Functional and Metabolic Properties in Hearts from Aged Spontaneously Hypertensive Rats : SYMPOSIUM ON LONG-TERM MYOCARDIAL CHANGES IN HEART DISEASES : 49th Annual Scientific Session of the Japanese Circulation Society
スポンサーリンク
概要
- 論文の詳細を見る
The effect of long-term pressure overload on myocardial functional and metabolic alterations was instigated in hearts from spontaneously hypertensive rats of 16 weeks (young SHR) and 44 weeks (aged SHR) and age matched normotensive Wistar Kyoto strain rats (young WKY, aged WKY). The hearts were perfused by working heart mode and whole heart ischemia was induced by one-way valve. Following 20 min of ischemia, the hearts were reperfused for 30 min. The heart-body weight ratio in both SHR groups was significantly higher than in the respective age-matched WKY groups. Coronary flow relative to heart weight in both SHR groups was significantly lower than that of the respective age-matched WKY during both preischemic and reperfused periods. There was no significant difference in the recovery rate of cardiac output between young and aged WKY, whereas the young and aged SHR revealed significantly less recovery than their respective age-matched WKY. Tissue creatine phosphate and energy charge in both aged groups were significantly lower than in the young groups. These results indicate that long-term pressure overload increases susceptibility to ischemia and decreases the myocardial reserve presumably resulting from relative ischemia, whereas deterioration was minimal in the normotensive aged rat heart.
- 社団法人日本循環器学会の論文
- 1986-10-20
著者
-
Mochizuki Seibu
Department of Cardiology, The Jikei University School of Medicine
-
NAGANO MAKOTO
Department of Gene Science, BML, Inc.
-
Taniguchi Masayuki
Department of Materials Science and Technology, Niigata University
-
TAKAHASHI Kaoru
Department of Applied Physics, Tokyo University of Agriculture and Technology
-
Nagai Makoto
Division Of Cardiology Department Of Internal Medicine The Jikei University School Of Medicine
-
Nagano M
Department Of Medicine Jikei Aoto Hospital
-
Nagano Makoto
Department Of Advanced Medical Technology And Development Bml Inc.
-
MAENO Hiroshi
Department of Internal Medicine, The Jikei University, School of Medicine, Aoto Hospital
-
Maeno Hiroshi
Department Of Medicine The Jikei University School Of Medicine Aoto Hospital
-
Maeno Hiroshi
Department Of Internal Medicine The Jikei University School Of Medicine Aoto Hospital
-
Taniguchi Masayuki
Division Of Cardiology Department Of Internal Medicine The Jikei University School Of Medicine
-
Taniguchi Masayuki
Department Of Medicine The Jikei University School Of Medicine Aoto Hospital
-
Mochizuki Seibu
Department Of Cardiology Jikei University School Of Medicine
-
Nagano M
Division Of Cardiology Department Of Internal Medicine The Jikei University School Of Medicine
-
Takahashi K
Department Of Medicine The Jikei University School Of Medicine Aoto Hospital
-
Nagano Makoto
Department Of Internal Medicine Aoto Hospital Jikei University School Of Medicine
-
YABE Hiroyuki
Department of Medicine, The Jikei University School of Medicine, Aoto Hospital
-
KUDO Tomoko
Department of Medicine, The Jikei University School of Medicine, Aoto Hospital
-
Kudo Takashi
Department Of Medicine The Jikei University School Of Medicine Aoto Hospital
-
Taniguchi Masayuki
Department Of Cardiology Jikei University School Of Medicine Daisan Hospital
-
Yabe Hiroyuki
