Pathophysiological Effects of Dietary Essential Fatty Acid Balance on Neural Systems
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概要
- 論文の詳細を見る
Dietary fatty acid balance has been revealed to affect neural functions as well as chronic diseases such as cancer, cerebro- and cardiovascular diseases, and allergic hyper-reactivity. In this review, we focused on the pathophysiological effects of n-6 and n-3 fatty acids on brain functions. Long-term n-3 fatty acid deficiency in the presence of n-6 fatty acids has been shown to affect learning behavior, drug sensitivity and retinal functions. Some membrane enzymes and ion channel functions have been shown in experimental animals to be regulated by membrane fatty acid modifications. We also summarized the effects of these fatty acids in diets on human psychotic aspects and brain diseases. Although biochemical mechanisms remain to be elucidated, investigations on the effect of dietary fatty acids on neural networks may provide an important clue to clarify complex brain functions.
- 社団法人 日本薬理学会の論文
- 1998-05-01
著者
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OKUYAMA Harumi
Faculty of Pharmaceutical Sciences Nagoya City University
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Yoshida Satoshi
Research Centre For Radiation Protection National Institute Of Radiological Sciences
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Yoshida S
Institute Of Industrial Science The University Of Tokyo
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SATO Akira
Faculty of Pharmaceutical Sciences, Nagoya City University
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Sato Akira
Faculty Of Engineering Tohokugakuin University.
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Sato Akira
Faculty Of Pharmaceutical Sciences Nagoya City University
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Yoshida Satoshi
Institute of Industrial Science, The University of Tokyo
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