Devision Of Cardiology Jikei University Aoto Hospital

• Taniguchi Ikuo

  Division Of Cardiology Department Of Internal Medicine The Jikei University School Of Medicine

• Taniguchi Ikuo

  Division Of Clinical Pharmacology And Therapeutics Department Of Internal Medicine Jikei University

• Yoshida Satoru

  Department Of Cardiology Jikei University Of Medicine

• Yoshida Satoru

  Division Of Cardiology The Jikei University School Of Medicine

• Yoshida Satoru

  Division Of Cardiology Department Of Internal Medicine Jikei University School Of Medicine

• Shimizu Mitsuyuki

  Division Of Cardiology Department Of Internal Medicine The Jikei University School Of Medicine Kashi

• Seki Shingo

  Division Of Cardiology Department Of Internal Medicine The Jikei University School Of Medicine

• Yoshida Satoru

  Division Of Cardiology Department Of Internal Medicine

• Shimizu Mitsuyuki

  Division Of Cardiology Department Of Internal Medicine The Jikei University School Of Medicine Kashi

• Shimizu Mitsuyuki

  Third Department Of Internal Medicine The Jikei University School Of Medicine

• Shimizu Mitsuyuki

  Division Of Cardiology Department Of Internal Medicine The Jikei University School Of Medicine Kashi

