Reduction of N-(α-Acyl-2-quinolylmethyl) pyridinium Perchlorate

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概要

• 論文の詳細を見る

• The reductive cleavage of pyridinium group from N-(α-acyl-2-quinolylmethyl)-pyridinium perchlorate (I) was found to be effected by treatment of I with zinc powder in the presence of potassium acetate in acetic acid under relatively mild conditions to give quinaldyl ketone (II). The tautomeric structures (II-A, II-B and II-C) of aryl quinaldyl ketones (IIb-IIk) were examined by UV, NMR and IR spectroscopies, and it was made clear that II existed chiefly as the enaminic form (II-C) rather than the chelated enolic form (II-B), differently from the case of aryl 2-picolyl ketones (IV).

• 公益社団法人日本薬学会の論文
• 1970-05-25

著者

• 山崎 企善

  Faculty of Pharmaceutical Sciences, Fukuoka University

• 浜名 政和

  Faculty of Pharmaceutical Sciences, Kyushu University

• 野田 寛治

  Research Laboratories Hisamitsu Pharmaceutical Co. Inc.

• 浜名 政和

  Faculty Of Pharmaceutical Sciences Kyushu University

• 山崎 企善

  Faculty Of Pharmaceutical Sciences Fukuoka University

• 野田 寛治

  Faculty of Pharmaceutical Sciences, Fukuoka University

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