Synthesis of Compounds Related to Antitumor Agents. II. Studies on the Synthesis of Oxazolo [4,5-d] pyrimidine Nucleoside Derivatives

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概要

• 論文の詳細を見る

• 2,4-Diamino-6-methylpyrimidine (II) was synthesized from acetoacetonitrile (III) and guanidine which was then converted to 5-amino-7-methyloxazolo [4,5-d] pyrimidin-2(3H)-one(IX). Several nucleoside type compounds were synthesized by the condensation of IX with some halogenoacetyl and halogenobenzoyl sugars in the presence of metal salts as a halogen acceptor. The antitumor activity of the compounds was tested and found to be inactive.

• 社団法人日本薬学会の論文
• 1975-09-25

著者

• 加藤 哲夫

  Faculty Of Pharmaceutical Sciences Nagoya City University

• 太田 和雄

  Laboratory of Chemotherapy, Aichi Cancer Center, Research Institute

• 伊藤 磯雄

  名古屋市立大学薬学部

• 太田 和雄

  Laboratory Of Chemotherapy Aichi Cancer Center Research Institute

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