DEVELOPMENT OF A NEW N^π-PROTECTING GROUP FOR HISTIDINE, N^π-1-ADAMANTYLOXYMETHYLSHISTIDINE

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概要

• 論文の詳細を見る

• N^π-1-Adamantyloxymethylhistidine, His(N^π-1-Adom) was prepared, and the properties of the 1-Adom group were examined. 1-Adom group can be easily removed by TFA ; it is stable to 20% piperidine/DMF and 1N NaOH. His(N^π-1-Adom) derivatives can suppress racemization during coupling reaction. TRH was synthesized using His(N^π-1-Adom), successfully.

• 公益社団法人日本薬学会の論文
• 1996-04-15

著者

• OKADA Yoshio

  Faculty of Pharmaceutical Sciences, Kobe Gakuin University

• Okada Yoshio

  Faculty Of Pharmaceutical Sciences Kobe Gakuin University

• YOKOI Toshio

  The Graduate School of Food and Medicinal Sciences, Kobe Gakuin University

• MU Yu

  Faculty of Pharmaceutical Sciences, Osaka University

• Mu Y

  Faculty Of Pharmaceutical Sciences Kobe Gakuin University

• Mu Yu

  Faculty Of Pharmaceutical Sciences Kobe Gakuin University

• Wang J

  Shenyang Pharmaceutical Univ. Shenyang Chn

• Yokoi T

  Faculty Of Pharmaceutical Sciences And High-technology Research Center Kobe-gakuin University

• Yokoi T

  Kobe‐gakuin Univ. Hyogo Jpn

• YAMAMOTO Takeshi

  Faculty of Engineering, Kobe University

• Yamamoto T

  R&d Laboratories Nippon Organon K.k.

• WANG Jidong

  Faculty of Pharmaceutical Sciences, Kobe Gakuin University

• Wang J

  Department Of Synchrotron Radiation Science The Graduate University For Advanced Studies

• Yokoi T

  Fucunlty Of Pharmaceutical Sciences Kobe Gakuin University

• Yamamoto Takeshi

  Faculty Of Agriculture Kochi University

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