Department Of Medicine The Jikei University School Of Medicine Aoto Hospital
-
Takahashi Kaoru
Department Of Applied Physics Tokyo University Of Agriculture And Technology
-
Maeno Hiroshi
Department Of Internal Medicine Jikei Univ. School Of Medicine
-
Mochizuki Seibu
Departement Of Cardiology Jikei University School Of Medicine
関連論文
- Evaluation of Fungal Pretreatments for Enzymatic Saccharification of Rice Straw
- PE-007 Angiographic Target Lesion Revascularization within 1 Year after Emergent Stenting with Sirolimus-Eluting Stent for Acute Myocardial Infarction(Acute myocardial infarction, clinical (diagnosis/treatment)-4, The 71st Annual Scientific Meeting of the
- FRS-002 Impact of Distal Protection with PercuSurge GaurdWire Device on In-hospital Mortality in Patients with ST-elevated Acute Myocardial Infarction(Acute Coronary Syndrome, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Documented Subacute Stent Thrombosis Within Thirty Days After Stenting With Sirolimus-Eluting Stent (Cypher^[○!R]) for Acute Myocardial Infarction : A Japanese Single Center Retrospective Non-Randomized Study
- OJ-143 Differential Predictors for Binary Restenosis between Bare Metal Stents and Sirolimus-Eluting Stent (Cypher)(Coronary revascularization, PCI-6 (IHD) OJ24,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Ci
- Differential Impact of PercuSurge on Salvage between Successfully Reperfused LAD- and RCA-Related Acute Myocardial Infarction Detected with TL/BMIPP Dual SPECT(Nuclear Cardiology 3 (I), The 69th Annual Scientific Meeting of the Japanese Circulation Societ
- OJ-480 Early Elevation of Serum lnterleukin-6 and High Sensitive CRP Predicts LV Remodeling in Reperfused Myocardial Infarction(Old Myocardial Infarction/Remodeling 1 (IHD) : OJ59)(Oral Presentation (Japanese))
- PE-007 Angiographic Target Lesion Revascularization within 1 Year after Emergent Stenting with Sirolimus-Eluting Stent for Acute Myocardial Infarction(Acute myocardial infarction, clinical (diagnosis/treatment)-4, The 71st Annual Scientific Meeting of the
- OJ-143 Differential Predictors for Binary Restenosis between Bare Metal Stents and Sirolimus-Eluting Stent (Cypher)(Coronary revascularization, PCI-6 (IHD) OJ24,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Ci
- Differential Impact of PercuSurge on Salvage between Successfully Reperfused LAD- and RCA-Related Acute Myocardial Infarction Detected with TL/BMIPP Dual SPECT(Nuclear Cardiology 3 (I), The 69th Annual Scientific Meeting of the Japanese Circulation Societ
- SNPs in the promoter region of the osteopontin gene as a marker predicting the efficacy of interferon-based therapies in patients with chronic hepatitis C
- PJ-387 Angiographic outcome after Primary Stenting to ST-Segment Elevation Acute Myocardial Infarction with Sirolimus- versus Paclitaxel-Eluting Stents(PJ065,ACS/AMI (Clinical/Treatment) 3 (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting
- PE-373 Early Definite Stent Thrombosis of Drugs-Eluting Stents under the First Chosen Thienopyridine Antiplatelet (Ticlopidine versus Clopidogrel) : A Retrospective non-Randomized Study(PE063,Coronary Revascularization, PCI (DES) 5 (IHD),Poster Session (E
- PE-138 Impact of Paclitaxel-Eluting Stent on Predictors of Target Lesion Revascularization of Sirolimus-Eluting Stent : Retrospective Estimation in 2678 Angiographic Followed-up Lesions(PE023,Coronary Revascularization, PCI (DES) 3 (IHD),Poster Session (E
