Studies on Azole Compounds. II. Reaction of Oxazole N-Oxides with Phenylisocyanate to give Imidazole Derivatives
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概要
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The reactions of 4-methyloxazole N-oxides substituted in the 2-position (Ia-d) with phenylisocyanate were studied. The oxazole N-oxides were easily attacked on the 2-position by the nitrogen of phenylisocyanate, followed by ring-cleavage and re-cyclization to give 5-hydroxy-4-methylene-1,2,5-trisubstituted 4,5-dihydroimidazoles (IIa-d). The structures of IIa-d were determined by their chemical behavior and spectral data.
- 公益社団法人日本薬学会の論文
- 1970-10-25
著者
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後藤 良宣
Faculty of Pharmaceutical Sciences, Fukuoka University
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山崎 企善
Faculty of Pharmaceutical Sciences, Fukuoka University
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本庄 紀子
Faculty of Pharmaceutical Sciences, Fukuoka University
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山崎 企善
Faculty Of Pharmaceutical Sciences Fukuoka University
-
後藤 良宣
Faculty Of Pharmaceutical Sciences Fukuoka University
-
本庄 紀子
Faculty Of Pharmaceutical Sciences Fukuoka University
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