Scopolamine Yield in Cultured Roots of Duboisia myoporoides Improved by a Novel Two-stage Culture Method

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概要

• 論文の詳細を見る

• Localization analysis of scopolamine and hyoscyamine 6β-hydroxylase (H6H ; EC 1.14.11.11) contents in Duboisia root cultures showed that scopolamine biosynthesis was accompanied by root elongation. A new two-stage culture method in which the first stage promotes lateral root induction and the second stage enhances root elongation therefore was devised to obtain high scopolamine production. Consequent development of the most suitable media for each stage of culture increased scopolamine productivity 1.8 times that obtained with a one-stage culture. A total of 2500 mg dm^<-3> of scopolamine was produced when this two-stage culture was combined with our high-density culture method.

• 社団法人日本農芸化学会の論文
• 1994-10-23

著者

• Yamada Y

  The Department Of Mechanical Engineering And Intelligent Systems University Of Electro-communication

• Hara Yukihiko

  Food Research Institute Mitsui Norin Co. Ltd.

• Yamada Yukio

  Fine Chemicals Research Laboratories Kaneka Corporation

• Yamada Yukio

  Mechanical Engineering Laboratory Material Science And Bioengineering Department Aist

• Hara Y

  Hiroshima Univ. Higashi-hiroshima Jpn

• Yamada Y

  Fac. Of Education Utsunomiya Univ.

• YAMADA YASUYUKI

  Faculty of Agriculture, Kyoto University

• Yukimune Yukihito

  Bioscience Laboratory, Mitsui Petrochemical Industries, Ltd.

• Hara Yasuhiro

  Bioscience Laboratory, Mitsui Petrochemical Industries, Ltd.

• Tabata Homare

  Bioscience Laboratory, Mitsui Petrochemical Industries, Ltd.

• Tabata H

  Bioscience Laboratory Mitsui Petrochemical Industries Ltd.

• Yukimune Yukihito

  Bioscience Laboratory Mitsui Petrochemical Industries Ltd.

• Yamada Yasuyuki

  Faculty Of Agriculture Kyoto University

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