Identification of Cell Surface Antigen Expression in Canine Hepatocellular Carcinoma Cell Lines
スポンサーリンク
概要
- 論文の詳細を見る
The characteristics of surface antigens in canine hepatocellular carcinoma (cHCC) have not been clarified. The objective of this study was to investigate surface antigens, which are considered as stem/progenitor or cancer cell markers, in cHCC cell lines. Expression of various antigens including CD29, CD34, CD44, CD90, CD133 and Dlk-1 was assessed in four cHCC cell lines by flow cytometry. CD44, CD133 and Dlk-1 expression was detectable in all cell lines, and three cell lines expressed CD29. These results indicate that CD29, CD44, CD133 and Dlk-1 have potential as suitable markers in cHCC identification, suggesting that these findings will contribute to the establishment of an early diagnostic tool for the identification of hepatocellular maturation processes.
著者
-
NEO Sakurako
Laboratory of Internal Medicine II, School of Veterinary Medicine, Azabu University
-
Tsuchiya Ryo
Laboratory Of Internal Medicine Ii School Of Veterinary Medicine Azabu University
-
Hisasue Masaharu
Laboratory Of Internal Medicine Ii School Of Veterinary Medicine Azabu University
-
Ogihara Kikumi
Laboratories Of Environmental Pathology
-
SEGAWA Kazuhito
Laboratory of Internal Medicine II, School of Veterinary Medicine, Azabu University, 1–17–71 Fuchinobe, Chuoku, Sagamihara, Kanagawa 252–5201, Japan
-
KAWARAI Shinpei
Department of Veterinary Teaching Hospital, School of Life and Environmental Science, Azabu University, 1–17–71 Fuchinobe, Chuoku, Sagamihara, Kanagawa 252–5201, Japan
-
KAWARAI Shinpei
Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo
-
FUJIMOTO Ayumi
Laboratory of Veterinary Internal Medicine II, School of Veterinary Medicine, Azabu University, 1–17–71 Fuchinobe, Chuoku, Sagamihara, Kanagawa 252–5201, Japan
-
ISHIZUKA Chinatsu
Laboratory of Veterinary Internal Medicine II, School of Veterinary Medicine, Azabu University, 1–17–71 Fuchinobe, Chuoku, Sagamihara, Kanagawa 252–5201, Japan
-
KATO Takashi
Laboratory of Veterinary Internal Medicine II, School of Veterinary Medicine, Azabu University, 1–17–71 Fuchinobe, Chuoku, Sagamihara, Kanagawa 252–5201, Japan
-
FUJIMOTO Ayumi
Laboratory of Internal Medicine II, School of Veterinary Medicine, Azabu University, 1–17–71 Fuchinobe, Chuoku, Sagamihara, Kanagawa 252–5201, Japan
-
NEO Sakurako
Laboratory of Veterinary Internal Medicine II, School of Veterinary Medicine, Azabu University, 1–17–71 Fuchinobe, Chuoku, Sagamihara, Kanagawa 252–5201, Japan
-
KATO Takashi
Laboratory of Internal Medicine II, School of Veterinary Medicine, Azabu University, 1–17–71 Fuchinobe, Chuoku, Sagamihara, Kanagawa 252–5201, Japan
関連論文
- Potential Immunological Adjuvant of K-Type CpG-Oligodeoxynucleotides Enhanced the Cell Proliferation and IL-6 mRNA Transcription in Canine B cells
- Preparation of Positive Control Platelets for Detection of Canine Platelet Surface-Associated IgG, IgM and Complement (C3) by Flow Cytometry
- Bone Marrow Colony-Forming Unit Assay in Cats With Naturally Occurring Myelodysplastic Syndromes
- A Case of Canine Vasotropic and Vasoinvasive Nonepitheliotropic Lymphoma with Unusual Tumor Cells and Extensive Dermal Necrosis(Pathology)
- Membranoproliferative Glomerulonephritis in a Young Cat(Pathology)
- Endometrial Polyps in a Cat
- A Case of Atypical Canine Lymphoma with Oral Mass and Multiple Osteolysis
- Neutropenia Associated with Osteomyelitis due to Hepatozoon canis Infection in a Dog
- Pathological Characterization of Collagenofibrotic Glomerulonephropathy in a Young Dog
- Aggregability and Post-Transfusion Survival of Canine Platelets in Stored Whole Blood
- Retrospective Study of Canine Insulinomas: Eight Cases (2005-2008)
- Cutaneous Clear Cell Adnexal Carcinoma in a Dog: Special Reference to Cytokeratin Expression
- Identification of Bovine Serum Albumin as an IgE-Reactive Beef Component in a Dog with Food Hypersensitivity against Beef
- Establishment of a Lens Epithelial Cell Line from a Canine Mature Cataract
- A Dog with Myelodysplastic Syndrome: Chronic Myelomonocytic Leukemia
- cDNA Sequence and Tissue Distribution of Canine Na-Dependent Neutral Amino Acid Transporter 2 (ASCT 2)
- Membranoproliferative Glomerulonephritis in a Young Cat
- Accumulation of Xenotransplanted Canine Bone Marrow Cells in NOD/SCID/γcnull Mice with Acute Hepatitis Induced by CCl4
- Identification of Cell Surface Antigen Expression in Canine Hepatocellular Carcinoma Cell Lines
- Notch2 Transduction by Feline Leukemia Virus in a Naturally Infected Cat