関連論文

• High Incidence of Repeat Anginal Attacks Despite Treatment With Calcium-Channel Blockers in Patients With Coronary Spastic Angina(Ischemic Heart Disease)
• Predictors of Target Lesion Revascularization and Documented Stent Thrombosis Beyond 30 Days After Sirolimus-Eluting Stent Implantation : Retrospective Analysis in Consecutive 1,070 Angiographic Follow-up Lesions
• PJ-268 Predictors of Angiographic Target Lesion Revascularization within 1 Year after Successful Sirolimus-Eluting Stent (Cypher) Implantation(Restenosis basic/clinical-4, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-361 Impact of Sirolimus-eluting Coronary Stent (Cypher) on binary restenosis and target lesion revascularization in the RCA Ostiual Lesion(Coronary revascularization, PCI-16 (IHD) PJ61,Poster Session (Japanese),The 70th Anniversary Annual Scientific Me
• FRS-061 Clinical and Angiographic Follow-up after Primary Stenting with Sirolimus-Eluting Stent (Cypher) in Acute Myocardial Infarction(Strategies to Acute Myocardial Infarction-1 (IHD) FRS13,Featured Research Session,The 70th Anniversary Annual Scientifi
• PJ-361 Impact of Sirolimus-eluting Coronary Stent (Cypher) on binary restenosis and target lesion revascularization in the RCA Ostiual Lesion(Coronary revascularization, PCI-16 (IHD) PJ61,Poster Session (Japanese),The 70th Anniversary Annual Scientific Me
• FRS-061 Clinical and Angiographic Follow-up after Primary Stenting with Sirolimus-Eluting Stent (Cypher) in Acute Myocardial Infarction(Strategies to Acute Myocardial Infarction-1 (IHD) FRS13,Featured Research Session,The 70th Anniversary Annual Scientifi
• Telmisartan predominantly suppresses cardiac fibrosis, rather than hypertrophy, in renovascular hypertensive rats
• PJ-751 Impact of Smoking on Restenosis after Percutaneous Coronary Intervention (PCI) with Bare Metal Stents (BMS)(PJ126,Smoking/Alcohol/Life Style (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• PJ-565 Aging-related Regional Inhomogeneities in Macrophage Infiltration and Interstitial Fibrosis in Rat Atria(PJ095,Arrhythmia, Others (Basic) 2 (A),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• PJ-479 Additional Evaluation for Ischemia is Required to Perform CAG after MSCT(PJ081,CT/MRI (Coronary/Vascular) 3 (I),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• PJ-435 Promotion of Macrophage Infiltration and Interstitial Fibrosis in Diabetic Rat Atria(PJ073,Arrhythmia, Others (Basic) 1 (A),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• PJ-387 Angiographic outcome after Primary Stenting to ST-Segment Elevation Acute Myocardial Infarction with Sirolimus- versus Paclitaxel-Eluting Stents(PJ065,ACS/AMI (Clinical/Treatment) 3 (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting
• PJ-294 Fibrillatory Cycle Length Prolongation on Surface Electrocardiogram by Pulmonary Vein Isolation : Role of Pulmonary Vein in Persistent Atrial Fibrillation Patients(PJ050,Arrhythmia, Others (Clinical/Diagnosis/Treatment) 4 (A),Poster Session (Japane
• PJ-167 Factors for Long Term Hospitalization with Chronic Heart Failure(PJ028,Cardiovascular Pharmacology (Basic), Cost-health care system/DPC/Laws (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• PJ-153 Lower Prevalence of Dissociated Activity in Isolated Pulmonary Veins according to the Progression of Atrial Fibrillation(PJ026,Atrial/Supraventricular Arrhythmia (Clinical/Treatment) 1 (A),Poster Session (Japanese),The 73rd Annual Scientific Meetin
• PE-373 Early Definite Stent Thrombosis of Drugs-Eluting Stents under the First Chosen Thienopyridine Antiplatelet (Ticlopidine versus Clopidogrel) : A Retrospective non-Randomized Study(PE063,Coronary Revascularization, PCI (DES) 5 (IHD),Poster Session (E
• PE-290 Impact of Prolongation of Atrial Fibrillatory Cycle Length on Catheter Ablation Results in Long-Lasting Persistent Atrial Fibrillation(PE049,Atrial/Supraventricular Arrhythmia (Clinical/Treatment) 2 (A),Poster Session (English),The 73rd Annual Scie
• PE-256 Regional Differences in Removal of Atrial Natriuretic Polypeptide in the Human Lungs(PE043,Heart Failure (Biomarker) 1 (M),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• PE-138 Impact of Paclitaxel-Eluting Stent on Predictors of Target Lesion Revascularization of Sirolimus-Eluting Stent : Retrospective Estimation in 2678 Angiographic Followed-up Lesions(PE023,Coronary Revascularization, PCI (DES) 3 (IHD),Poster Session (E
• PE-102 Aldosterone in the Human Atrial Fibrillation Heart : A Possible Role of Aldosterone in Generating Atrial Fibrillation after Catheter Ablation(PE017,Arrhythmia, Others (Clinical/Diagnosis/Treatment) 2 (A),Poster Session (English),The 73rd Annual Sci
