一過性大脳虚血を施したスナネズミ皮質体性感覚野におけるGlutamic acid decarboxylase 67免疫反応性ならびにタンパク質レベルの一過性増加(解剖学)
スポンサーリンク
概要
- 論文の詳細を見る
本研究では,虚血/再還流を施したスナネズミ大脳皮質体性感覚野におけるglutamic acid decarboxylase 67 (GAD67)免疫反応性とタンパク質レベルの変化を検討した.GAD67免疫反応は虚血/再還流後12時間の皮質第IIIならびにV層で有意に増加した.その後,GAD67免疫反応は時間とともに減少し,4日後では偽手術群に類似するようになった.さらに,GAD67タンパク質レベルも一過性虚血12時間後に有意に増加した.これらの結果は,皮質第IIIならびにV層のGAD67免疫反応が一過性虚血による神経損傷に反応して増加することを示す.
- 2008-09-25
著者
-
HWANG In
Department of Anatomy and Cell Biology, College of Veterinary Medicine and BK21 Program for Veterina
-
CHOI Jung
Department of Anatomy and Neurobiology, College of Medicine, Hallym University
-
LI Hua
Department of Anatomy and Neurobiology, College of Medicine, Hallym University
-
YOO Ki-Yeon
Department of Anatomy and Neurobiology, College of Medicine, Hallym University
-
LEE Choong
Department of Anatomy and Cell Biology, College of Veterinary Medicine and BK21 Program for Veterina
-
WON Moo-Ho
Department of Anatomy and Neurobiology, College of Medicine, Hallym University
-
Won Moo
Department Of Anatomy And Neurobiology College Of Medicine Hallym University:institute Of Neurodegen
-
Hwang In-koo
Department Of Anatomy And Cell Biology College Of Veterinary Medicine And Bk21 Program For Veterinar
-
Hwang In
韓国
-
Yoo Ki-yeon
Department Of Anatomy College Of Medicine Hallym University
-
Kim Yo
Department Of Anatomy And Cell Biology College Of Veterinary Medicine And Bk21 Program For Veterinar
-
Hwang In
Department Of Anatomy And Cell Biology College Of Veterinary Medicine And Bk21 Program For Veterinar
-
Kwon Dae
Food Function Res. Div. Korea Food Res. Inst.
-
Lee Choong
Department Of Anatomy And Neurobiology College Of Medicine Hallym University
-
Park Ok
Department Of Anatomy And Neurobiology College Of Medicine Hallym University
-
Lee Choong
Department Of Anatomy And Cell Biology College Of Veterinary Medicine And Bk21 Program For Veterinar
-
Choi Jung
Department Of Anatomy And Neurobiology College Of Medicine Hallym University
-
Li Hua
Hallym Univ. Chuncheon
-
Nam Young
Department Of Anatomy College Of Veterinary Medicine And School Of Agricultural Biotechnology Seoul
-
KWON Dae
Korea Food Research Institute
-
Yoo Ki‐yeon
Hallym Univ. Chuncheon
-
Kim Yeong-in
Department Of Neurology Kangnam St. Mary's Hospital The Catholic University Of Korea
-
Lee Heungshik
Department Of Anatomy College Of Veterinary Medicine And School Of Agricultural Biotechnology Seoul
-
Yoo Ki-yeon
Department Of Anatomy And Cell Biology College Of Veterinary Medicine And Bk21 Program For Veterinar
-
Choi Jung
Department Of Agricultural Biotechnology Seoul National University
-
Won M.H.
