Synthesis of Compounds related to Antitumor Agents. IV. On the Reaction of Aromatic Carboxylates with 2,4-Diamino-5-hydroxy-6-methylpyrimidine

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概要

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• Attempts to prepare oxazolo [4,5-d] pyrimidines by the reaction of 2,4-diamino-5-hydroxy-6-methylpyrimidine (I) with aromatic carboxylates. The products were carbinolamines which were converted to oxazolo [4,5-d] pyrimidines. Also, the application of the Salol reaction of I gave 5-amino-2-(2,4-diamino-6-methylpyrimidin-5-yl)oxy-2-o-hydroxyphenyl-7-methyl-3H-oxazolo [4,5-d] pyrimidine (XI) which was an unusual product in this reaction.

• 社団法人日本薬学会の論文
• 1976-10-25

著者

• 加藤 哲夫

  Faculty Of Pharmaceutical Sciences Nagoya City University

• 織田 範一

  Faculty of Pharmaceutical Sciences, Nagoya City University

• 伊藤 磯雄

  Faculty of Pharmaceutical Sciences, Nagoya City University

• 伊藤 磯雄

  名古屋市立大学薬学部

• 織田 範一

  Faculty Of Pharmaceutical Sciences Nagoya City University

• 伊藤 磯雄

  Faculty Of Pharmaceutical Sciences Nagoya City University

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