Synthesis of Pyrazolone Derivatives. XIII. Synthesis of N, N-Dialkyl-N'-substituted-N'-[3 (4-substituted-2-methyl-5-oxo-1-phenyl-3-pyrazolin-3-yl) methyl] ethylenediamine

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概要

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• N, N-Dialkyl-N'-substituted-N'-[3 (4-substituted-2-methyl-5-oxo-1-phenyl-3-pyrazolin-3-yl) methyl] ethylenediamines (IIIa-IIIe) were prepared by reacting 3-bromomethyl-3-pyrazolin-5-ones (Ia and Ib) with ethylenediamines (IIa-IIc). Reaction of 4-(N-4-ethoxyphenyl) aminomethyl-3-pyrazolin-5-one (V) with dialkylaminoethylchloride afforded N, N-dialkyl-N'-(4-ethoxyphenyl) ethylenediamines (IIa and VII) or 4-ethoxy-N, N-bis [(2,3-dimethyl-1-phenyl-5-oxo-3-pyrazolin-4-yl) methyl] aniline (VIII).

• 公益社団法人日本薬学会の論文
• 1969-03-25

著者

• 伊藤 磯雄

  Faculty of Pharmaceutical Sciences, Nagoya City University

• 永井 慎一

  Faculty of Pharmaceutical Sciences, Nagoya City University

• 伊藤 磯雄

  Faculty Of Pharmaceutical Sciences Nagoya City University

関連論文

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