Strain-Dependent Differences in Locomotor Activity after Local Brain Irradiation with 30 GyE of Carbon Ions

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概要

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• This study investigated strain differences in brain damage among male A/J, C57BL/6JNrs and C3H/HeNrs mice after local brain irradiation. Whole brains were irradiated with a single dose of 30 GyE carbon ion beams and then locomotor activity was determined as body heat of each animal. The daily locomotor activities of untreated mice differed among strains. Non-irradiated C57BL/6JNrs mice were more active than A/J mice. This variance became more obvious immediately after irradiation, when the activity of A/J and C3H/HeNrs mice diminished, whereas that of C57BL/6JNrs mice increased at the beginning of the active phase and remained elevated for three days after irradiation. The altered activities of all three strains of irradiated mice gradually recovered to normal within three to four days.

• 社団法人　日本実験動物学会の論文
• 2005-10-01

著者

• ANDO Koichi

  NIRS

• IMAI Takashi

  Frontier Res. Ctr., NIRS

• Imai Takashi

  Radgenomics Research Group National Institute Of Radiological Sciences

• Imai Takashi

  放射線医学総合研究所フロンティア研究センター 放射線感受性遺伝子プロジェクト

• Ando Koichi

  Heavy-ion Radiobiology Research Group National Institute Of Radiological Sciences

• Imai Takashi

  University Of Tokyo

• Imai Takashi

  National Inst. Radiological Sci. Chiba Jpn

• TAKAI Nobuhiko

  Heavy-ion Radiobio. Res. Grp., Natl Inst. Radiol. Sci.

• IWAKAWA Mayumi

  Frontier Research Center

• GOTO Miyako

  Frontier Research Center

• NODA Shuhei

  Frontier Research Center

• Ando Koichi

  Heavy-ion Radiobiology Res. Group National Inst. Of Radiological Sciences

• Izumi Takashi

  Dept. Of Biochem. Gunma Univ. Graduate Sch. Med.

• ANDO Koichi

  Particle Therapy Radiation Biology Group, National Institute of Radiation Sciences

• ISHIKAWA Takahiro

  Natl Inst Radiol Sci

• Imai Takashi

  Dept. Of Biochem. Gunma Univ. Graduate Sch. Med.

• Imai T

  Rf Heating Laboratory Naka Fusion Research Establishment Japan Atomic Energy Research Institute

• Noda Syuhei

  Radgenomics Project Frontier Research Center National Institute Of Radiological Sciences

• Noda Shuhei

  Radgenomics Project Frontier Research Center National Institute Of Radiological Sciences

• Iwakawa Mayumi

  Radgenomics Research Group National Institute Of Radiological Sciences

• Takai Nobuhiko

  Heavy-ion Radiobiology Research Group National Institute Of Radiological Institute

• ANDO Koichi

  Laboratory of Heavy-ion Radiobiology for Therapy, National Institute of Radiological Science

• Goto Miyako

  Frontier Research Center National Institute Of Radiological Sciences

• Ando Koichi

  Laboratory Of Heavy-ion Radiobiology For Therapy National Institute Of Radiological Science

• Ando Koichi

  Heavy-ion Radio. Res. Nirs

• Ando Koichi

  Clinical Radiation Biology And International Space Radiation Laboratory National Institute Of Radiol

• Ando Koichi

  Heavy-ion Radiobiology Research Group National Institute Of Radiological Institute

• Imai Takashi

  Frontier Res. Ctr. Nirs

• Ando Koichi

  Dept. Of Radiology Kyoto Univ. : National Institute Of Radiological Sciences.

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