Changes in Cyclooxygenase-2 Immunoreactivity in the Hippocampus in a Model of Streptozotocin-Induced Type 1 Diabetic Rats
スポンサーリンク
概要
- 論文の詳細を見る
In this study, we investigated diabetic stage dependent cyclooxygenase-2 (COX-2) immunoreactivity in the dentate gyrus in streptozotocin (STZ)-induced type 1 diabetic rats. The animals were sacrificed at 2, 3 and 4 weeks after STZ treatment. Blood glucose levels were increased after STZ treatment. COX-2 immunoreactivity in dentate gyrus was significantly increased in these regions 3 weeks after STZ treatment and restored to its basal level to 4 weeks after STZ treatment. In contrast, COX-2 immunoreactivity was not changed in CA3 region in all groups. These results suggest that STZ-induced type 1 diabetes transiently, but not permanently, decreased synaptic transmission and plasticity 3 weeks after STZ treatment in the dentate gyrus.
著者
-
Seong Je
Department Of Anatomy And Cell Biology College Of Veterinary Medicine And Bk21 Program For Veterinar
-
Yoo Dae
Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for V
-
Hwang In
Department Of Anatomy And Cell Biology College Of Veterinary Medicine And Bk21 Program For Veterinar
-
Yoon Yeo
Department Of Anatomy And Cell Biology College Of Veterinary Medicine And Bk21 Program For Veterinar
-
Yi Sun
Department Of Anatomy And Cell Biology College Of Veterinary Medicine And Bk21 Program For Veterinar
-
Choi Jung
Department Of Anatomy And Neurobiology College Of Medicine Hallym University
-
KIM Woosuk
Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for V
-
Yi S
Anatomy College Of Veterinary Medicine Kyungpook National University
-
Nam Sung
Department Of Pharmacy Ewha Womans University
-
Choi Jung
Department Of Agricultural Biotechnology Seoul National University
-
HWANG In
Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University
-
YOON Yeo
Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University
-
NAM Sung
Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University
-
CHOI Jung
Department of Anatomy, College of Veterinary Medicine, Kangwon National University
-
YOO Dae
Department of Anatomy and Cell Biology, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University
-
YOO Dae
Department of Anatomy and Cell Biology, College of Veterinary Medicine and BK21 Program for Veterinary Science, Seoul National University
関連論文
- 成犬ならびに老犬の歯状回と海馬におけるグリア線維酸性蛋白免疫染色性の変化(解剖学)
- 癲癇抵抗性及び感受性スナネズミの海馬における小膠細胞及び星状膠細胞マーカータンパク質の特異的免疫反応性(解剖学)
- 一過性大脳虚血を施したスナネズミ皮質体性感覚野におけるGlutamic acid decarboxylase 67免疫反応性ならびにタンパク質レベルの一過性増加(解剖学)
- 癪癇感受性スナネズミの視床下部室旁核におけるTyrosine hydroxylaseの減少(解剖学)
- スナネズミ十二指腸の筋層間神経叢におけるカルビンジンD-28k陽性ニューロンの年齢に伴う変化(解剖学)
- Gliosis in the Amygdala Following Myocardial Infarction in the Rat
- スナネズミ海馬CA1領域におけるイオン化カルシウム結合アダプター分子1の免疫反応性及びタンパクレベルの年齢に伴う変化(解剖学)
- 種々月齢の特発性高血圧ラット歯状回におけるDoublecortin陽性神経前駆細胞 : SDラットとの比較について(解剖学)
- 成犬と老犬の海馬CA1領域における脂質過酸化反応とCu,Zn-superoxide dismutaseの違い(解剖学)
- Comparison of α-synuclein immunoreactivity and protein levels in ischemic hippocampal CA1 region between adult and aged gerbils and correlation with Cu,Zn-superoxide dismutase
- Anatomy: Effects of electroacupuncture at Zusanli and Baihui on brain-derived neurotrophic factor and cyclic AMP response element-binding protein in the hippocampal dentate gyrus
- Effects of Methimazole on the Onset of Type 2 Diabetes in Leptin Receptor-Deficient Rats(Laboratory Animal Science)
- Effects of Ginkgo biloba Extract on Promotion of Neurogenesis in the Hippocampal Dentate Gyrus in C57BL/6 Mice
