Enhancement of the Activity of a Lactobacilli-Aggregating Peptide by Freezing Treatment
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概要
- 論文の詳細を見る
The effects of freezing treatments on the activity of the lactobacilli-aggregating peptide QRCVNLQA were studied. The aggregation activity of the peptide solution was enhanced by rapid deep freezing in liquid nitrogen followed by storage for at least 1 d below -10°C. The treated peptide strongly induced the aggregation of suspended cells of Lactobacillus rhamnosus GG to provide a clear supernatant after 1.5 h. The peptide was activated by oxidation of thiol groups, probably through dimerization of the peptide molecules to form disulfide bonds. Addition of the freeze-oxidized peptide to a suspension of lactobacilli promoted the adhesion of the lactobacilli to a monolayer of Caco-2 intestinal epithelial cells.
- Society of Chemical Engineers, Japanの論文
著者
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Kato Ryuji
Department Of Biotechnology Graduate School Of Engineering Nagoya University
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Nakagawa Kyuya
Department Of Mechanical Engineering University Of Hyogo
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Honda Hiroyuki
Department Of Anesthesia Niigata City General Hospital
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Okochi Mina
Department Of Biotechnology Graduate School Of Engineering Nagoya University
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Sugita Tomoya
Department Of Biotechnology Graduate School Of Engineering Nagoya University
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Okochi Mina
Department of Biotechnology, Graduate School of Engineering, Nagoya University
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ASAI Yuji
Department of Biotechnology, Graduate School of Engineering, Nagoya University
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Kato Ryuji
Department of Biotechnology, Graduate School of Engineering, Nagoya University
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Nakagawa Kyuya
Department of Mechanical and System Engineering, University of Hyogo
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