Congenital Cutaneous Fibropapillomatosis with No Evidence of Papillomavirus Infection in a Piglet
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概要
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Multiple yellowish-white, cauliflower-like mass lesions on the skin of the head and back in a 4-month-old piglet were pathologically examined. These lesions had developed before the weaning period. Histologically, the cutaneous neoplasms were characterized by papillary outgrowth of connective tissue covered by thick epidermis. Hyperplasia of the epidermis was corresponded with proliferation of capillaries, lympho-plasmacytic infiltration, and proliferation of fibroblasts in the dermal stroma. There were no inclusion bodies and significant degeneration in the keratinocytes. Papillomavirus antigen and DNA were not detected in these lesions by immunohistochemistry and polymerase chain reaction, respectively. Accordingly, the fibropapillomatosis of the present case might be hamartomatous rather than infectious.
著者
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Kamiie Junichi
Laboratory Of Veterinary Pathology Azabu University
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Shirota Kinji
Research Institute Of Biosciences And High-tech Research Center Azabu University
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SHIGA Akira
Shiga Swine Clinic
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KOBAYASHI Yoshiyasu
Laboratory of Veterinary Pathology, Department of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080–8555, Japan
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KOBAYASHI Yoshiyasu
Laboratory of Veterinary Pathology, Division of Pathological Science, Department of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine
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NISHIYAMA Shoko
Research Institute of Bioscience, Azabu University
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AKIBA Yumi
Laboratory of Veterinary Pathology, Division of Pathological Science, Department of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine
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