α-Glucosidase Inhibitor from Bergenia ligulata
スポンサーリンク
概要
- 論文の詳細を見る
Inhibitory compound of α-glucosidase activity, (+)-afzelechin (1), was isolated from rhizomes of Bergenia ligulata. The structure was identified by IR, EI-MS, 1H and 13C NMR spectroscopy. The ID50 (50% inhibition dose) value of compound 1 was 0.13 mM. To investigate the structure-activity relationship, (+)-afzelechin tetraacetate (2), (+)-5,7,4’-trimethoxyafzelechin (3), (+)-tetramethoxyafzelechin (4), and (+)-3-acetyl-5,7,4’-trimethoxyafzelechin (5) as the derivatives of compound 1 were evaluated as well.
- 日本油化学会の論文
著者
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MIYAZAWA Mitsuo
Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University
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OKUNO Yoshiharu
Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University
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Okuno Yoshiharu
Department Of Applied Chemistry Faculty Of Science And Engineering Kinki University
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Saijyo Junichi
Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University
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Suzuki Yousuke
Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University
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Yamaki Hidehiko
Koei Kogyo Co., Ltd.
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Suzuki Takuya
Koei Kogyo Co., Ltd.
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Miyazawa Mitsuo
Department Of Applied Chemistry Faculty Of Scienc Snd Engineering Kinki University
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Miyazawa Mitsuo
Department Of Aplied Chemistry Faculty Of Science And Engineering Kinki University
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