- Molecular Mechanisms of Cholesteryl Ester Transfer Protein Deficiency in Japanese
- Effect of steam explosion pretreatment on treatment with Pleurotus ostreatus for the enzymatic hydrolysis of rice straw(ENVIRONMENTAL BIOTECHNOLOGY)
- PJ-404 PKC signaling pathway is involved in negative inotropic effect and decrease in Ca^ sensitivity during α_1-adrenoceptor stimulation in mouse myocardium(Cardiac Function, Basic/Clinical 2 (M) : PJ68)(Poster Session (Japanese))
- Production of Bifidogenic Growth Stimulator by Co-cultivation of Propionibacterium shermanii and Lactobacillus Strain Using Lactose as a Carbon Source
- Production of Extracellular Bifidogenic Growth Stimulator(BGS) from Propionibacterium shermanii Using a Bioreactor System with a Microfiltration Module and an On-line Controller for Lactic Acid Concentration(BIOCHEMICAL ENGINEERING)
- Production of Extracellular Bifidogenic Growth Stimulator by Anaerobic and Aerobic Cultivations of Several Propionibacterial Strains(BIOCHEMICAL ENGINEERING)
- PE-046 Secondary Cardiac Events in 1118 Patients with Old Myocardial Infarction Revascularized by Sirolimus Eluting Stent and Bare Metal Stents(PE008,Coronary Revascularization, PCI (DES) 1 (IHD),Poster Session (English),The 73rd Annual Scientific Meeting
- PJ-580 Impact of Long-term Continuous Nitrates on Secondary Cardiac Events in Revascularized Old Myocardial Infarction(Acute myocardial infarction, clinical(diagnosis/treatment)(11)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the J
- OE-248 Early Definite Stent Thrombosis after Successful Stenting with Bare-Metal, Sirolimus- and Paclitaxel-Eluting Stents : A High-Volume Single Center Study(Coronary revascularization, PCI(02)(IHD),Oral Presentation(English),The 72nd Annual Scientific M
- PJ-705 Usefulness of Inferior Vena Cava Filter for Prevention of Pulmonary Embolism in Patients with Deep Vein Thrombosis(Pulmonary circulation-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-052 Holter Parameters for Optimal Ventricular Rate Control in Patients with Chronic Atrial Fibrillation(OJ09,ECG/Body Surface Potential Mapping/Holter (A),Oral Presentation (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Socie
- Significantly lower incidence of early definite stent thrombosis of drug-eluting stents after unrestricted use in Japan using ticlopidine compared to western countries using clopidogrel : A retrospective comparison with western mega-studies
- OE-209 Selective coronary arteriogenesis induced by combined administration of bone marrow derived mononuclear cells and ATRA into ischemic myocardium(Angiogenesis 1 (M) : OE26)(Oral Presentation (English))
- Continuous Culture of RPMI 8226 Human Cells
- PATHOGENESIS OF CARDIAC INSUFFICIENCY : PROPORTIONAL CHANGES OF CARDIAC MYOSIN ISOENZYMES IN PATHOLOGICAL : Heart Failure : 46th Annual Scientific Meeting, Japanese Circulation Society
- PJ-296 Atrial Septal Pacing Shows Better Outcome than Atrial Appendage Pacing for Long-Term in Patients with Bradycardia-Tachycardia Syndrome(Arrhythmia, therapy-20, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- 20) THE INFLUENCE OF LONG TERM PRESSURE REGRESSION ON THE VENTRICULAR ISOMYOSIN OF SHR
- Saccharification of Cellulose by Combined Hydrolysis with Acid and Enzyme : Studies on the Re-utilization of Cellulosic Resources (IV).
- Cellulase Productivity of Eupenicillium javanicum : Studies on the Re-utilization of Cellulosic Resources (V).
