Effect of Rapessed and Dietary Oils on the Mean Survival Time of Stroke-Prone Spontaneously Hypertensive Rats
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概要
- 論文の詳細を見る
Low-fat conventional diets supplemented with 5 or 10% vegetable oils were fed to stroke-prone spontaneously hypertensive rats (SHR-SP9) from weaning and the mean survival times were determined. A 1% aqueous sodium chloride solution was used as drinking water throughout the experiments. In four separate experiments, the rapeseed oil group showed a significantly shorter mean survival time. The relative mean survival times were 50-59% (rapeseed oil group), 78-106% (soybean oil group) and 86% (microbial oil group) as compared with the group fed perilla oil (100%). The group which received 4-fold diluted rapeseed oil exhibited a significantly shorter survival time as compared with the group receiving soybean oil. Although the feeding experiments were performed under very simple and restricted conditions, these results suggest that the rapeseed oil prepared for human use contains a factor (s) which is toxic to SHR-SP rats.
- 社団法人日本薬学会の論文
- 1996-04-15
著者
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OKUYAMA Harumi
Open Research Center for Lipid Nutrition, Kinjo Gakuin University College of Pharmacy
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Okuyama H
Nagoya City Univ. Nagoya Jpn
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Okuyama Harumi
Department Of Biological Chemistry Faculty Of Pharmaceutical Sciences Nagoya City University
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Huang Min-zhao
Department Of Biological Chemistry Faculty Of Pharmaceutical Sciences Nagoya City University
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HUANG Min-Zhao
Faculty of Pharmaceutical Sciences Nagoya City University
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NAITO Yukio
Faculty of Pharmaceutical Sciences Nagoya City University
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WATANABE Shiro
Faculty of Pharmaceutical Sciences Nagoya City University
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KOBAYASHI Tetsuyuki
Faculty of Pharmaceutical Sciences Nagoya City University
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KANAI Hideki
Faculty of Medicine Nagoya City University
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NAGAI Hajime
Faculty of Medicine Nagoya City University
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OKUYAMA Harumi
Faculty of Pharmaceutical Sciences Nagoya City University
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NAKASHIMA Yumiko
Graduate School of Pharmaceutical Sciences, Osaka University
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Naito Y
Department Of Biological Chemistry Faculty Of Pharmaceutical Sciences Nagoya City University
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Kameyama Tsutomu
Faculty Of Pharmaceutical Sciences Nagoya City University
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Nakashima Y
Shimonoseki City Central Hospital Department Of Pediatrics
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Kameyama T
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences Meijo University
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Kameyama Tsutomu
Department Of Biological Chemistry Faculty Of Pharmaceutical Sciences Nagoya City University
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Kameyama Tsutomu
Dept. Of Chem. Pharmaco. Meijo Univ.
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Watanabe Shiro
Department of Preventive Nutraceutical Sciences, Graduate School of Pharmaceutical Sciences Nagoya City University
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