新規複素環キノン"Benzo[g]pyrido[2,1-b]quinazoline-6,11-dioneおよびBenzo[g]pyrazolo[3,2-b]quinazoline-5,10-diones"の合成
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概要
- 論文の詳細を見る
Ethyl 1,4-dihydro-1,4-dioxo-3-methoxy-2-naphthoate (I) is condensed with amidines, 2-aminopyridines and 3-aminopyrazole, to give new tetracyclic quinones (IIIa-c and VI) containing nitrogen atom and hydrogenation of IIIa and IIIb over Pd-C or Raney-Ni afforded 1,2,3,4-tetrahydro (IXa, b) or 1,2,3,4,7,8,9,10-octahydrobenzo[g]pyrido[2,1-b]quinazoline (Xa), respectively. Benzo[g]pyrido[2,1-b]quinazoline derivatives except for Xa showed inhibitory activities to S. aureus and T. interdigitale.
- 公益社団法人日本薬学会の論文
- 1983-04-25
著者
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織田 範一
Faculty of Pharmaceutical Sciences, Nagoya City University
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小林 和弘
名古屋市立大学薬学部
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榊原 仁作
名市大院薬
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織田 範一
名古屋市立大学薬学部
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織田 範一
Faculty Of Pharmaceutical Sciences Nagoya City University
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