- Polymorphism of the 3'-Untranslated Region of Interleukin-12 p40 Gene is not Associated With the Presence or Severity of Coronary Artery Disease
- Production of Superoxide Dismutase from Streptococcus lactis Using a Bioreactor with a Microfiltration Module(Microbiology & Fermentation Industry)
- Functional impairment of two novel mutations detected in lipoprotein-associated phospholipase A2 (Lp-PLA2) deficiency patients
- Genetic Analysis of Dilated Cardiomyopathy : HLA and immunoglobulin genes may confer susceptibility : MOLECULAR ANALYSIS OF THE PATHOPHYSIOLOGY OF CARDIOMYPATHY
- -43-CLINICAL CHARACTERISTICS OF ACUTE MYOCARDIAL INFARCTION IN PATIENTS WITH DIABETES MELLITUS : WITH RESPECT TO THE INCIDENCE OF POWER FAILURE
- Continuous Lactic Acid Production from Raw Starch in a Fermentation System Using a Reversibly Soluble-autoprecipitating Amylase and Immobilized Cells of Lactobacillus casei(Microbiology & Fermentation Industry)
- Differential Impact of Smoking on Target Lesion Revascularization after Balloon Angioplasty and Stenting to Ischemic Heart Diseases
- -135-ELECTROCARDIOGRAPHIC AND HISTOPATHOLOGICAL ABNORMALITIES IN CARDIOMYOPATHIC SYRIAN HAMSTERS : Cardiomyopathy : FREE COMMUNICATIONS(I) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- FE-P6 Growth-inhibitory activity of antimicrobial peptides from rice against oral pathogenic bacteria and clarification of their action mechanism(Section IX Food Engineering)
- Renal Insufficiency Predicts Cardiac Event in Revascularized Old Myocardial Infarction during Long-Term Nitrates(Old Myocardial Infarction/Remodeling 3 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- The Effect of Angiotensin Receptor Antagonist and Aldosterone Receptor Antagonist against Cardiac Hypertrophy in Renovascular Hypertensive Rat
- PJ-555 Which Statins have Good Effects in Left Ventricular Remodeling?(Old myocardial Infarction/Remodeling 2 (IHD) : PJ93)(Poster Session (Japanese))
- Treatment of Nonylphenol with Laccase in a Rotating Reactor(ENVIRONMENTAL BIOTECHNOLOGY)
- Enzymatic Oxidative Polymerization of 4-Chloroguaiacol by Laccase
- Facilitation of Rotablator-Stenting by Measuring Angiographic Lesion Length With the Navicath (type-MUTO), a New Measuring Microcatheter
- 0988 AN EFFICACIOUS DRUG-CA ANTAGONIST IN THE CURE OF INFLAMMATORY HEART DISEASE
- PJ-586 Statin Treatment After Myocardial Infarction Reduced Mortality Rate, Improved Cardiac Function And Suppressed Myocardial Fibrosis via Reduced NO Production.(Cardiovascular Pharmacology, Basic/Clinical 5 (H) : PJ98)(Poster Session (Japanese))
- Spironolactone decreased mortality rate and myocardial fibrosis, and improved cardiac function after myocardial infarction
- EFFECT OF PILSICAINIDE HCL(SUN1165),A NOVEL CLASS Ic ANTIARRHYTHMIC AGENT ON CARDIAC FUNCTION AND REPERFUSION ARRHYTHMIAS
- 19) THE INFLUENCE OF INSULIN ON THE CARDIAC DYSFUNCTION IN DIABETIC RAT
- PE-186 How Can We Discriminate the Early Transient Appearance of Atrial Fibrillation from the True Recurrence after Pulmonary Vein Isolation?(Arrhythmia, therapy-10, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PE-121 Reduction of Pulmonary Vein Diameter after Successful Pulmonary Vein Isolation Procedure in Patients with Atrial Fibrillation(Arrhythmia, therapy-09, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PE-120 ATP-induced Transient Reconnection of Pulmonary Veinoccurs More Frequently in Patients with Paroxysmal AF than Persistent AF(Arrhythmia, therapy-09, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-111 Should Cavotricuspid Isthmus Aablation be Performed for All Patients Undergoing Pulmonary Vein Isolation for Atrial Fibrillation?