Membranoproliferative Glomerulonephritis in a Young Cat(Pathology)
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概要
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A 9-montn-old male Japanese domestic cat showed pleural effusion, ascites, azotemia, hypoproteinemia and severe proteinuria. Histopathology of the percutaneous renal biopsy specimen revealed that all glomeruli showed intense mesangial hypercellularity with an increased mesangial matrix and thickening of the capillary walls, resulting in lobular accentuation of the glomerular tufts. Frequent duplication of the capillary walls was also observed. Immunostaining for α-smooth muscle actin distinctly revealed mesangial interposition. Diffuse global and linear deposition of C3 and IgG was observed mostly along the peripheral capillary loops. Electron microscopy confirmed frequent circumferential mesangial interposition and subendothelial dense-deposits in the glomerulus. The glomerular lesion was consistent with human membranoproliferative glomerulonephritis type I, and might be a rare case that developed at young age.
- 社団法人日本獣医学会の論文
- 2008-12-25
著者
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OHNO Koichi
Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The U
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Kamiie Junichi
Laboratory Of Veterinary Pathology School Of Veterinary Medicine Azabu University
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Kamiie Junichi
Laboratory Of Veterinary Pathology Azabu University
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SHIROTA Kinji
Research Institute of Biosciences, Azabu University
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Shirota Kinji
Research Institute Of Biosciences And High-tech Research Center Azabu University
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Shirota Kinji
Research Institute Of Biosciences Azabu University:laboratory Of Veterinary Pathology Azabu Universi
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OGIHARA Kikumi
Laboratory of Environmental Pathology, Azabu University
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ASANO Tomoko
Research Institute of Biosciences, Azabu University
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TSUKAMOTO Atsushi
Department of Veterinary Internal Medicine, The University of Tokyo
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Asano Tomoko
Research Institute Of Biosciences Azabu University
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Ogihara Kikumi
Laboratory Of Environmental Pathology Azabu University
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Tsukamoto Atsushi
Department Of Veterinary Internal Medicine The University Of Tokyo
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Ohno Koichi
Department Of Veterinary Internal Medicine The University Of Tokyo
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Ohno Koichi
Department Of Chemical Engineering Faculty Of Engineering Niigata University
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Ogihara Kikumi
Laboratories Of Environmental Pathology
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