Biotransformation of Isoflavones by the Larvae of the Common Cutworm (Spodoptera litura)

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概要

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• Biotransformation of the 5,7,4'-trimethoxyisoflavone (1), 6,7,4'-trimethoxyisoflavone (2), and 7,4-dime-thoxyisoflavone (3) by insects, Spodoptera litura was investigated. Compound 1 was transformed to 5-hydroxy-7,4'-dimethoxyisoflavone (4), 7-hydroxy-5,4'-dimethoxyisoflavone (5) and 4'-hydroxy-5,7-dimethoxyisoflavone (6) by S. litura. Compounds 2 and 3 were hardly metabolized by S. litura. This suggested that compound 1 was converted to compounds 4,5 and 6 by demethylation at the C-5, C-7 and C-4'position, respectively.

• 公益社団法人日本薬学会の論文
• 2006-05-01

著者

• Miyazawa Mitsuo

  Department Of Applied Chemistry Faculty Of Scienc Snd Engineering Kinki University

• Araki Hideo

  Fuji Oil Co. Ltd. Hannan R&d Center

• Takahashi Koji

  Department Of Chemistry And Chemical Engineering Yamagata University

• Miyazawa Mitsuo

  Department Of Aplied Chemistry Faculty Of Science And Engineering Kinki University

• Takahashi Koji

  Department Of Aeronautics And Astronautics Kyushu University

• Takahashi Koji

  Department Of Applied Chemistry Faculty Of Science And Engineering Kinki University

• TAKAHASHI Koji

  Departent of Materials Science and Engineering,Faculty of Engineering,Yamagata University

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