Immunological Findings in 3 Dogs Clinically Diagnosed with Allergic Rhinitis
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概要
- 論文の詳細を見る
Three dogs clinically diagnosed with allergic rhinitis (AR) were examined for their immunological findings. House dust mites (HDM) such as Dermatophagoides farinae (DF) and D. pteronyssinus (DP) were identified as positive allergens in the 3 dogs with both intradermal skin test and serum antigen-specific IgE test. Lymphocyte blastogenic response of peripheral blood mononuclear cells (PBMCs) under stimulation with DF antigen in dogs with AR was higher than that in 4 healthy control dogs. Expression level of IL-4 mRNA in PBMCs obtained from the 3 AR dogs was higher than that in PBMCs obtained from 4 healthy control dogs before and after stimulation with DF antigen. Expression level of IFN-γ mRNA in PBMCs was not different between the AR and control dogs before and after stimulation with DF antigen. These results suggested that allergic reaction to HDM antigen and TH2-type immune response were associated with the development of AR in 3 dogs examined in this study.
- 社団法人 日本獣医学会の論文
- 2004-01-25
著者
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TSUJIMOTO Hajime
Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The U
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SAKAGUCHI Masahiro
Department of Veterinary Microbiology, School of Veterinary Medicine, Azabu University
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OHNO Koichi
Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The U
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Tsujimoto Hajime
Department Of Veterinary Internal Medicine Graduate School Of Agricultural And Life Sciences The Uni
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Kurata Keigo
Department Of Veterinary Internal Medicine Graduate School Of Agricultural And Life Sciences The Uni
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Ohno Koichi
Department Of Veterinary Internal Medicine Graduate School Of Agricultural And Life Sciences The Uni
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Kurata Keigo
Department Of Immunology National Institute Of Infectious Diseases
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Masuda Kenichi
Animal Allergy Clinical Laboratories Inc.
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Masuda Kenichi
Department Of Veterinary Internal Medicine Graduate School Of Agricultural And Life Sciences The Uni
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Masuda Kenichi
Department Of Orthopaedic Surgery Kansai College Of Oriental Medicine
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MAEDA Sadatoshi
Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The U
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YASUNAGA Sho
Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The U
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Ohno Koichi
Department Of Chemical Engineering Faculty Of Engineering Niigata University
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Yasunaga Sho
Department Of Veterinary Internal Medicine Graduate School Of Agricultural And Life Sciences The Uni
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Tsujimoto Hajime
Department Of Internal Medicine And Veterinary Hospital Division Of Veterinary Medicine The Universi
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Sakaguchi Masahiro
Department Of Anesthesiology Kyoto Prefectural University Of Medicine
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Maeda Sadatoshi
Department Of Veterinary Internal Medicine Graduate School Of Agricultural And Life Sciences The Uni
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Sakaguchi Masahiro
Department Of Immunology National Institute Of Infectious Diseases
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