Synthesis of Compounds related to Antitumor Agents. VI. The Conversion of 2,4-Dialkoxypyrimidines into N-Dialkyl-1,2,3,4-tetrahydro-2,4-dioxopyrimidines in the Presence of p-Toluenesulfonic Acid Derivatives

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概要

• 論文の詳細を見る

• The conversion of 2,4-dialkoxypyrimidines into 1,3-dialkyl-1,2,3,4-tetrahydro-2,4-dioxopyrimidines was brought about in the presence of p-toluenesulfonic acid derivatives by simple heating. This reaction seems to proceed stabilized transition state in p-toluenesulfonic acid derivatives, and may give rise to a nucleophilic reaction by nitrogen on the migrating alkyl group.

• 社団法人日本薬学会の論文
• 1977-02-25

著者

• 加藤 哲夫

  Faculty Of Pharmaceutical Sciences Nagoya City University

• 織田 範一

  Faculty of Pharmaceutical Sciences, Nagoya City University

• 伊藤 磯雄

  Faculty of Pharmaceutical Sciences, Nagoya City University

• 伊藤 磯雄

  名古屋市立大学薬学部

• 織田 範一

  Faculty Of Pharmaceutical Sciences Nagoya City University

• 伊藤 磯雄

  Faculty Of Pharmaceutical Sciences Nagoya City University

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