Department of Anatomy and Neurobiology, College of Medicine, Hallym University:Institute of Neurodegeneration and Neuroregeneration, Hallym University
-
Hwang In
Department of Anatomy and Cell Biology, College of Veterinary Medicine and BK21 Program for Veterinary Science, Seoul National University
-
WON Moo-Ho
Department of Anatomy and Neurobiology, and Institute of Neurodegeneration and Neuroregeneration, College of Medicine, Hallym University
-
LI Hua
Department of Anatomy and Neurobiology, and Institute of Neurodegeneration and Neuroregeneration, College of Medicine, Hallym University
関連論文
- 成犬ならびに老犬の歯状回と海馬におけるグリア線維酸性蛋白免疫染色性の変化(解剖学)
- 癲癇抵抗性及び感受性スナネズミの海馬における小膠細胞及び星状膠細胞マーカータンパク質の特異的免疫反応性(解剖学)
- 一過性大脳虚血を施したスナネズミ皮質体性感覚野におけるGlutamic acid decarboxylase 67免疫反応性ならびにタンパク質レベルの一過性増加(解剖学)
- 癪癇感受性スナネズミの視床下部室旁核におけるTyrosine hydroxylaseの減少(解剖学)
- スナネズミ十二指腸の筋層間神経叢におけるカルビンジンD-28k陽性ニューロンの年齢に伴う変化(解剖学)
- Gliosis in the Amygdala Following Myocardial Infarction in the Rat
- スナネズミ海馬CA1領域におけるイオン化カルシウム結合アダプター分子1の免疫反応性及びタンパクレベルの年齢に伴う変化(解剖学)
- 種々月齢の特発性高血圧ラット歯状回におけるDoublecortin陽性神経前駆細胞 : SDラットとの比較について(解剖学)
- 成犬と老犬の海馬CA1領域における脂質過酸化反応とCu,Zn-superoxide dismutaseの違い(解剖学)
- Exendin-4 Potentiates Insulinotropic Action Partly via Increasing β-Cell Proliferation and Neogenesis and Decreasing Apoptosis in Association With the Attenuation of Endoplasmic Reticulum Stress in Islets of Diabetic Rats
- Comparison of α-synuclein immunoreactivity and protein levels in ischemic hippocampal CA1 region between adult and aged gerbils and correlation with Cu,Zn-superoxide dismutase
- Anatomy: Effects of electroacupuncture at Zusanli and Baihui on brain-derived neurotrophic factor and cyclic AMP response element-binding protein in the hippocampal dentate gyrus
- Whole Blood and Red Blood Cell Manganese Reflected Signal Intensities of T1-Weighted Magnetic Resonance Images better than Plasma Manganese in Liver Cirrhotics
- Effects of Methimazole on the Onset of Type 2 Diabetes in Leptin Receptor-Deficient Rats(Laboratory Animal Science)
- Ge/GeO_2 Interface Control with High-Pressure Oxidation for Improving Electrical Characteristics
- Effects of Ginkgo biloba Extract on Promotion of Neurogenesis in the Hippocampal Dentate Gyrus in C57BL/6 Mice
- Fluorescent Calix[4]arene-appended Silica Nanotubes as Selective Chemosensor and Adsorbent for Pb^ Ion
- Antimutagenicity and Cytotoxicity of the Constituents from the Aerial Parts of Rumex acetosa(Pharmacognosy)
- Perineural invasion is a prognostic factor for biochemical failure after radical prostatectomy
- Metabolite Profiling of Cheonggukjang, a Fermented Soybean Paste, Inoculated with Various Bacillus Strains during Fermentation
- Real-Time Observation of Single-Electron Movement through Silicon Single-Electron Transistor
- Age-Dependent Changes in Iron Deposition in the Gerbil Hippocampus
- ラット主嗅球におけるカルレチニン陽性傍糸球体細胞(Periglomerular cells)の生後変化(解剖学)
- Seizure-induced changes of mineralocorticoid and glucocorticoid receptors in the hippocampus in seizure sensitive gerbils
- Changes in Na^+-K^+-Cl^- cotransporter immunoreactivity in the gerbil hippocampus following spontaneous seizure
- Study on the Ophthalmic Diseases in ICR Mice and BALB/c Mice
- Spontaneous Ophthalmic Diseases in 586 New Zealand White Rabbits
- Inhibition of IL-8 Production by Green Tea Polyphenols in Human Nasal Fibroblasts and A549 Epithelial Cells(Pharmacology)
- Comparison of Density and Morphology of Neuroblasts in the Dentate Gyrus among Variously Aged Dogs, German Shepherds(Anatomy)
- Reduction of Calbindin D-28k-Immunoreactive Neurons in the Dog Dentate Gyrus