(Arrhythmia, therapy-07, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- OE-219 AF-recurrence after Pulmonary Vein Isolation was Equally Reduced in Paroxysmal and Persistent AF Patients by Eliminating Transient Venous Reconnection(Arrhythmia, therapy-03, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- OE-192 Bi-atrial Volume Reduction through Pulmonary Vein Isolation in Patients with Atrial Fbrillation(Arrhythmia, therapy-02, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- FRS-017 Prevalence and Electrophysiological Characteristics of the Common Inferior Pulmonary Veins in Patients with Atrial Fibrillation(Arrhythmia (clinical) ; Ablation of Atrial Fibrillation, The 71st Annual Scientific Meeting of the Japanese Circulation
- Left Coronary Artery-Left Ventricle Fistula With Right Coronary Artery Spasm
- Cross-Bridge-Dependent Change of the Ca^ Sensitivity During Relaxation in Aequorin-Injected Tetanized Ferret Papillary Muscles
- Cross-Bridge-Dependent Change in Ca^ Sensitivity is Involved in the Negative Inotropic Effect of Nifedipine in Aequorin-Injected Ferret Ventricular Muscles
- Cross-Bridge-Dependent Change of Ca^ Affinity of Troponin C during Relaxation Studied in Aequorin-Injected Tetanized Ferret Papillary Muscles(Cardiac Function, Basic/Clinical 1 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Societ
- OE-198 Properties of The Decay Time of the Ca^ Transient during Isotonic Contraction in Aequorin-injected Ferret Papillary Muscles(Cardiac Function, Basic/Clinical 1 (M) : OE24)(Oral Presentation (English))
- Modulation of L-Type Ca^ Channel Influences the Ca^ Affinity of Troponin-C through the Cross-Bridge Formation in Ferret Ventricular Muscles
- Shortening-Dependent Change of the Decay Time of the Ca^ Transient in Ferret Ventricular Muscles
- Estimation of the change in Ca^ affinity of troponin-C in tetanised ferret ventricular muscles
- Sphingosine 1-phosphate Induces Membrane Ruffling and Increases Motility of HUVEC via Vascular Endothelial Growth Factor Receptor and Crkll
- MUTATION OF MITOCHONDRIAL DNA IN HUMAN AUTOPSIED MYOCARDIUM
- DETERIORATION OF ENDURABLE CAPACITY UNDER PACING OVERLOAD OVERLOAD IN HYPOTHYROLD RAT HEARTS
- THE CORRELATION BETWEEN CARDIAC MYOSIN V_3 CONTENT AND HIGH FREQUENT PACING OVERLOAD INTLERANCE IN DIABETIC RATS
- Impaired longituginal systolic and distolic function in hypertrophic cardiomyopathy
- -0937- THE EFFECT OF HYPOXIA ON Na^+/Ca^+ EXCHANGE IN ISOLATED PERFUSED RAT HEART(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY)
- A POSSIBLE ROLE OF ATP SENSITIVE POTASSIUM CHANNEL ON CARDIAC FUNCTION DURING ISCHEMIA AND REPERFUSION IN ISOLATED PERFUSED RAT HEART
- Aldosterone Augments Angiotensin Converting Enzyme (ACE) Gene Expression Possibly through Nongenomic Glucocorticoid Receptor in Cultured Cardiac Fibroblasts (Heart Failure, Basic 7 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Societ
- EFFECT OF PILSICAINIDE HCL, A CLASS I c ANTI-ARRHYTHMIC AGENT, ON INTRACELLULAR Na^+, pH AND REPERFUSION ARRHYTHMIAS.
- P300 ANALYSIS OF CELL CYCLE-ASSOCIATED GENES AND PROTEINS IN PRESSURE-OVERLOAD CARDLAC HYPERTROPHY
- Myocardial DNA synthesis induced by pressure overload.
