Biological Gain of Carbon-ion Radiotherapy for the Early Response of Tumor Growth Delay and against Early Response of Skin Reaction in Mice
スポンサーリンク
概要
- 論文の詳細を見る
The biological effectiveness of carbon ions relative to γ rays (RBE) was compared between the tumor growth delay and an early skin reaction of syngeneic mice. The RBE was larger for a tumor than skin when irradiated with large doses of high-LET (linear energy transfer) carbon ions. The intra-track damage (α term of a linear quadratic model) of a tumor and skin increased equally with an increase of the LET, while the inter-track damage (β term) of skin alone increased with the LET. These data provide evidence that high-LET radiotherapy could achieve therapeutic gain by minimizing the difference in response to fractionated irradiation between the tumor and normal tissue.
- 日本放射線影響学会の論文
- 2005-03-25
著者
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安藤 興一
放医研
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Suzuki Keiji
Course Of Life Sciences And Radiation Research Graduate School Of Biomedical Sciences Nagasaki Unive
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Suzuki Keiji
大阪府立大学先端科学イノベーションセンター 放射線生命科学
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FURUSAWA Yoshiya
Heavy-ion Radiobiology Research Group, Research Center for Charged Particle Therapy, National Instit
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安藤 興一
学振科技特
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安藤 興一
Natl. Instit. Rad. Sci. Med.
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FURUSAWA Yoshiya
National Institute of Radiological Sciences
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FUTAMI Yasuyuki
Shizuoka Cancer Center
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Futami Yasuyuki
茨城県立医療大学 放射線技術科学科
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Futami Yasuyuki
The Institute Of Physics University Of Tsukuba
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Futami Yasuyuki
Dvisin Of Accelerator Physics And Engineering National Institite Of Radiological Sciences Chiba Japa
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Ando Koichi
Heavy-ion Radiobiology Research Group National Institute Of Radiological Sciences
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笹井 啓資
新潟大学医学部放射線医学講座
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小池 幸子
北里大学 獣医学部
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TAKAI Nobuhiko
Heavy-ion Radiobio. Res. Grp., Natl Inst. Radiol. Sci.
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Sasai Keisuke
Heavy-ion Radiobiology Research Group National Institute Of Radiological Sciences
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UZAWA Akiko
Heavy-Ion Radiobiology Research Group, Research Center for Charged Particle Therapy, National Instit
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KOIKE Sachiko
Heavy-Ion Radiobiology Research Group, Research Center for Charged Particle Therapy, National Instit
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Ando K
Division Of Health Sciences Graduate School Of Medicine Osaka University
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Kodama S
Radiation Biology Laboratory Radiation Research Center Frontier Science Innovation Center Organizati
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Ando Koichi
Heavy-ion Radiobiology Res. Group National Inst. Of Radiological Sciences
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Kodama Seiji
Division Of Radiation Biology And Health Science Research Center For Radiation And Radioisotopes Res
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Shibuya Keiko
Department Of Radiation Oncology And Image-applied Therapy Kyoto University Hospital
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Koike Sachiko
Heavy-ion Radiobiology Res. Group National Inst. Of Radiological Sciences
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Sasai Keisuke
京都大学 放射腺腫瘍学･画像応用療学
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Takai Nobuhiko
Heavy-ion Radiobiology Research Group National Institute Of Radiological Sciences
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Uzawa Akiko
Heavy-ion Radiobiology Research Group Research Center For Charged Particle Therapy National Institut
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Aoki M
Heavy-ion Radiobiology Research Group National Institute Of Radiological Sciences
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AOKI Mizuho
Heavy-Ion Radiobiology Research Group, National Institute of Radiological Sciences
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FUKAWA Takeshi
Heavy-Ion Radiobiology Research Group, National Institute of Radiological Sciences
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MIYATO Yasuyuki
Heavy-Ion Radiobiology Research Group, National Institute of Radiological Sciences
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KOIKE Sachiko
National Inst. of Radiol. Sci
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Ando Soichiro
National Institute Of Radiological Sciences
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Ando Koichi
Department Of Technical Support And Development Natl. Inst. Radiol. Sci.
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Ando Koichi
Space And Particle Radiation Science Research Group National Institute Of Radiological Sciences
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Koike Sachiko
Research Center For Charged Particle Therapy Natl. Inst. Radiol. Sci.
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Ando Koichi
Division Of Health Sciences Graduate School Of Medicine Osaka University
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Fukawa Takeshi
Heavy-ion Radiobiology Research Group National Institute Of Radiological Sciences
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Uzawa Akiko
京都大学原子炉実験所附属粒子線腫瘍学研究センター
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Sasai Keisuke
Department Of Radilogy And Nuclear Medicine Faculty Of Medicine Kyoto University
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Furusawa Y
Research Center For Charged Particle Therapy National Institute Of Radiological Sciences
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Furusawa Yoshiya
高エネルギー加速器研究機構物質構造科学研究所
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Fukawa Takeshi
放射線医学総合研究所
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Kasai Soko
Department Of Medicinal Chemistry Center For Frontier Research In Medicinal Science 21st Century Coe
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Kasai Soko
Department Of Biological Science And Technology Faculty Of Engineering University Of Tokushima
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Aoki Mizuho
Heavy-ion Radiobiol. Res. Gr. Natl. Inst. Radiol. Sci.
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Koike Sachiko
Heavy-ion Radiobiology Research Group Research Center For Charged Particle Therapy National Institut
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Takai Nobuhiko
Department Of Molecular And Cellular Pharmacology Nagoya City University
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Miyato Yasuyuki
Heavy-ion Radiobiology Research Group National Institute Of Radiological Sciences
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Furusawa Yoshiya
Heavy-ion Radiobiology Res. Group National Inst. Of Radiological Sciences
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Ando Koichi
Heavy-ion Radio. Res. Nirs
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Ando Koichi
International Space Radiation Laboratory National Institute Of Radiological Sciences
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Furusawa Yoshiya
Div. Of Accelerator Res. Natl. Inst. Of Radiol. Sci.
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Furusawa Yoshiya
Heavy-ion Radiobiol. Res. Gr. Res. Center Charged Particle Therapy Nirs.
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Fukawa Takeshi
慶応義塾大学
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