Studies on Tertiary Amine Oxides. XXVII. Reactions of Aromatic N-Oxides with Enamines of Cyclohexanone in the Presence of Acylation Agents : Reaction of α-and γ-Methyl-pyridine and -quinoline N-Oxides
スポンサーリンク
概要
- 論文の詳細を見る
Reactions of α-and γ-methyl-pyridine and -quinoline N-oxides with enamines of cyclohexanone in the presence of and acylating agent were examined. From N-oxides of 2-picoline (IV), 4-picoline (V) and lepidine (X), the corresponding 2-(2-heterocyclyl)-cyclohexanones (VI, VII, XI) were obtained in good yields. The reaction of quinaldine 1-oxide (XIII) followed two kinds of courses, producing 2-(2-methyl-4-quinolyl) cyclohexanone (XV, XVI ; 38.2%) accompanied with 3-tosyloxy-(XIVa ; 47%) and 3-chloroquinaldine (XIVb ; 2.7%).
- 公益社団法人日本薬学会の論文
- 1966-07-25
著者
-
野田 浩司
産業医科大学薬剤部
-
野田 浩司
Faculty of Pharmaceutical Sciences, Kyushu University
-
浜名 政和
Faculty Of Pharmaceutical Sciences Kyushu University
関連論文
- Studies on Tertiary Amine Oxides. LVII. Re-examination of the Reaction of Quinoline 1-Oxide with Acetic Anhydride, and the Related Reactions
- Studies on Tertiary Amine Oxides LXXXII. : The Reaction of 1-Oxido-4(or 2)-pyridinediazonium Tetrafluoroborate with Olefins in the Presence of Palladium Complex
- Studies on Tertiary Amine Oxides. LXXVII. The Pseudo-Gomberg Reaction of 4-and 2-Aminopyridine 1-Oxides
- Reduction of 1-Methyl-3-and-4-methoxycarbonyl Pyridinium Iodide with Sodium Borohydride
- Studies on Tertiary Amine Oxides. XLIII. Reactions of Aromatic N-Oxides with Alkoxyindoles in the Presence of Acylating Agents
- Studies on Tertiary Amine Oxides. XL. Reactions of Aromatic N-Oxides with Oxindoles in the Presence of Acylating Agents
- Studies on Tertiary Amine Oxides. XXXIX. Reactions of Aromatic N-Oxides with Indoles in the Presence of Acylating Agents
- Reaction of Aromatic N-Oxides with Indoles in the Presence of an Acylating Agent
- Synthese von Derivaten der Cinchona-Alkaloide. XXXIII. Synthese von 2'-Cyanoderivaten der Alkaloide der Chinin-Reihe
- 過硫酸アンモニウム存在下におけるQuinolinium Perchlorate類のα-オキシアルキル化反応
- Studies on Tertiary Amine Oxides. LXIX. Reactions of 2-Chloromethylquinoline Derivatives with 2-Nitropropane
- Studies on Tertiary Amine Oxides. LXII. A Novel Formation of Quinolinium Methylides by the Reaction of Quinoline 1-Oxides with Active Methylene Compounds in the Presence of an Acylating Agent
- Studies on Tertiary Amine Oxides. XIV. Reactions of N-(p-Dimethylaminophenyl) nitrones having Pyridine, Quinoline or its N-Oxide, as α-Substituent with Carbon Disulfide.
- Studies on Tertiary Amine Oxides. XIII. Reactions of N-(p-Dimethylaminophenyl) nitrones having Pyridine N-Oxide, Quinoline or its N-Oxide as α-Substituent.