- Fluorescent Calix[4]arene-appended Silica Nanotubes as Selective Chemosensor and Adsorbent for Pb^ Ion
- A Study of a Regeneration Reaction for Desulfurization Sorbents Using Natural Manganese Ore
- Antimutagenicity and Cytotoxicity of the Constituents from the Aerial Parts of Rumex acetosa(Pharmacognosy)
- ウサギの内臓表面で観察されたボンハン管とボンハン小体の組織学的特徴
- Perineural invasion is a prognostic factor for biochemical failure after radical prostatectomy
- Age-Dependent Changes in Iron Deposition in the Gerbil Hippocampus
- ラット主嗅球におけるカルレチニン陽性傍糸球体細胞(Periglomerular cells)の生後変化(解剖学)
- Seizure-induced changes of mineralocorticoid and glucocorticoid receptors in the hippocampus in seizure sensitive gerbils
- Histological aspect of threadlike structure inside blood vessel(International Conference on Mind Body Science : Physical and Physiological Approach joint with The Eighteenth Symposium on Life Information Science)
- Comparison of Density and Morphology of Neuroblasts in the Dentate Gyrus among Variously Aged Dogs, German Shepherds(Anatomy)
- Reduction of Calbindin D-28k-Immunoreactive Neurons in the Dog Dentate Gyrus
- Differential effects and changes of ceruloplasmin in the hippocampal CA1 region between adult and aged gerbils after transient cerebral ischemia
- Berberry Extract Reduces Neuronal Damage and N-Methyl-D-aspartate Receptor 1 Immunoreactivity in the Gerbil Hippocampus after Transient Forebrain Ischemia(Molecular and Cell Biology)
- Mineralocorticoid and glucocorticoid receptor expressions in astrocytes and microglia in the gerbil hippocampal CA1 region after ischemic insult
- Elevated voltage gated Cl^- channel expression enhances fast paired-pulse inhibition in the dentate gyrus of seizure sensitive gerbil
- Changes in Na^+-K^+-Cl^- cotransporter immunoreactivity in the gerbil hippocampus following transient ischemia
- Nutrient Effects of FK-506,a New Immunosuppressant, Production by Streptomyces sp. in a Defined Medium
- Ischemia-Related Changes in Galanin Expression in the Dentate Hilar Region after Transient Forebrain Ischemia in Gerbils
- Altered GABA_B receptor immunoreactivity in the gerbil hippocampus induced by baclofen and phaclofen, not seizure activity
- 肥満型及び痩せ型Zucker糖尿病肥満ラットの視床下部におけるオレキシンA及びニューロペプタイドYの発現変化(解剖学)
- Expressional Changes of Neuropeptide Y and Cholecystokinin in the Arcuate and Paraventricular Nuclei after Capsaicin Administration
- 高脂肪飼料飼育ラットの脳におけるコレクトキニンとニューロペプチド発現に関するカプサイシンの効果(解剖学)
- Effects of Electroacupuncture at Zusanli and Baihui on Brain-Derived Neurotrophic Factor and Cyclic AMP Response Element-Binding Protein in the Hippocampal Dentate Gyrus
- Species-Difference of Cyclooxygenase-2 in the Hippocampus of Rodents
- Effects of High Cholesterol Diet on Newly Generated Cells in the Dentate Gyrus of C57BL/6N and C3H/HeN Mice
- Immunohistochemical Changes in Orexigenic and Anorexigenic Neuropeptides in the Rat Hypothalamus after Capsaicin Administration
- Ribosomal Protein S3 Immunoreactivity in the Young, Adult and Aged Gerbil Hippocampus
- Differential Effects of Treadmill Exercise on Calretinin Immunoreactivity in Type 2 Diabetic Rats in Early and Chronic Diabetic Stages
- Effects of S-Allyl-L-Cysteine on Cell Proliferation and Neuroblast Differentiation in the Mouse Dentate Gyrus
- Mucinous Eccrine Nevus
- Acute Generalized Exanthematous Pustulosis in a Six-Year-Old Boy
- Case of congenital esophageal stricture by ganglioneuroma and acro-flexural hyperpigmentation : A coincidence?
