微生物による<I>n</I>-アルカンおよびメタノールの変換

概要

論文の詳細を見る
Various specific features have been observed with respect to cytological and metabolic properties of microorganisms which can utilize alkanes or methanol as sole carbon and energy source. Based on the fact, a variety of useful cellular components and metabolites, such as amino acids, organic acids, sugar alcohols, polysaccharides, nucleotides, vitamins and coenzymes, antibiotics, enzymes, biomass etc., can be produced by microbial processes utilizing alkanes or methanol as substrate. These products are classified into three groups : (1) The group 1 involves compounds which can be also produced by conventional fermentation of carbohydrates ; (2) The group 2 contains products whose formation from non-sugar substrates is markedly favoured by physiological and metabolic features of microorganisms utilizing such unconventional carbon sources ; (3) The group 3 consists of products to be formed directly from non-sugar substrates. Although these compounds are rarely manufactured from non-sugar substrates on industrial scale at present, the production of compounds belonging to Groups 2 and 3 is not only of academic interest but also of industrial importance. This review summarizes the microbial utilization of alkanes and methanol from fundamental and practical viewpoints.
社団法人有機合成化学協会の論文