Amino Acids and Peptides. XLVI. Introduction of Carboxyl Function into Pyrazinone by Using Newly Developed Procedure for pyrazinone Ring Formation : Observation of Immediate Decarboxylation

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概要

• 論文の詳細を見る

• The carboxyl function was easily introduced into a pyrazinone ring by means of a newly developed procedure for pyrazinone ring formation from Asp- or Glu-containing dipeptidyl chloromethyl ketones : during the reaction, rapid decarboxylation from a carboxymethyl group at position 3 of 2(1H)-pyrazinone occurred due to the low electron density at position 3 of 2 (1H)-pyrazinone.

• 公益社団法人日本薬学会の論文
• 1996-11-15

著者

• Taguchi Hiroyuki

  College Of Pharmacy Nihon University

• OKADA Yoshio

  Faculty of Pharmaceutical Sciences, Kobe Gakuin University

• Okada Yoshio

  Faculty Of Pharmaceutical Sciences Kobe Gakuin University

• YOKOI Toshio

  Faculty of Pharmaceutical Sciences, Kobe Gakuin University

• YOKOI Toshio

  The Graduate School of Food and Medicinal Sciences, Kobe Gakuin University

• TAGUCHI Hiroaki

  Faculty of Pharmaceutical Sciences, Kobe Gakuin University

• Yokoi T

  Kobe‐gakuin Univ. Hyogo Jpn

• Yamamoto T

  R&d Laboratories Nippon Organon K.k.

• Taguchi H

  Kobe Pharmaceutical Univ. Kobe Jpn

• Taguchi Hiroaki

  Faculty Of Pharmaceutical Sciences Kobe-gakuin University

• Yokoi Toshio

  Faculty Of Pharmaceutical Sciences And High-technology Research Center Kobe-gakuin University

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