- ISOLATION AND PURIFICATION OF CARDIAC GROWTH FACTOR
- THE STUDY ON INTIAL RATE OF SARCOLEMMAL Na^+-Ca^ EXCHANGE IN SHR AND ALLOXAN DIABETES : Cardiac Metabolism (II) : V : 48 Annual Scientific Meeting, Japanese Circulation Society
- CALCIUM BINDING AND Na-Ca EXCHANGE IN CARDIAC SARCOLEMMA IN EXPERIMENTAL HYPERTENSION : Myocardial metabolism . Biochemistry : 46th Annual Scientific Meeting, Japanese Circulation Society
- STUDY ON THE Na-K ATPase ACTIVITY AND Ca BINDING OF MYOCARDIAL SARCOLEMMA OF SPONTANEOUS HYPERTENSIVE RATS : Myocardial metabolism Biochemistry : FREE COMMUNICATIONS (Abstract) : 45 Annual Scientific Meeting, Japanese Circulation Society
- Biochemical Study on the Mucosubstance in Diabetic Vascular Lesion
- EFFECTS OF HIGH-AND LOW-DENSITY LIPOPROTEINS ON HEMODYNAMICS IN ISOLATED PERFUSED RAT HEART
- Acid Base Changes in Ischemic Myocardium and Intervention with Hypothermia or Bicarbonate : SYMPOSIUM ON PATHOPHYSIOLOGY IN THE EARLY STAGE OF ACUTE MYOCARDIAL INFARCTION AND ITS TREATMENT : 51th Annual Scientific Session of the Japanese Circulation Socie
- Insulin Treatment and Myocardial Function in Isolated, Perfused Heart from Diabetic Rat : SYMPOSIUM ON ARTIFICIAL CONTROL OF CIRCULATION : EXPERIMENTAL RESULTS AND CLINICAL APPLICATIONS
- Segmental Pulmonary Vein Antrum Isolation Using the "Large-Size" Lasso Catheter in Patients With Atrial Fibrillation
- -0914- EFFECTS OF ANOXIA AND REOXYGENATION ON INTRACELLULAR Ca^ KINETICS AND SR Ca^ REUPTAKE(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY)
- CALCIUM UPTAKE AND MITOCHONDRIAL FUNCTION OBSERVED IN SITU IN CARDIOMYOCYTES OF EXPERIMENTAL DIABETIC RATS
- -P201- SUBFRACTION OF RAT'S LEFT VENTRICULAR ISOMYOSIN
- Functional and Metabolic Properties in Hearts from Aged Spontaneously Hypertensive Rats : SYMPOSIUM ON LONG-TERM MYOCARDIAL CHANGES IN HEART DISEASES : 49th Annual Scientific Session of the Japanese Circulation Society
- 11)I. ENZYME ACTIVITY OF THE HUMAN CARDIAC MUSCLE II. MYOGLOBIN CONTENT IN THE HUMAN CARDIAC MUSCLE : THE 7th CONFERENCE ON CARDIOMYOPATHY
- THE CONTRACTILE PROTEIN OF HUMAN HEART: CHARACTERIZATION OF MYOSIN HEAVY CHAIN IN HYPERTROPHIED FAILING HUMAN HEART : Myocardial Metabolism : IV Auditorium : PROCEEDINGS OF THE 44th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Altered Myocardial Contractility and Energetics in Hypertrophied Myocardium : 53th Annual Scientific Session of the Japanese Circulation Society
- 5)THE INFLUENCE OF PRESSURE AND METABOLIC LOADS ON THE CARDIAC CONTRACTILE PROTEIN AND FUNCTION : THE 8th CONFERENCE ON CARIDIOMYOPATHY
- Possible roles of Na^+/H^+and CI^-/HCO^-_3 exchangers in the development of Ischemia-reperfusion induced arrhythmias
- EFFECT OF ISCHEMIA ON MYOCARDIAL LIPOPROTEIN LIPASE ACTIVITY IN ISOLATED, PERFUSED RAT HEART : Cardiac Metabolism (I) : IV : 48 Annual Scientific Meeting, Japanese Circulation Society
- Resection of hepatocellular carcinoma with tumor thrombus of the portal vein after neoadjuvant regional chemotherapy
- MYOCARDIAL PROTECTIVE EFFECTS OF INTRINSIC STORAGE IN DIABETIC HEART