- Studies on Tertiary Amine Oxides. XLIV. Reactions of Aromatic N-Oxides with N-Acylmethylpyridinium Salts in the Presence of Acylating Agents
- Studies on Azole Compounds. III. Reactions of Oxazole N-Oxides with Phosphoryl Chloride and Acetic Anhydride
- Reduction of N-(α-Acyl-2-quinolylmethyl) pyridinium Perchlorate
- Studies on Tertiary Amine Oxides. LXI. Some Reactions of 2-Phenylquinoline 1-Oxide and Its Derivatives
- 2-(2-Quinolyl)-または2-(2-Pyridyl)cyclohexanoneと有機過酸との反応
- Beckmann転位条件下における2-(2-Quinolyl)-または2-(2-Pyridyl)-cyclohexanone Oximeの新しい閉環反応
- Studies on Tertiary Amine Oxides. LXXXI. Formation of 1-lsoquinoliniomethylides by the reaction of Isoquinoline 2-Oxide with Cyanoacetic Acid and Benzoylacetonitrile in the Presence of Acetic Anhydride
- Studies on Tertiary Amine Oxides. LXXX. Reaction of Quinoline 1-Oxide with Phenylacetic Anhydride
- Studies on Tertiary Amine Oxides. XXXVIII. Reaction of Quinoline 1-Oxide with N-Acylmethylpyridinium Salts in the Presence of Acylating Agents
- The Pseudo-Gomberg Reaction of Benzene Derivatives with 1-Substituted Pyrroles
- A New Synthetic Approach to 8-Chloroflavins and Their Conversion into 8-(Substituted-amino) flavins
- Studies on Tertiary Amine Oxides. LIX. A New Total Synthesis of dl-Allomatridine
- Studies on Tertiary Amine Oxides. LVIII. Reactions of Substituted Dehydroquinolizidines with Pyridine N-Oxide. (2)
- Studies on Tertiary Amine Oxides. LXXIII. Substitution of Aromatic N-Oxides with Radicals produced from Azo Compounds
- Studies on Tertiary Amine Oxides. LV. Reactions of N-Alkoxyquinolinium Salts with Enamines of Ketones. (1)
- Studies on Tertiary Amine Oxides. LXVI. Reactions of Quinoline 1-Oxide Derivatives with Tosyl Chloride in the Presence of Triethylamine
- Studies of Tertiary Amine Oxides. LXV. Reaction of Quinoline 1-Oxide with Tosyl Chloride in the Presence of Triethylamine
- Studies on Tertiary Amine Oxides. LXXIX. Reactions of 2-Ethoxycarbonyl-1-hydroxyindole in the Presence of Acylating Agents
- The Reaction of α-Substituted Ketones with N-Alkylhydroxylamines
- Studies on Tertiary Amine Oxides. LXXVI. Reactions of Aromatic N-Oxides with 1,3-Cyclohexanediones in the Presence of Acetic Anhydride
- Studies on Tertiary Amine Oxides. LXXIV. Reactions of Aromatic N-Oxides with 2-Phenyl-2-Thiazolin-4-one in the Presence of Acetic Anhydride
- Studies on Tertiary Amine Oxides. LXXII. Some Nucleophilic Reactions of 1-Hydroxy-2-phenylindole
- Studies on Tertiary Amine Oxides. LXXI. Some Electrophilic Reactions of 1-Hydroxy-2-phenylindole
- Stereoselective Alkylation of 1-Oxoquinolizidine
- 第3級アミンオキシドに関する研究(第60報) : アシル化剤の存在下における3,2'-Diquinolyl 1-Oxideと求核剤との反応
- Studies on Tertiary Amine Oxides. XXXVII. Reactions of Aromatic N-Oxides with Enol Ethers in the Presence of Benzoyl Chloride
- Photoreaction of N-Ethoxyquinolinium Perchlorate in Methanol
- 第3級アミンオキシドに関する研究(第36報) : アシル化剤の存在下における芳香族アミンオキシドと1-Morpholinoisobuteneとの反応
- Studies on Tertiary Amine Oxides. XXXI. Reactions of Aromatic N-Oxides with Antipyrine in the Presence of Acylating Agents.
- Reactions of Aromatic N-Oxides with Enamines of Cyclohexanone in the Presence of Acylating Agents (3).Reactions of Chloro- and Hydroxy-pyridine and -quinoline N-Oxides
- Studies on Tertiary Amine Oxides. XXVII. Reactions of Aromatic N-Oxides with Enamines of Cyclohexanone in the Presence of Acylation Agents : Reaction of α-and γ-Methyl-pyridine and -quinoline N-Oxides
- Studies on Tertiary Amine Oxides. XXIV. Reactions of Aromatic N-Oxides with Enamines of Cyclohexanone in the Presence of Acylating Agents (1)
- Reactions of Quinoline 1-Oxide with Enamines of Cyclohexanone
- Studies on Tertiary Amine Oxides. LXIV. Reaction of 4-Nitroquinoline 1-Oxide and Related Compounds with Potassium Cyanide
- Studies on Tertiary Amine Oxides. LIV. Reaction of Quinoline N-Oxides with Potassium Cyanate and Tosyl Chloride in Ethanol
- Studies on Tertiary Amine Oxides. XLVII. Reaction of Quinoline 1-Oxide Derivatives with Cyanogen Bromide
- Studies on Tertiary Amine Oxides. XLV. Reaction of Quinoline N-Oxide with Cyanogen Bromide
- Studies on Tertiary Amine Oxides. XXVI. Nitration of 6-Substituted Quinoline 1-Oxides.
- Studies on Tertiary Amine Oxides. XLIX. Reactions of Pyridine and Quinoline N-Oxides with 1 (10)-Dehydroquinolizidine