• Inhibitory Effect of Valsartan Against Progression of Left Ventricular Dysfunction After Myocardial Infarction : T-VENTURE Study
• Beta-Adrenergic Stimulation Failed to Regulate Intracellular Ca^ Concentration and Isometric Tension in SERCA2a Overexpressing Heart
• OE-103 Clinical Predictors of Termination and Clinical Outcome of Catheter Ablation for Persistent Atrial Fibrillation(OE18,Atrial Fibrillation/Supraventricular Arrhythmia: Treatment (A),Oral Presentation (English),The 73rd Annual Scientific Meeting of Th
• OE-102 Presence of Chronic Kidney Disease is Associated with Higher Atrial Fibrillation Recurrence after Pulmonary Vein Isolation(OE18,Atrial Fibrillation/Supraventricular Arrhythmia: Treatment (A),Oral Presentation (English),The 73rd Annual Scientific Me
• FRS-010 Non-invasive Vectorcardiographic Evaluation of Pulmonary Veinatrial Reconnection after Pulmonary Vein Isolation for Atrial Fibrillation(FRS2,Novel Strategy for Atrial Fibrillation (A),Featured Research Session (English),The 73rd Annual Scientific
• 6 Hybrid Therapy of Bepridil and Catheter Ablation: Practical Strategy to Conquer Chronic Atrial Fibrillation with Supplementary Low-dose Antiarrhytymic Treatment(Latest Challenge of Ablation for Chronic Atrial Fibrillation-Where are We Now and Where are
• Effects of Spironolactone During an Angiotensin II Receptor Blocker Treatment on the Left Ventricular Mass Reduction in Hypertensive Patients With Concentric Left Ventricular Hypertrophy
• Additive Effects of Spironolactone to Angiotensin II Receptor Blocker Monotherapy on Aldosterone Breakthrough in Patients with Essential Hypertension
• Effects of Bradykinin on Cardiovascular Remodeling in Renovascular Hypertensive Rats
• OE-345 Diagnostic Accuracy of Dual-Source CT Cardiac Imaging in Patients with Coronary Artery Disease(CT/DSA(02)(I),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• Renal Insufficiency is Related to Painless Myocardial Infarction
• FRS-015 Genetic Modulation of Ca^ Uptake Sarcoplasmic Reticulum Does Not Affect Maximal Ca^ Content and Ca^ Leakage in Mouse Myocardium(Cardiac Function "Ventricular Mechanics and Calcium Handling", The 71st Annual Scientific Meeting of the Ja
• OJ-296 Overexpression of SERCA2a and Sarcolipin Does Not Affect Maximal Ca^ Content and Ca^ Leakage of Sarcoplasmic Reticulum in Mouse Myocardium(Cardiac function, basic/clinical-2 (M) OJ50,Oral Presentation (Japanese),The 70th Anniversary Annual
• A Directly Measurement of SR Ca^ Content in Mouse Ventricular Muscle : Not Vesicular SR(Cardiac Function, Basic/Clinical 1 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Antecedent Thrombolytic Therapy Followed by Planned Rescue PCI for Acute Myocardial Infarction, Compared with Primary PCI
• Pulmonary Embolism and Deep Vein Thrombosis Complicating Acute Aortic Dissection during Medical Treatment
• Combined Treatment With Valsartan and Spironolactone Prevents Cardiovascular Remodeling in Renovascular Hypertensive Rats
• Effect of Amlodipine on Vascular Responses After Coronary Stenting Compared With an Angiotensin-Converting Enzyme Inhibitor
• PE-046 Secondary Cardiac Events in 1118 Patients with Old Myocardial Infarction Revascularized by Sirolimus Eluting Stent and Bare Metal Stents(PE008,Coronary Revascularization, PCI (DES) 1 (IHD),Poster Session (English),The 73rd Annual Scientific Meeting
• Angiographic and Clinical Outcomes After Sirolimus-Eluting Stent Implantation to De Novo Ostial Lesion of the Right Coronary Artery : A Retrospective Study
• PJ-580 Impact of Long-term Continuous Nitrates on Secondary Cardiac Events in Revascularized Old Myocardial Infarction(Acute myocardial infarction, clinical(diagnosis/treatment)(11)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the J
• OE-248 Early Definite Stent Thrombosis after Successful Stenting with Bare-Metal, Sirolimus- and Paclitaxel-Eluting Stents : A High-Volume Single Center Study(Coronary revascularization, PCI(02)(IHD),Oral Presentation(English),The 72nd Annual Scientific M
• 3 Effect of valsartan administration in Japanese women with hypertension and cardiovascular diseases : Subanalysis results by gender from the Jikei Heart Study(Late Breaking Clinical Trials II,Special Program,The 72nd Annual Scientific Meeting of the Japa
• 2 Effect of valsartan in Japanese population with hypertension alone and coronary heart disease : Results from the Jikei Heart Study(Late Breaking Clinical Trials II,Special Program,The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-705 Usefulness of Inferior Vena Cava Filter for Prevention of Pulmonary Embolism in Patients with Deep Vein Thrombosis(Pulmonary circulation-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-560 15-Deoxy-Deltal2, 14-Prostaglandin-J_2 Alleviates Glucocorticoid-Induced ACE Gene Expression by Suppression of 11 β-Hydroxysteroid Dehydrogenase Type 1 Expression in Cardiac Fibroblasts(Cardiovascular pharmacology, basic/clinical-5, The 71st Annual
