Antioxidative Compounds Isolated from Safflower (Carthamus tinctorius L.) Oil Cake
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概要
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Seven antioxidative serotonin derivatives were isolated from safflower (Carthamus tinctorius L.) oil cake. Their structures were established as N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]ferulamide (1), N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-p-coumaramide (2), N, N'-[2,2'-(5,5'-dihydroxy-4,4'-bi-1H-indol-3,3'-yl)diethyl]-di-p-coumaramide (3,) N-[2-[3'-[2-(p-coumaramido)ethyl]-5,5'-dihydroxy-4,4'-bi-1H-indol-3-yl]ethyl]ferulamide (4), and N, N'-[2,2'-(5,5'-dihydroxy-4,4'-bi-1H-indol-3,3'-yl)diethyl]-diferulamide (5), N-[2-[5-(β-D-glucosyloxy)-1H-indol-3-yl]ethyl]-p-coumaramide (6), and N-[2-[5-(β-D-glucosyloxy)-1H-indol-3-yl]ethyl]ferulamide (7). Antioxidative activities of the compounds were measured by the ferric thiocyanate method and the α, α-diphenyl-β-picrylhydrazyl (DPPH) method, and compounds 1-5 were found to have relatively strong antioxidative activity.
- 公益社団法人日本薬学会の論文
- 1997-12-15
著者
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渡辺 敏子
School Of Pharmaceutical Sciences Toho University
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Zhang H
Nagoya City Univ. Nagoya
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永津 明人
名市大院薬
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Zhang Hui
Faculty Of Pharmaceutical Sciences Nagoya City University
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Nagatsu Akito
Faculty Of Pharmaceutical Sciences Nagoya City University
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Watanabe Toshifumi
Pharmaceutical Research Laboratories Ii Pharmaceutical Research Division Takeda Chemical Industries
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OKUYAMA Harumi
Faculty of Pharmaceutical Sciences Nagoya City University
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Watanabe T
Chiba Univ. Chiba Jpn
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WATANABE Toshihiro
Faculty of Pharmaceutical Sciences, Nagoya City University
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Watanabe Toshiko
Faculty Of Pharmaceutical Sciences Chiba University
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Watanabe Toshiko
Graduate School Of Pharmaceutical Sciences Chiba University
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Watanabe Toshihiro
Institute For Drug Discovery Research Yamanouchi Pharmaceutical Co. Ltd.
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Watanabe Toshihiro
Faculty Of Agriculture Hokkaido University
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Zhang Hai
School Of Traditional Chinese Medicine Shenyang Pharmaceutical University
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Sakakibara J
Faculty Of Pharmaceutical Sciences Nagoya City University
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OKUYAMA Harumi
Faculty of Pharmaceutical Sciences, Nagoya City University
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