- Differential effects and changes of ceruloplasmin in the hippocampal CA1 region between adult and aged gerbils after transient cerebral ischemia
- Berberry Extract Reduces Neuronal Damage and N-Methyl-D-aspartate Receptor 1 Immunoreactivity in the Gerbil Hippocampus after Transient Forebrain Ischemia(Molecular and Cell Biology)
- Mineralocorticoid and glucocorticoid receptor expressions in astrocytes and microglia in the gerbil hippocampal CA1 region after ischemic insult
- Elevated voltage gated Cl^- channel expression enhances fast paired-pulse inhibition in the dentate gyrus of seizure sensitive gerbil
- Up-regulation of P/Q-type voltage-gated Ca^ channel immunoreactivity within parvalbumin positive neurons in the rat hippocampus following status epilepticus
- The effect of topiramate on GABA_B receptor, vesicular GABA transporter and paired-pulse inhibition in the gerbil hippocampus
- Digital Logic Implementation of Wide-Range Frequency Linear Detector
- GC-MS Based Metabolite Profiling of Rice Koji Fermentation by Various Fungi
- Ginsenosides Rb1 and Rg1 Suppress Triglyceride Accumulation in 3T3-L1 Adipocytes and Enhance β-Cell Insulin Secretion and Viability in Min6 Cells via PKA-Dependent Pathways
- Changes in Na^+-K^+-Cl^- cotransporter immunoreactivity in the gerbil hippocampus following transient ischemia
- Ischemia-Related Changes in Galanin Expression in the Dentate Hilar Region after Transient Forebrain Ischemia in Gerbils
- Altered GABA_B receptor immunoreactivity in the gerbil hippocampus induced by baclofen and phaclofen, not seizure activity
- Expressional Changes of Neuropeptide Y and Cholecystokinin in the Arcuate and Paraventricular Nuclei after Capsaicin Administration
- Improvement of Fuzzy ARTMAP Performance in Noisy Input Environment Using Weighted-Average Learning
- Effects of Electroacupuncture at Zusanli and Baihui on Brain-Derived Neurotrophic Factor and Cyclic AMP Response Element-Binding Protein in the Hippocampal Dentate Gyrus
- Species-Difference of Cyclooxygenase-2 in the Hippocampus of Rodents
- Effects of High Cholesterol Diet on Newly Generated Cells in the Dentate Gyrus of C57BL/6N and C3H/HeN Mice
- Immunohistochemical Changes in Orexigenic and Anorexigenic Neuropeptides in the Rat Hypothalamus after Capsaicin Administration
- Afferent Innervation of the Rat Pancreas : Retrograde Tracing and Immunohistochemistry in the Dorsal Root Ganglia
- Ribosomal Protein S3 Immunoreactivity in the Young, Adult and Aged Gerbil Hippocampus
- Anatomy: Ribosomal Protein S3 Immunoreactivity in the Young, Adult and Aged Gerbil Hippocampus
- Wnt signaling stabilizes the DIXDC1 protein through decreased ubiquitin-dependent degradation
- Differential Effects of Treadmill Exercise on Calretinin Immunoreactivity in Type 2 Diabetic Rats in Early and Chronic Diabetic Stages
- Effects of S-Allyl-L-Cysteine on Cell Proliferation and Neuroblast Differentiation in the Mouse Dentate Gyrus
- A Correlation between Antioxidant Activity and Metabolite Release during the Blanching of Chrysanthemum coronarium L.
- Transplantation of Adipose-Derived Stem Cells Promotes Formation of Prefabricated Flap in a Rat Model
- Inhibitory Effects of Calycosin Isolated from the Root of Astragalus membranaceus on Melanin Biosynthesis(Pharmacognosy)
- Mucinous Eccrine Nevus
- Acute Generalized Exanthematous Pustulosis in a Six-Year-Old Boy
- Association of p16^ hypermethylation with hepatitis B virus X protein expression in the early stage of HBV-associated hepatocarcinogenesis
- Case of congenital esophageal stricture by ganglioneuroma and acro-flexural hyperpigmentation : A coincidence?