• Effects of Eplerenone and Salt Intake on Left Ventricular Remodeling after Myocardial Infarction in Rats
• Prevalence, Morphological and Electrophysiological Characteristics of Confluent Inferior Pulmonary Veins in Patients With Atrial Fibrillation
• Significantly lower incidence of early definite stent thrombosis of drug-eluting stents after unrestricted use in Japan using ticlopidine compared to western countries using clopidogrel : A retrospective comparison with western mega-studies
• Usefulness of a 6 Fr Right Judkins Catheter for Mechanically Extracting a Massive Intracoronary Thrombus From an Ectasic Right Coronary Artery : A report on two different cases of thrombectomy
• PE-519 Association of Serum Uric Acid with B-type Natriuretic Peptide and Cardiac Hypertrophy in Essential Hypertensive Patients(Hypertension, clinical-08, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PE-568 The First-Responder Automated External Defibrillator (AED) Program for In-hospital Emergency(Emergency care-3 (H) PE98,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• PE-490 Association of Heart Rate with Brain Natriuretic Peptide and Cardiac Function in Untreated Hypertensive Patients(Hypertension, clinical-5 (H) PE82,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation S
• PE-403 Brain Natriuretic Peptide is a Useful Marker for Anti-hypertensive Effect in Hypertensive Patients with Normal Systolic Function(Hypertension, clinical-6 (H) PE68,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japane
• PE-354 Impact of Body Mass Index on Brain Natriuretic Peptide and Cardiac Function in Essential Hypertensive Patients(Diabetes/Obesity/Metabolic syndrome-7 (H) PE59,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Ci
• PJ-362 Results of 10 Bare Metal Stents Benchmark Test(Coronary revascularization, PCI-16 (IHD) PJ61,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• 1 Long-term Follow-up Results of Ca Antagonist Therapy in Vasospastic Angina Pectoris(How Long Should We Treat the Patients with Vasospastic Angina with Calcium Channel Blockers?,Roundtable Discussion 8 (RT8) (IHD),The 70th Anniversary Annual Scientific M
• PJ-266 A Novel Quantitative Analysis of Left Ventricular Dyssynchrony Based on Regional Count Profile Curve Derived from ECG Gated Myocardial SPECT(Nuclear cardiology-7 (I) PJ45,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of t
• Chronobiological Analysis by Ambulatory Blood Pressure Monitoring of the Hyperbaric and Hypobaric Indexes for Evaluation of the Antihypertensive Effect of Long-Acting Nifedipine
• Brain Natriuretic Peptide as an Indicator for Severity of Essential Hypertensive Patients(Hypertension, Clinical 3 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Deteriorative Effect of Smoking on Target Lesion Revascularization After Implantation of Coronary Stents With Diameter of 3.0 mm or Less
• PJ-296 Atrial Septal Pacing Shows Better Outcome than Atrial Appendage Pacing for Long-Term in Patients with Bradycardia-Tachycardia Syndrome(Arrhythmia, therapy-20, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Regional angiogram of the inferior right atrial isthmus in patients with common atrial flutter
• The presence of slow conduction zone in the common atrial flutter circuit
• PE-509 Impact of Early Successful Reperfusion with PercuSurge on Salvage in Anterior and Inferior Myocardial Infarction Studied with TL/BMIPP Dual SPECT(Nuclear cardiology-2 (I) PE86,Poster Session (English),The 70th Anniversary Annual Scientific Meeting
• Myocardial Susceptibility to Ischemia and the Cardioprotective Effect of Ischemic Preconditioning on Ischemia/Reperfusion Injury in Streptozotocin Induced Diabetic Rats (Diabetes/Obesity 7 (H), The 69th Annual Scientific Meeting of the Japanese Circulatio
• OJ-042 Attenuated Insulin Sensitivity Is Involved in the Deterioration of Cardioprotective Effect of Ischemic Preconditioning(Diabetes/Obesity 1 (H) : OJ5)(Oral Presentation (Japanese))
• Differential Impact of Smoking on Target Lesion Revascularization after Balloon Angioplasty and Stenting to Ischemic Heart Diseases
• PJ-256 Impaired Post-Ischemic Cardiac Function and Cytoplasmic Ca^ Overload in Hearts from Type 2 Diabetic db/db Mice(Myocardial ischemia/reperfusion, basic/clinical-4, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-613 Clinical Significance of Brain Natriuretic Peptide Level in Essential Hypertensive Patients(Hypertension, Basic and Clinical (H) : PJ103)(Poster Session (Japanese))
