Blood Hyaluronic Acid as a Marker for Canine Cirrhosis
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概要
- 論文の詳細を見る
Blood hyaluronic acid (HA) concentration was measured in dogs with various liver diseases to determine its relationship with histological fibrosis of the liver. The blood HA concentration significantly increased in dogs with chronic liver diseases compared with extrahepatic diseases and control. Furthermore, the median blood HA concentration in dogs with liver cirrhosis (500 μg/l; range, 151-1970 μg/l) was significantly higher than dogs with non-cirrhotic liver diseases (153 μg/l; range, 15-477 μg/l). In histochemical analysis, HA was distributed primarily in the fibrotic area in dogs with chronic liver diseases. As a conclusion, the blood HA concentration was significantly increased in dogs with chronic liver diseases, especially those with cirrhosis. Measurement of the blood HA levels of dogs with suspected liver disease can be a useful diagnostic aid for canine cirrhosis.
- 公益社団法人 日本獣医学会の論文
著者
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KANEMOTO Hideyuki
Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The U
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Fujino Yasuhito
Department Of Veterinary Internal Medicine Graduate School Of Agricultural And Life Sciences The Uni
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Ohno Koichi
Department Of Chemical Engineering Faculty Of Engineering Niigata University
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Tsujimoto Hajime
Department Of Internal Medicine And Veterinary Hospital Division Of Veterinary Medicine The Universi
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Sakai Manabu
Department Of Mathematics And Computer Science Graduate School Of Science And Engineering Kagoshima
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Takahashi Masashi
Department Of Animal And Grassland Research National Agricultural Center For Kyushu Okinawa Region
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SAKAI Manabu
Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University
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NAKASHIMA Ko
Department of Veterinary Internal Medicine Graduate School of Agricultural and Life Sciences, The University of Tokyo
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KANEMOTO Hideyuki
Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo
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