成犬ならびに老犬の歯状回と海馬におけるグリア線維酸性蛋白免疫染色性の変化(解剖学)
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概要
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星状膠細胞は,中枢神経系において神経細胞の支持,修復ならびに瘢痕形成過程に関与する.本研究では,星状膠細胞のマーカーであるグリア線維酸性蛋白(GFAP)の免疫染色像を,成犬(2-3歳)ならびに老犬(10-12歳)の歯状回ならびに海馬(CA1-3領域)で観察した.成犬において,GFAP陽性星状膠細胞は歯状回全層と錐体細胞層を除くCA1-3領域に分布していた.老犬では,GFAP陽性星状膠細胞は歯状回分子層で顕著に減少した.しかし,CA1-3領域のGFAP陽性細胞は全層で増数し,とくに細胞質が肥大していた,老犬のGFAP蛋白レベルは歯状回で減弱するものの,CA1-3領域で増大していた.これらの結果は,海馬歯状回とCAl1領域の星状膠細胞の形態ならびにGFAP蛋白量は年齢とともに変化することを示す.
- 2008-09-25
著者
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HWANG In
Department of Anatomy and Cell Biology, College of Veterinary Medicine and BK21 Program for Veterina
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CHOI Jung
Department of Anatomy and Neurobiology, College of Medicine, Hallym University
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LI Hua
Department of Anatomy and Neurobiology, College of Medicine, Hallym University
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YOO Ki-Yeon
Department of Anatomy and Neurobiology, College of Medicine, Hallym University
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KIM Dae
Central Research Institute, Natural F & P Co., Ltd.
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LEE Choong
Department of Anatomy and Cell Biology, College of Veterinary Medicine and BK21 Program for Veterina
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YI Sun
Department of Anatomy and Cell Biology, College of Veterinary Medicine and BK21 Program for Veterina
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SEONG Je
Department of Anatomy and Cell Biology, College of Veterinary Medicine and BK21 Program for Veterina
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LEE In
Department of Anatomy and Cell Biology, College of Veterinary Medicine and BK21 Program for Veterina
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YOON Yeo
Department of Anatomy and Cell Biology, College of Veterinary Medicine and BK21 Program for Veterina
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WON Moo-Ho
Department of Anatomy and Neurobiology, College of Medicine, Hallym University
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Won Moo
Department Of Anatomy And Neurobiology College Of Medicine Hallym University:institute Of Neurodegen
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Seong Je
Department Of Anatomy And Cell Biology College Of Veterinary Medicine And Bk21 Program For Veterinar
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Hwang In-koo
Department Of Anatomy And Cell Biology College Of Veterinary Medicine And Bk21 Program For Veterinar
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Kim Dong-woo
Central Research Institute Natural F&p Co. Ltd.
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Park Dong
Department Of Applied Biology And Chemistry Konkuk University
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Hwang In
韓国
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Yoo Ki-yeon
Department Of Anatomy College Of Medicine Hallym University
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Kim Yo
Department Of Anatomy And Cell Biology College Of Veterinary Medicine And Bk21 Program For Veterinar
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Hwang In
Department Of Anatomy And Cell Biology College Of Veterinary Medicine And Bk21 Program For Veterinar
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Lee I
Seoul National Univ. Seoul
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Lee I.
Department Of Anatomy And Cell Biology College Of Veterinary Medicine And Bk21 Program For Veterinar
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Yoon Yeo
Department Of Anatomy And Cell Biology College Of Veterinary Medicine And Bk21 Program For Veterinar
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Lee Choong
Department Of Anatomy And Neurobiology College Of Medicine Hallym University
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Lee Choong
Department Of Anatomy And Cell Biology College Of Veterinary Medicine And Bk21 Program For Veterinar
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Yi Sun
Department Of Anatomy And Cell Biology College Of Veterinary Medicine And Bk21 Program For Veterinar
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Choi Jung
Department Of Anatomy And Neurobiology College Of Medicine Hallym University
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Li Hua
Hallym Univ. Chuncheon
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Nam Young
Department Of Anatomy College Of Veterinary Medicine And School Of Agricultural Biotechnology Seoul
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Kim Dong‐woo
Natural F&p Co. Ltd Cheongwon Kor
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Yoo Ki‐yeon
Hallym Univ. Chuncheon
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Kim Yeong-in
Department Of Neurology Kangnam St. Mary's Hospital The Catholic University Of Korea
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Yi S
Anatomy College Of Veterinary Medicine Kyungpook National University
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Yoon Yeo-sung
Department Of Anatomy And Cell Biology College Of Veterinary Medicine And Bk21 Program For Veterinar
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Park Dong
Department Of Biochemistry Kon-kuk University
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Lee Heungshik
Department Of Anatomy College Of Veterinary Medicine And School Of Agricultural Biotechnology Seoul
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Lee In
Department Of Agronomy College Of Agriculture And Life Sciences Kyungpook National University
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Seong Je
Department Of Anatomy And Cell Biology College Of Veterinary Medicine And Bk21 Program For Veterinar
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Yi Sun
Department Of Anatomy And Cell Biology College Of Veterinary Medicine And Bk21 Program For Veterinar
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Kim Dae
Central Research Institute Natural F&p Co. Ltd.
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Lee In
Department Of Aerospace Engineering
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Yoo Ki-yeon
Department Of Anatomy And Cell Biology College Of Veterinary Medicine And Bk21 Program For Veterinar
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Choi Jung
Department Of Agricultural Biotechnology Seoul National University
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Won M.H.
Department of Anatomy and Neurobiology, College of Medicine, Hallym University:Institute of Neurodegeneration and Neuroregeneration, Hallym University
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Hwang In
Department of Anatomy and Cell Biology, College of Veterinary Medicine and BK21 Program for Veterinary Science, Seoul National University
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WON Moo-Ho
Department of Anatomy and Neurobiology, and Institute of Neurodegeneration and Neuroregeneration, College of Medicine, Hallym University
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LI Hua
Department of Anatomy and Neurobiology, and Institute of Neurodegeneration and Neuroregeneration, College of Medicine, Hallym University
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