• OE-195 Effect of Beta-Blocker on Sarcoplasmic Reticulum Ca Handling and Contractility in Ca-Force-Frequency Relationship in Perfused Rat Heart(Cardiac Function, Basic/Clinical 1 (M) : OE24)(Oral Presentation (English))
• What is an Important Factor for the late Left Ventricular Remodeling? (Old Myocardial Infarction/Remodeling 2 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Use of Tetanus to Investigate Myofibrillar Responsiveness to Ca^ in Isolated Mouse Ventricular Myocytes
• Hypercholesterolemia Induces Left Ventricular Hypertrophy and Fibrosis Via Increase of Aldosterone Biosynthesis(Lipid Disorders 2 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• The Inhibitory Effect of Eplerenone on Left Ventricular Remodeling after Myocardial Infarction Diminishes in Low Salt Conditions(Heart Failure, Basic 3 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Impaired Ca^ Handling in Perfused Hypertrophic Hearts from Dahl Salt-Sensitive Rats
• Effect of taurine on intracellular Ca handling and contractility (Ca-force-frequency relationship) in perfused rat hearts
• Contribution of inducible Nitric Oxide Synthase to Cardiac Function and Reperfusion Arrhythmias in Isolated Perfused Rat Heart
• Inhibition by KB-R7943 of the Reverse Mode of the Na^+/Ca^ Exchanger Reduces Ca^ Overload in Ischemic-Reperfused Rat Hearts
• PE-321 Identification of ZIP Kinase as the Unique Vascular Smooth Muscle Myosin Phosphatase-associated Kinase(Vascular smooth muscles-2 (H) PE54,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-202 Associations between the Appearance of Atrial Arrhythmia and Apnoeic Events/Arousal from Sleep in Patients with Sleep Apnea Syndrome(Arrhythmia, diagnosis/pathophysiology/EPS-12, The 71st Annual Scientific Meeting of the Japanese Circulation Societ
• PJ-041 Reduced Apelin Levels are Recovered by Pulmonary Vein Isolation in Patients with Atrial Fibrillation(Arrhythmia, diagnosis/pathophysiology/EPS-09, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PE-283 Recurrence of Atrial Fibrillation after Two Different Therapies in the Patients with Bradycardia-Tachycardia Syndrome(Arrhythmia, therapy-12, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PE-280 Incidence of Residual Septal Defects after Trans-septal Puncture for Pulmonary Vein Isolation Procedures(Arrhythmia, therapy-12, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• FRS-020 Prevalence of Thromboembolic Events after Pulmonary Vein Isolation for the Treatment of Atrial Fibrillation(Arrhythmia (clinical) ; Ablation of Atrial Fibrillation, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Common Trunk of the Inferior Pulmonary Veins in a Patient with Paroxysmal Atrial Fibrillation
• PJ-567 Prospective Randomized Study on the Prevention of Restenosis After PCI by Oral Angiotensin II Receptor Blocker (ARB) Therapy(Restenosis after Angioplasty, Basic/Clinical 7 (IHD) : PJ95)(Poster Session (Japanese))
• Effect of Continuous ATP Injection on Human Hemodynamics
• Cross-Bridge-Dependent Change in Ca^ Sensitivity is Involved in the Negative Inotropic Effect of Nifedipine in Aequorin-Injected Ferret Ventricular Muscles
• PE-209 Usefulness of IVUS-marking Technique for DES Implantation to Ostium of LAD(Coronary revascularization, PCI-12 (IHD) PE35,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• OE-296 Cortisol Augments Connective Tissue Growth Factor Gene Expression through Glucocorticoid Receptor in Cardiac Fibroblasts(Cardiovascular pharmacology, basic/clinical-1 (H) OE50,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeti
• The Effects of Pravastatin on β-Adrenergic Receptor-G Protein-Adenylyl Cyclase System in Isoproterenol-lnduced Cardiomyopathy
• Clinical Significance of B-Type Natriuretic Peptide in the Assessment of Untreated Hypertension
• The DD Genotype of Angiotensin Converting Enzyme Polymorphism is a Risk Factor for Coronary Artery Disease and Coronary Stent Restenosis in Japanese Patients
• Segmental Pulmonary Vein Antrum Isolation Using the "Large-Size" Lasso Catheter in Patients With Atrial Fibrillation
• Mitral Regurgitation Disappearance after Cibenzoline Treatment in a Patient with Hypertrophic Obstructive Cardiomyopathy
• Fenofibrate Effectively Reduces Remnants, and Small Dense LDL, and Increases HDL Particle Number in Hypertriglyceridemic Men : A Nuclear Magnetic Resonance Study
• PE-422 Abnormal In Vivo Metabolism of ApoB-100 and HDL Apolipoproteins in Type III Hyperlipidemia(Lipid Disorders 3 (IHD) : PE72)(Poster Session (English))
• PJ-548 Cardioprotective Function of Hypoxic Inducible Factor-1α Against Hypoxia-Reoxygenation Injury : Potential Mechanism of Hypoxic Preconditioning(Myocardial Ischemia-Reperfusion, Basic and Clinical 4 (M) : PJ92)(Poster Session (Japanese))

もっと見る 閉じる

スポンサーリンク