- Neuronal Degeneration and Microglial Activation in the Ischemic Dentate Gyrus of the Gerbil
- Risk factors for the different types of chronic lung diseases of prematurity according to the preceding respiratory distress syndrome
- Clinical characteristics of chronic lung disease without preceding respiratory distress syndrome in preterm infants
- A Method for Studying the Electric Field Enhanced Emission of Carriers from Deep Levels
- Narrow-band Stokes Wave Generation and Amplification in a Pulsed Fiber Raman Laser Using a Double-pass Scheme
- IS-74 A clinical study of depression symptoms during pregnancy(Group9 Perinatology2,International Session)
- BONE REGENERATIVE POLYMERIC BIOMATERIALS WITH DRUG RELEASING FUNCTION
- Cytopathology of Cervical Cancer in Korea
- Recovery from tanning induced by narrow-band UVB phototherapy in brown-skinned individuals with psoriasis : Twelve-month follow-up
- N-Acetylserotonin Increases Cell Proliferation and Differentiating Neuroblasts with Tertiary Dendrites through Upregulation of Brain-Derived Neurotrophic Factor in the Mouse Dentate Gyrus
- Calcinosis cutis of the fingertip associated with Raynaud's phenomenon
- Eruptive pseudoangiomatosis
- Plasma Cell Cheilitis Treated with Intralesional Injection of Corticosteroids
- Clinical Utility of Pleural Fluid NT-pro Brain Natriuretic Peptide (NT-proBNP) in Patients with Pleural Effusions
- Effect of Pulse Frequency on Corrosion Behavior of AZ91 Mg Alloy Treated by Microarc Discharge Oxidation Coating
- Correlation between Antioxidative Activities and Metabolite Changes during Cheonggukjang Fermentation
- A Correlation between Antioxidant Activity and Metabolite Release during the Blanching of Chrysanthemum coronarium L.
- GC-MS Based Metabolite Profiling of Rice Koji Fermentation by Various Fungi
- Significance of volcanogenic sediments in the Nogam Formation of the Pyeongan Group in Korea (South)
- In situ Hybridizationによる猫ヘルペスウイルス1検出の至適条件(病理学)
- Anatomy: Differential effects of treadmill exercise on calretinin immunoreactivity in type 2 diabetic rats in early and chronic diabetic stages
- EM2-3: Experimental and Numerical Investigation on the Urea SCR Dosing System to Improve NO_x Reduction Efficiency(EM: Exhaust Emission Control and Measurement,General Session Papers)
- Generation of reduced macrolide analogs by regio-specific biotransformation
- Comparing the Effects of Acupuncture and Electroacupuncture at Zusanli and Baihui on Cell Proliferation and Neuroblast Differentiation in the Rat Hippocampus
- Changes in Cyclooxygenase-2 Immunoreactivity in the Hippocampus in a Model of Streptozotocin-Induced Type 1 Diabetic Rats
- Metabolomics-Based Optimal Koji Fermentation for Tyrosinase Inhibition Supplemented with Astragalus Radix
- Biosynthesis of rapamycin and its regulation : past achievements and recent progress
- Possibility to Establish Chicken Stem Cell from Non-germline Tissue : Detection of Colony-forming Cells after Chicken Fibroblast Culture and Subsequent Stem Cell Characterization
- 癲癇抵抗性及び感受性スナネズミの海馬における小膠細胞及び星状膠細胞マーカータンパク質の特異的免疫反応性
- Real-Time Observation of Single-Electron Movement through Silicon Single-Electron Transistor
- Novel Quinolinylaminoisoquinoline Bioisosteres of Sorafenib as Selective RAF1 Kinase Inhibitors: Design, Synthesis, and Antiproliferative Activity against Melanoma Cell Line
- Memory Effect in an Aluminum Single-Electron Floating-Node Memory Cell
- Simultaneous Bilateral Stenosis of the Vertebral Arteries Treated by Unilateral Decompression: A Case Report
- Impact of diabetes mellitus on recurrence and progression in patients with non-muscle invasive bladder carcinoma : A retrospective cohort study
- Identification of a new phomoxanthone antibiotic from Phomopsis longicolla and its antimicrobial correlation with other metabolites during fermentation