- Neuronal Degeneration and Microglial Activation in the Ischemic Dentate Gyrus of the Gerbil
- Risk factors for the different types of chronic lung diseases of prematurity according to the preceding respiratory distress syndrome
- Clinical characteristics of chronic lung disease without preceding respiratory distress syndrome in preterm infants
- A Method for Studying the Electric Field Enhanced Emission of Carriers from Deep Levels
- Narrow-band Stokes Wave Generation and Amplification in a Pulsed Fiber Raman Laser Using a Double-pass Scheme
- Correlation between Antioxidative Activities and Metabolite Changes during Cheonggukjang Fermentation
- Cystadenoma of the seminal vesicle
- IS-74 A clinical study of depression symptoms during pregnancy(Group9 Perinatology2,International Session)
- A Hyperthyroid Patient with Graves' Disease Who Was Strongly Resistant to Methimazole : Investigation on Possible Mechanisms of the Resistance
- Cytopathology of Cervical Cancer in Korea
- Recovery from tanning induced by narrow-band UVB phototherapy in brown-skinned individuals with psoriasis : Twelve-month follow-up
- Junctionless Ge p-Channel Metal--Oxide--Semiconductor Field-Effect Transistors Fabricated on Ultrathin Ge-on-Insulator Substrate
- N-Acetylserotonin Increases Cell Proliferation and Differentiating Neuroblasts with Tertiary Dendrites through Upregulation of Brain-Derived Neurotrophic Factor in the Mouse Dentate Gyrus
- Metabolite Profiling of Cheonggukjang, a Fermented Soybean Paste, Inoculated with Various Bacillus Strains during Fermentation
- Calcinosis cutis of the fingertip associated with Raynaud's phenomenon
- Eruptive pseudoangiomatosis
- Plasma Cell Cheilitis Treated with Intralesional Injection of Corticosteroids
- Ginsenosides Rb1 and Rg1 Suppress Triglyceride Accumulation in 3T3-L1 Adipocytes and Enhance β-Cell Insulin Secretion and Viability in Min6 Cells via PKA-Dependent Pathways
- Effect of Pulse Frequency on Corrosion Behavior of AZ91 Mg Alloy Treated by Microarc Discharge Oxidation Coating
- Correlation between Antioxidative Activities and Metabolite Changes during Cheonggukjang Fermentation
- A Correlation between Antioxidant Activity and Metabolite Release during the Blanching of Chrysanthemum coronarium L.
- GC-MS Based Metabolite Profiling of Rice Koji Fermentation by Various Fungi
- Transplantation of Adipose Stromal Cells Promotes Neovascularization of Random Skin Flaps
- High-Electron-Mobility Ge n-Channel Metal-Oxide-Semiconductor Field-Effect Transistors with High-Pressure Oxidized Y_2O_3
- Observations of a Kelvin-Helmholtz Billow in the Ocean
- Epidemiological characteristics of genital herpes and condyloma acuminata in patients presenting to urologic and gynecologic clinics in Korea
- Do Escherichia coli extract and cranberry exert preventive effects on chronic bacterial prostatitis? Pilot study using an animal model
- EM2-3: Experimental and Numerical Investigation on the Urea SCR Dosing System to Improve NO_x Reduction Efficiency(EM: Exhaust Emission Control and Measurement,General Session Papers)
- Variation of Surface Roughness on Ge Substrate by Cleaning in Deionized Water and its Influence on Electrical Properties in Ge MetalOxideSemiconductor Field-Effect Transistors
- Tubular anomalous bones found in both thighs of a long-tailed macaque (Macaca fascicularis)
- Prevalence of sexually transmitted infections and sexual behavior of young adults and middle-aged people presenting to health examination centers in Korea
- Comparing the Effects of Acupuncture and Electroacupuncture at Zusanli and Baihui on Cell Proliferation and Neuroblast Differentiation in the Rat Hippocampus
- Changes in Cyclooxygenase-2 Immunoreactivity in the Hippocampus in a Model of Streptozotocin-Induced Type 1 Diabetic Rats
- Metabolomics-Based Optimal Koji Fermentation for Tyrosinase Inhibition Supplemented with Astragalus Radix
- Experimental and Analytical Characterization of Dual-Gated Germanium Junctionless p-Channel Metal--Oxide--Semiconductor Field-Effect Transistors
- 癲癇抵抗性及び感受性スナネズミの海馬における小膠細胞及び星状膠細胞マーカータンパク質の特異的免疫反応性
- Oxidation Rate Reduction of Ge with O_2 Pressure Increase
- Simultaneous Bilateral Stenosis of the Vertebral Arteries Treated by Unilateral Decompression: A Case Report
- Impact of diabetes mellitus on recurrence and progression in patients with non-muscle invasive bladder carcinoma : A retrospective cohort study