Carnosic Acid, a Component of Rosemary (Rosmarinus officinalis L.), Promotes Synthesis of Nerve Growth Factor in T98G Human Glioblastoma Cells(Medicinal Chemistry)

スポンサーリンク

概要

• 論文の詳細を見る

• Nerve growth factor (NGF) is a factor vital for the growth and functional maintenance of nerve tissue. The authors found that a rosemary (Rosmarinus officinalis L.) extract enhanced the production of NGF in T98G human glioblastoma cells. Furthermore, the results indicated that carnosic acid and carnosol, which are major components of the rosemary extract, were able to promote markedly enhanced synthesis of NGF.

• 公益社団法人日本薬学会の論文
• 2003-11-01

著者

• YOKOI Toshio

  The Graduate School of Food and Medicinal Sciences, Kobe Gakuin University

• Yokoi T

  Faculty Of Pharmaceutical Sciences And High-technology Research Center Kobe-gakuin University

• Yokoi T

  Kobe‐gakuin Univ. Hyogo Jpn

• Kosaka K

  Beauty Care Products Division Health Care Business Group Nagase & Co. Ltd.

• Yamamoto T

  R&d Laboratories Nippon Organon K.k.

• Yokoi Toshio

  Faculty Of Pharmaceutical Sciences And High-technology Research Center Kobe-gakuin University

• Kosaka Kunio

  Beauty Care Products Division Health Care Business Group Nagase & Co. Ltd.

• Yokoi T

  Fucunlty Of Pharmaceutical Sciences Kobe Gakuin University

関連論文

• Amino Acids and Peptides. XL. Synthesis of Ac-Tyr-Val-Ala-Asp-MCA Using Newly Developed Acetylating Reagent
• Antimalarial Agents. III. Mechanism of Action of Artesunate against Plasmodium berghei Infection(Pharmacological)
• Amino Acids and Peptides. LI. Application of the 2-Adamantyloxycarbonyl (2-Adoc) Group to the Protection of the Hydroxyl Function of Tyrosine in Peptide Synthesis
• Development of μ-Receptor Selective Opioid Mimetics Derived from Endomorphin Sequences
• The Antiproliferative Activities of Somatostatin Analogs on Various Tumor Cells
• Roles of Each Component of μ-Opioid Ligands Containing Dmt-Pyrazinones
• Studies on the Mechanism of 1,2-Dihydropyrazin-2-one Ring Formation from Dipeptidyl Chloromethyl Ketone and Its Chemical Properties : Immediate Deamination during Catalytic Hydrogenation
• Synthesis and Bioactivity of Novel Type Pyrazinone Ring-Containing μ-Opioid Ligands
• Generation of a Selective Agonist for Mu-Opioid Receptors by the Dimerization of 2', 6'-Dimethyl-L-Tyrosine through Pyrazinone
• Synthesis of Somatostatin Analogs and Their Antitumor Activities
• The Structure-Activity Relationship of Dmt-NH-X
• Synthesis of New Pyrazinone Ring-Containing Opioid Mimetics and Studies on Their Structure-Activity Relationship
• Stereoselective Synthesis of Unique L-Tyrosine Analogs : Development of Novel μ-Opioid Receptor Ligands
• Synthesis of Opioid Mimetics Containing a Pyrazinone Ring and Their Activities
• Synthesis of Endomorphin-2 Analogues, Studies on Their Activities for Opioid Receptors, and Three Dimensional Structure
• Synthesis of Pyrazinone Ring-Containing Opioid Mimetics and Examination of Their Opioid Receptor-Binding Activity
• Design and Synthesis of Pyrazinone Ring-Containing Opioid Mimetics and Examination of Their Opioid Receptor-Binding Activity
• Amino Acids and Peptides. LII. Design and Synthesis of Opioid Mimetics Containing a Pyrazinone Ring and Examinaiton of Their Opioid Receptor Binding Activity
• Synthesis of Pyrazinone Ring-Containing Tyrosine Derivatives and Examination of Their Binding Activity with Opioid Receptors
• Preparation and Pharmacological Evaluation of Novel Glycoprotein (Gp) IIb/IIIa Antagonists. 2. Condensed Heterocyclic Derivatives
• Preparation and Pharmacological Evaluation of Novel Glycoprotein (Gp) IIb/IIIa Antagonists. 1. The Selection of Naphthalene Derivatives
• Application of Amino Acid Boron Complexes to Introduction of Side Chain Protecting Groups
• Synthesis of 2(1H)-Pyrazinone Derivatives from Dipeptides and Its Application to the Development of Proteinase Inhibitor
• The Structure-Activity Relationship of [Dmt^1]Endomorphin-2 Derivatives
• The Structure-Activity Relationship of the Opioidmimetics Containing 2(1H)-Pyrazinone Ring as a Linker and Observation of Deamination during Synthesis
• Design of Opioidmimetics : Dimerization of 2', 6'-Dimethyl-L-Tyrosine
• Amino Acids and Peptides. L. Development of a Novel N^π-Protecting Group for Histidine, N^π-2-Adamantyloxymethylhistidine, and Its Application to peptide Synthesis
• DEVELOPMENT OF A NEW N^π-PROTECTING GROUP FOR HISTIDINE, N^π-1-ADAMANTYLOXYMETHYLSHISTIDINE
• Synthesis and Properties of N(π)-1- and 2-Adamantyl-oxymethylhistidines, His[N(π)-1- and 2-Adom]
• Amino Acids and Peptides. XLVII. Facile Synthesis of Flavacol, Deoxymuta-aspergillic Acid and Optically Active Deoxyaspergillic Acid from Dipeptidyl Aldehydes
• Amino Acids and Peptides. XLVI. Introduction of Carboxyl Function into Pyrazinone by Using Newly Developed Procedure for pyrazinone Ring Formation : Observation of Immediate Decarboxylation
• Gastric-Mucous Membrane Protection Activity of Coptisine Derivatives
• Isolation of Free Radical Scavenger from Coptidis Rhizoma
• Gastric Mucous Membrane-Protective Principles of Coptidis Rhizoma
• Structures of Taxchinins L and M, Two New Diterpenoids from Taxus chinensis var. Mairei
• Carnosic Acid, a Component of Rosemary (Rosmarinus officinalis L.), Promotes Synthesis of Nerve Growth Factor in T98G Human Glioblastoma Cells(Medicinal Chemistry)
• Analysis of Gastric Mucosus membrane-protective compounds in Coptidis rhizoma
• Isolation of Free Radical Scavenger from Coptidis Rhizoma
• Gastric Mucous Membrane-Protective Principles of Coptidis Rhizoma
• Synthesis and Anticancer Activities of Lipophyllic Somatostatin Derivatives

もっと見る 閉じる

スポンサーリンク