Protein Crystal Processing Using a Deep-UV Laser
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概要
- 論文の詳細を見る
We propose a new protein crystal processing technique, pulsed UV laser soft ablation (PULSA). This is the first report on the successful processing of protein crystals using an optical light source without causing significant damage to the crystal. Photoablation without thermal degradation of the protein crystal structure was achieved using deep-UV laser pulses at a wavelength of 193 nm. The PULSA technique did not affect the quality of the crystals used for X-ray data collection. Moreover, complicated and precise processing of protein crystals, which is difficult using conventional mechanical tools, has been achieved using PULSA. This technique will undoubtedly be a powerful tool for processing protein crystals.
- Japan Society of Applied Physicsの論文
- 2004-01-15
著者
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Takano Kazufumi
SOSHO Project (Crystal Design Project), Osaka University
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Matsumura Hiroyoshi
SOSHO Project (Crystal Design Project), Osaka University
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Inoue Tsuyoshi
SOSHO Project (Crystal Design Project), Osaka University
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Kitano Hiroshi
Core Technology Center Nikon Corporation
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Owa Soichi
Core Technology Center Nikon Corporation
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Mori Yusuke
Department Of Applied Chemistry School Of Science And Engineering Waseda University
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Adachi Hiroaki
Department Of Biological Science Faculty Of Science Hiroshima University
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Sasaki Takatomo
Department Of Electrical Electronic And Information Engineering Osaka University
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Murakami Atsutoshi
Department of Electrical Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan
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Adachi Hiroaki
Department of Electrical Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan
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Inoue Tsuyoshi
SOSHO Project (Crystal Design Project), Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan
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Owa Soichi
Core Technology Center, Nikon Corporation, 1-6-3 Nishi-Ohi, Shinagawa-ku, Tokyo 140-8601, Japan
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