Comparison of Density and Morphology of Neuroblasts in the Dentate Gyrus among Variously Aged Dogs, German Shepherds(Anatomy)
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概要
- 論文の詳細を見る
Neural progenitor cells in the dentate subgranular zone (SGZ) produce new cells all through life via proliferation. We observed differences in neuroblasts using doublecortin (DCX, a marker of neuronal differentiation) in the SGZ in variously aged dogs (German shepherds). In the 1-year-old group, DCX-immunoreactive (^+) cells were abundantly observed in the SGZ: These cells had processes extending into the molecular layer. In the 3-year-old group, DCX^+ cells were decreased by 53.0% compared to that in the 1-year-old group, and DCX^+ processes were also markedly decreased. In the 6 and 8-year-old groups, DCX^+ cells were decreased by 34.3% and 62.9% vs. the pre-aged group. In the 8-year-old group, DCX^+ cells were decreased by 86.4% compared to that in the 1-year-old group. In the 12-year-old group, DCX^+ cells and processes were nearly disappeared. This suggests that DCX^+ cells processes significantly decreased at 3 years in the SGZ of the German shepherd.
- 社団法人日本獣医学会の論文
- 2009-02-25
著者
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HWANG In
Department of Anatomy and Cell Biology, College of Veterinary Medicine and BK21 Program for Veterina
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CHOI Jung
Department of Anatomy and Neurobiology, College of Medicine, Hallym University
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YOO Ki-Yeon
Department of Anatomy and Neurobiology, College of Medicine, Hallym University
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LEE Choong
Department of Anatomy and Cell Biology, College of Veterinary Medicine and BK21 Program for Veterina
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WON Moo-Ho
Department of Anatomy and Neurobiology, College of Medicine, Hallym University
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Won Moo
Department Of Anatomy And Neurobiology College Of Medicine Hallym University:institute Of Neurodegen
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Hwang In-koo
Department Of Anatomy And Cell Biology College Of Veterinary Medicine And Bk21 Program For Veterinar
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Hwang In
韓国
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Yoo Ki-yeon
Department Of Anatomy College Of Medicine Hallym University
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Kim Yo
Department Of Anatomy And Cell Biology College Of Veterinary Medicine And Bk21 Program For Veterinar
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Hwang In
Department Of Anatomy And Cell Biology College Of Veterinary Medicine And Bk21 Program For Veterinar
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Lee Choong
Department Of Anatomy And Neurobiology College Of Medicine Hallym University
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Park Ok
Department Of Anatomy And Neurobiology College Of Medicine Hallym University
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Lee Choong
Department Of Anatomy And Cell Biology College Of Veterinary Medicine And Bk21 Program For Veterinar
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Choi Jung
Department Of Anatomy And Neurobiology College Of Medicine Hallym University
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Nam Young
Department Of Anatomy College Of Veterinary Medicine And School Of Agricultural Biotechnology Seoul
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Yoo Ki‐yeon
Hallym Univ. Chuncheon
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Kim Yeong-in
Department Of Neurology Kangnam St. Mary's Hospital The Catholic University Of Korea
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Yoo Ki-yeon
Department Of Anatomy And Cell Biology College Of Veterinary Medicine And Bk21 Program For Veterinar
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Choi Jung
Department Of Agricultural Biotechnology Seoul National University
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Won M.H.
Department of Anatomy and Neurobiology, College of Medicine, Hallym University:Institute of Neurodegeneration and Neuroregeneration, Hallym University
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Hwang In
Department of Anatomy and Cell Biology, College of Veterinary Medicine and BK21 Program for Veterinary Science, Seoul National University
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WON Moo-Ho
Department of Anatomy and Neurobiology, and Institute of Neurodegeneration and Neuroregeneration, College of Medicine, Hallym University
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