Effects of methamphetamine on dopamine cells in the substantia nigra pars compacta and the ventral tegmental area.
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概要
- 論文の詳細を見る
The ability of methamphetamine to inhibit the firing rate of dopamine cells in the substantia nigra pars compacta (SNC) and the ventral tegmental area (VTA) was studied. Methamphetamine reduced the firing rates of the dopamine cells in a dose-dependent manner in the SNC and the VTA. The doses of methamphetamine required to produce a 50% inhibition of firing rate in the SNC and the VTA were 0.37 mg/kg and 0.28 mg/kg, respectively.
- 公益社団法人 日本薬理学会の論文
著者
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Kameyama Tsutomu
Department Of Biological Chemistry Faculty Of Pharmaceutical Sciences Nagoya City University
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KAMATA Katsuo
Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Meijo University
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