A Case of Recovery from Canine Destructive Cholangitis in a Miniature Dachshund
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概要
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A 7-year-old Miniature Dachshund presented with severe chronic jaundice and elevated liver enzymes. Destructive cholangitis was diagnosed according to histopathological findings of remarkable ductopenia with inflammatory infiltrates and fibrosis in the portal areas. Supportive therapy with prednisolone, high-dose ursodeoxycholic acid, human placental extract and antibiotics was tried and the patient showed recovery of clinical signs 3 months after diagnosis. Second liver biopsy was performed about 1 year after initial diagnosis and bile duct restoration was confirmed with continuous inflammation around portal areas and inside the lobules. Although we could not determined which treatment was effective in this case, destructive cholangitis in dogs may be able to recover with long-term supportive therapies.
著者
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TSUJIMOTO Hajime
Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The U
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FUJINO Yasuhito
Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The U
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OHNO Koichi
Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The U
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OSUMI Takafumi
Department of Pathobiology, College of Bioresource Sciences, Nihon University
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Uchida Kazuyuki
Department of Veterinary Pathology, Faculty of Agriculture, University of Miyazaki
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KANEMOTO Hideyuki
Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The U
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Fujino Yasuhito
Department Of Veterinary Internal Medicine Graduate School Of Agricultural And Life Sciences The Uni
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NAKASHIMA Ko
Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The U
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KARASAWA Ayako
Omi Animal Hospital
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Osumi Takafumi
Department Of Pathobiology College Of Bioresource Sciences Nihon University
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Ohno Koichi
Department Of Chemical Engineering Faculty Of Engineering Niigata University
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Tsujimoto Hajime
Department Of Internal Medicine And Veterinary Hospital Division Of Veterinary Medicine The Universi
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Uchida Kazuyuki
Department Of Veterinary Pathology Graduated School Of Agricultural And Life Sciences The University
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OHNO Koichi
Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo
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NAKASHIMA Ko
Department of Veterinary Internal Medicine Graduate School of Agricultural and Life Sciences, The University of Tokyo
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KANEMOTO Hideyuki
Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo
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